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• W2018133764 abstract "We describe here a 10-year-old patient with high levels of serum IgE and inflammatory myopathy whose muscle fibers exhibit excessive autophagy. Previous studies have demonstrated surface expression of class I MHC antigens on muscle fibers from patients with inflammatory myopathy. The muscle fibers of this patients showed marked expression of both class I and class II MHC antigens. The reaction products were demonstrated not only on sarcolemma but also in and around some vacuoles. Both CD4-positive and CD8-positive T-lymphocytes were noted in inflammatory exudates surrounding these fibers but B-lymphocytes were rare. We hypothesize that myocyte expression of both class I and class II antigens may play a role in the pathogenesis of this new type of inflammatory myopathy." @default.
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• W2018133764 date "1991-11-01" @default.
• W2018133764 modified "2023-09-25" @default.
• W2018133764 title "Vacuolar myositis with expression of both MHC class I and class II antigens on skeletal muscle fibers" @default.
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• W2018133764 doi "https://doi.org/10.1016/0022-510x(91)90195-d" @default.
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