FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018123132> ?p ?o ?g. }

• W2018123132 endingPage "e164" @default.
• W2018123132 startingPage "e162" @default.
• W2018123132 abstract "Dysfibrinogenemia is a rare congenital disorder characterised by mutations in either of the three fibrinogen genes (FGA, FGB, FGG) that encode for the three polypeptide chains (Aα,Bβ,γ) of the fibrinogen molecule. It is inherited as a dominant trait and most patients are heterozygous for missense mutations which allow secretion of the mutant fibrinogen in the circulation. Many dysfibrinogenemias have been characterized at the functional level, causative mutations have been found to have deleterious effects on fibrin polymerization, fibrin crosslinking by FXIIIa as well as fibrinolysis. Most carriers of this disorder are asymptomatic, while a minority may present with either thrombotic or bleeding complications. Development of thrombosis in patients with dysfibrinogenemia is usually associated with defects that cause abnormal fibrinopeptide release, defective polymerization, impaired interaction with platelets, defective fibrinolysis and abnormal calcium binding [ [1] Mosesson M.W. Dysfibrinogenemia and thrombosis. Semin Thromb Hemost. 1999; 25: 311-319 Crossref PubMed Scopus (73) Google Scholar ]. Since most carriers are asymptomatic, it can be postulated that the presence of other inherited predisposing factors might trigger the development of thrombotic or bleeding complications in dysfibrinogenemia patients. More than 400 cases of dysfibrinogenemia have been reported so far, however there are only limited data on the coexistence of prothrombotic mutations in these patients and on the effect of double carriership on the risk for thrombosis. Reports addressing the involvement of additional predisposing genetic defects are interesting and strengthen the hypothesis that coexistence of multiple risk factors may trigger development of thrombosis among the rare dysfibrinogenemia panel." @default.
• W2018123132 created "2016-06-24" @default.
• W2018123132 creator A5009034949 @default.
• W2018123132 creator A5022957457 @default.
• W2018123132 creator A5028425170 @default.
• W2018123132 creator A5032920393 @default.
• W2018123132 creator A5035132045 @default.
• W2018123132 creator A5059033679 @default.
• W2018123132 date "2010-08-01" @default.
• W2018123132 modified "2023-10-14" @default.
• W2018123132 title "Coexisting dysfibrinogenemia (γArg275His) and FV Leiden associated with thrombosis (Fibrinogen Crete)" @default.
• W2018123132 cites W1531281563 @default.
• W2018123132 cites W1605065455 @default.
• W2018123132 cites W198146487 @default.
• W2018123132 cites W1985198125 @default.
• W2018123132 cites W1985461293 @default.
• W2018123132 cites W2038158926 @default.
• W2018123132 cites W2044694435 @default.
• W2018123132 cites W2057802602 @default.
• W2018123132 cites W2097532633 @default.
• W2018123132 cites W2124599289 @default.
• W2018123132 cites W2240017863 @default.
• W2018123132 cites W2395427351 @default.
• W2018123132 cites W4249405018 @default.
• W2018123132 doi "https://doi.org/10.1016/j.thromres.2010.04.011" @default.
• W2018123132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20546853" @default.
• W2018123132 hasPublicationYear "2010" @default.
• W2018123132 type Work @default.
• W2018123132 sameAs 2018123132 @default.
• W2018123132 citedByCount "13" @default.
• W2018123132 countsByYear W20181231322012 @default.
• W2018123132 countsByYear W20181231322013 @default.
• W2018123132 countsByYear W20181231322014 @default.
• W2018123132 countsByYear W20181231322015 @default.
• W2018123132 countsByYear W20181231322016 @default.
• W2018123132 countsByYear W20181231322017 @default.
• W2018123132 countsByYear W20181231322018 @default.
• W2018123132 countsByYear W20181231322020 @default.
• W2018123132 countsByYear W20181231322021 @default.
• W2018123132 countsByYear W20181231322023 @default.
• W2018123132 crossrefType "journal-article" @default.
• W2018123132 hasAuthorship W2018123132A5009034949 @default.
• W2018123132 hasAuthorship W2018123132A5022957457 @default.
• W2018123132 hasAuthorship W2018123132A5028425170 @default.
• W2018123132 hasAuthorship W2018123132A5032920393 @default.
• W2018123132 hasAuthorship W2018123132A5035132045 @default.
• W2018123132 hasAuthorship W2018123132A5059033679 @default.
• W2018123132 hasConcept C104317684 @default.
• W2018123132 hasConcept C126322002 @default.
• W2018123132 hasConcept C137916694 @default.
• W2018123132 hasConcept C203014093 @default.
• W2018123132 hasConcept C2776825266 @default.
• W2018123132 hasConcept C2777910003 @default.
• W2018123132 hasConcept C2779036427 @default.
• W2018123132 hasConcept C2779936836 @default.
• W2018123132 hasConcept C2780868729 @default.
• W2018123132 hasConcept C501734568 @default.
• W2018123132 hasConcept C54173615 @default.
• W2018123132 hasConcept C54355233 @default.
• W2018123132 hasConcept C71924100 @default.
• W2018123132 hasConcept C75563809 @default.
• W2018123132 hasConcept C86803240 @default.
• W2018123132 hasConcept C89560881 @default.
• W2018123132 hasConcept C90924648 @default.
• W2018123132 hasConceptScore W2018123132C104317684 @default.
• W2018123132 hasConceptScore W2018123132C126322002 @default.
• W2018123132 hasConceptScore W2018123132C137916694 @default.
• W2018123132 hasConceptScore W2018123132C203014093 @default.
• W2018123132 hasConceptScore W2018123132C2776825266 @default.
• W2018123132 hasConceptScore W2018123132C2777910003 @default.
• W2018123132 hasConceptScore W2018123132C2779036427 @default.
• W2018123132 hasConceptScore W2018123132C2779936836 @default.
• W2018123132 hasConceptScore W2018123132C2780868729 @default.
• W2018123132 hasConceptScore W2018123132C501734568 @default.
• W2018123132 hasConceptScore W2018123132C54173615 @default.
• W2018123132 hasConceptScore W2018123132C54355233 @default.
• W2018123132 hasConceptScore W2018123132C71924100 @default.
• W2018123132 hasConceptScore W2018123132C75563809 @default.
• W2018123132 hasConceptScore W2018123132C86803240 @default.
• W2018123132 hasConceptScore W2018123132C89560881 @default.
• W2018123132 hasConceptScore W2018123132C90924648 @default.
• W2018123132 hasIssue "2" @default.
• W2018123132 hasLocation W20181231321 @default.
• W2018123132 hasLocation W20181231322 @default.
• W2018123132 hasOpenAccess W2018123132 @default.
• W2018123132 hasPrimaryLocation W20181231321 @default.
• W2018123132 hasRelatedWork W1991243300 @default.
• W2018123132 hasRelatedWork W1992410460 @default.
• W2018123132 hasRelatedWork W2059336501 @default.
• W2018123132 hasRelatedWork W2273180610 @default.
• W2018123132 hasRelatedWork W2402767799 @default.
• W2018123132 hasRelatedWork W2732267486 @default.
• W2018123132 hasRelatedWork W2808986224 @default.
• W2018123132 hasRelatedWork W3045946681 @default.
• W2018123132 hasRelatedWork W3194956049 @default.
• W2018123132 hasRelatedWork W4210979105 @default.
• W2018123132 hasVolume "126" @default.
• W2018123132 isParatext "false" @default.

• next