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- W2018092477 abstract "Objectives NJ is being used to treat inflammatory diseases in Korea. In this study, we attempted to evaluate the effects of NJ on atopic dermatitis (AD)-like lesions and mast cell-mediated allergy inflammation in vivo and in vitro. Methods and Results We investigated to ascertain the pharmacological effects of NJ on 2,4-dinitrofluorobenzene (DNFB)-induced allergic reactions under in vivo conditions. Additionally, to find possible explanations for the anti-inflammatory mechanisms of NJ, we evaluated the regulatory effects of NJ on the level of inflammatory mediators in phorbol 12-myristate 13-acetate plus calcium ionophore A23187 (PMACI)-stimulated human mast cells (HMC-1). Conclusions NJ inhibited the production of the inflammatory cytokines (IgE, IL-6, IL-8 and TNF-<TEX>${alpha}$</TEX>) significantly in vivo and in vitro." @default.
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- W2018092477 date "2012-05-31" @default.
- W2018092477 modified "2023-10-11" @default.
- W2018092477 title "Effects of Nardostachys Jatamansi on Atopic Dermatitis-like Skin Lesions" @default.
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- W2018092477 doi "https://doi.org/10.7778/jpkm.2012.26.2.013" @default.
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