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- W2018114510 abstract "Voltage-activated ionic currents and currents induced by step changes in proton concentration (pH 7.9 6.7) were studied in early embryonic neurons from Hirudo medicinalis. Ganglia were dissociated at embryonic day (E) 8 15, and the largest neurons were investigated using whole-cell patch clamp recording. All cells studied displayed voltage-activated Na+ and Ca2+ currents. Step changes in pH induced sustained currents which reversed at the equilibrium potential for Cl− and were blocked by substituting Cl− with acetate or sulfate. These currents thus differ in their ion selectivity from proton-induced currents in vertebrate neurons which are carried by Na+." @default.
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- W2018114510 date "1989-01-01" @default.
- W2018114510 modified "2023-09-25" @default.
- W2018114510 title "Proton-induced chloride current and voltageactivated Na+ and Ca2+ currents in embryonic neurons from the medicinal leech (Hirudo medicinalis)" @default.
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- W2018114510 doi "https://doi.org/10.1016/0304-3940(89)90053-0" @default.
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