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- W2018097885 abstract "Two novel indole C-glycosides, which were the first reported alkaloids C-glycosides from Isatis indigotica, together with five known alkaloids were isolated. The novel alkaloids were elucidated to be indole-3-acetonitrile-4-methoxy-2-C-β-D-glucopyranoside (1) and N-methoxy-indole-3-acetonitrile-2-C-β-D-glucopyranoside (2) on the basis of spectroscopic analysis. 1 exhibited significant cytotoxic activities against human myeloid leukemia HL-60 and human liver cancer HepG2 cells with the IC50 of 1.3 ± 0.1 and 2.1 ± 0.3 μM, respectively. 2 showed potential cytotoxic activities against HL-60 and human myeloid leukemia Mata cells with the IC50 of 5.1 ± 0.4 and 12.1 ± 0.8 μM, respectively." @default.
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- W2018097885 date "2011-03-01" @default.
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- W2018097885 title "Novel indole C-glycosides from Isatis indigotica and their potential cytotoxic activity" @default.
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- W2018097885 doi "https://doi.org/10.1016/j.fitote.2010.10.016" @default.
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