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- W2018135583 abstract "Hooded rats were trained in a straight alley to repeatedly press a lever placed at one end of the alley until a discriminative auditory signal (SD) appeared and then to run for a water reward (Rd) available at the other end. During training SD was spatially contiguous with Rd; then SD was placed above the bar (spatially discontiguous with Rd). In normal animals SD-Rd discontiguity caused abrupt and significant increases in lever press duration, latency to leave the lever area, and lever press perseveration (conflict). Conflict was not seen in postoperatively trained fimbria-fornix-damaged rats. However, if lesions were made after training but prior to testing under the SD-Rd discontiguity condition, conflict occurred also in the lesioned subjects. Our results indicate that normal rats learn and maintain responding to informative cues throughout conditioning, and this persisting cue-directed response (sign tracking) is absent in fimbria-fornix-lesioned rats. It is suggested that the impaired performance of fimbria-fornix-lesioned rats lies in their ability to create a new goal independent of the primary reinforcer." @default.
- W2018135583 created "2016-06-24" @default.
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- W2018135583 date "1980-06-01" @default.
- W2018135583 modified "2023-10-15" @default.
- W2018135583 title "Importance of cue location for intact and fimbria-fornix-lesioned rats" @default.
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- W2018135583 doi "https://doi.org/10.1016/s0163-1047(80)90508-7" @default.
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