FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018099384> ?p ?o ?g. }

• W2018099384 endingPage "1341" @default.
• W2018099384 startingPage "1330" @default.
• W2018099384 abstract "Objective: To report QT prolongation potential in selective serotonin reuptake inhibitors (SSRIs) in order to advise clinicians on safe use of SSRIs other than citalopram in light of citalopram warnings. Data Sources: Primary literature and case reports were identified through a systematic search. Data from drug manufacturers, package inserts, and the ArizonaCERT database were also utilized. Study Selection and Data Extraction: English-language studies and case reports were included. Data Synthesis: Studies demonstrate possible dose-related clinically significant QT prolongation with escitalopram. Fluoxetine, fluvoxamine, and sertraline at traditional doses demonstrate a lack of clinically significant increases in QTc in the majority of studies. Further, paroxetine monotherapy shows a lack of clinically significant QTc prolongation in all studies. However, case reports or reporting tools still link these SSRIs with QTc prolongation. Fluoxetine, escitalopram, and sertraline used in post–acute coronary syndrome patients did not demonstrate risk of QTc prolongation. Conclusion: For clinicians who choose not to use citalopram due to recent Food and Drug Administration (FDA) recommendations, other antidepressants within this class may be considered. When citalopram is not utilized based on risk factors for TdP, use of escitalopram is not likely the safest alternative. Based on current literature, fluoxetine, fluvoxamine, and sertraline appear to have similar, low risk for QT prolongation, and paroxetine appears to have the lowest risk. However, there are significant limitations in interpreting the studies, including varying definitions of significant QT prolongation. Therefore, choice of an alternative SSRI should be based on individual risk factors for arrhythmias and other patient-specific factors." @default.
• W2018099384 created "2016-06-24" @default.
• W2018099384 creator A5019419681 @default.
• W2018099384 creator A5057409502 @default.
• W2018099384 date "2013-10-01" @default.
• W2018099384 modified "2023-10-10" @default.
• W2018099384 title "A Comparison of the Risk of QT Prolongation Among SSRIs" @default.
• W2018099384 cites W1586142842 @default.
• W2018099384 cites W1735400834 @default.
• W2018099384 cites W1963482722 @default.
• W2018099384 cites W1969544443 @default.
• W2018099384 cites W1970474777 @default.
• W2018099384 cites W1970542948 @default.
• W2018099384 cites W1974801087 @default.
• W2018099384 cites W1975324279 @default.
• W2018099384 cites W1976482322 @default.
• W2018099384 cites W1980873104 @default.
• W2018099384 cites W2002097094 @default.
• W2018099384 cites W2007382799 @default.
• W2018099384 cites W2020304655 @default.
• W2018099384 cites W2027035600 @default.
• W2018099384 cites W2027791666 @default.
• W2018099384 cites W2029965602 @default.
• W2018099384 cites W2036988497 @default.
• W2018099384 cites W2038341506 @default.
• W2018099384 cites W2044548066 @default.
• W2018099384 cites W2045132293 @default.
• W2018099384 cites W2048621290 @default.
• W2018099384 cites W2052109051 @default.
• W2018099384 cites W2058709886 @default.
• W2018099384 cites W2060549334 @default.
• W2018099384 cites W2062844762 @default.
• W2018099384 cites W2076296680 @default.
• W2018099384 cites W2076410398 @default.
• W2018099384 cites W2085454885 @default.
• W2018099384 cites W2086920841 @default.
• W2018099384 cites W2088722048 @default.
• W2018099384 cites W2100004795 @default.
• W2018099384 cites W2103631073 @default.
• W2018099384 cites W2105063639 @default.
• W2018099384 cites W2108190315 @default.
• W2018099384 cites W2108830519 @default.
• W2018099384 cites W2109039468 @default.
• W2018099384 cites W2125434307 @default.
• W2018099384 cites W2133527619 @default.
• W2018099384 cites W2136160652 @default.
• W2018099384 cites W2141625451 @default.
• W2018099384 cites W2149901252 @default.
• W2018099384 cites W2158245987 @default.
• W2018099384 cites W2162857263 @default.
• W2018099384 cites W2163966221 @default.
• W2018099384 cites W2165464052 @default.
• W2018099384 cites W2334399840 @default.
• W2018099384 cites W2917205406 @default.
• W2018099384 cites W4235968416 @default.
• W2018099384 doi "https://doi.org/10.1177/1060028013501994" @default.
• W2018099384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24259697" @default.
• W2018099384 hasPublicationYear "2013" @default.
• W2018099384 type Work @default.
• W2018099384 sameAs 2018099384 @default.
• W2018099384 citedByCount "102" @default.
• W2018099384 countsByYear W20180993842014 @default.
• W2018099384 countsByYear W20180993842015 @default.
• W2018099384 countsByYear W20180993842016 @default.
• W2018099384 countsByYear W20180993842017 @default.
• W2018099384 countsByYear W20180993842018 @default.
• W2018099384 countsByYear W20180993842019 @default.
• W2018099384 countsByYear W20180993842020 @default.
• W2018099384 countsByYear W20180993842021 @default.
• W2018099384 countsByYear W20180993842022 @default.
• W2018099384 countsByYear W20180993842023 @default.
• W2018099384 crossrefType "journal-article" @default.
• W2018099384 hasAuthorship W2018099384A5019419681 @default.
• W2018099384 hasAuthorship W2018099384A5057409502 @default.
• W2018099384 hasConcept C118441451 @default.
• W2018099384 hasConcept C126322002 @default.
• W2018099384 hasConcept C170493617 @default.
• W2018099384 hasConcept C2775864247 @default.
• W2018099384 hasConcept C2776134451 @default.
• W2018099384 hasConcept C2777490545 @default.
• W2018099384 hasConcept C2777669559 @default.
• W2018099384 hasConcept C2777828372 @default.
• W2018099384 hasConcept C2779177272 @default.
• W2018099384 hasConcept C2779583969 @default.
• W2018099384 hasConcept C2779703243 @default.
• W2018099384 hasConcept C2779910183 @default.
• W2018099384 hasConcept C2780486423 @default.
• W2018099384 hasConcept C2781161787 @default.
• W2018099384 hasConcept C42219234 @default.
• W2018099384 hasConcept C71924100 @default.
• W2018099384 hasConcept C98274493 @default.
• W2018099384 hasConceptScore W2018099384C118441451 @default.
• W2018099384 hasConceptScore W2018099384C126322002 @default.
• W2018099384 hasConceptScore W2018099384C170493617 @default.
• W2018099384 hasConceptScore W2018099384C2775864247 @default.
• W2018099384 hasConceptScore W2018099384C2776134451 @default.
• W2018099384 hasConceptScore W2018099384C2777490545 @default.
• W2018099384 hasConceptScore W2018099384C2777669559 @default.

• next