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- W201818291 abstract "Most older people prefer to remain at home rather than enter residential care. Consequently, community care has focussed on allowing older people to remain at home and receive the required health and social care. Currently in New Zealand, the District Health Boards have three different innovative models of care that aim to allow an older person to ‘age-in-place’.Three randomised controlled trials were conducted to evaluate the cost-effectiveness of these new services compared to usual care in reducing mortality, delaying/preventing residential care placement and various social and functional measures. The caregiver burden was also measured. A prospective meta-analysis was designed and implemented containing these three stand-alone trials with different ageing-in-place models of care from three districts within New Zealand. One stand-alone trial was randomised at the GP level, whereas the other two trials were randomised at individual level due to the structure of the different service models. Participants who have the same GP are more likely to have similar characteristics than those from different GPs. Hence, the intra-cluster correlation coefficient (ICC) at GP level needs to be taken into account when conducting statistical analysis. Standard statistical analysis is not applicable for trials randomised at GP level.Therefore, metaanalysis was used to estimate overall treatment effect by pooling the results of the two individual randomised trials together with the results from the cluster-randomised trial. This presentation aims to give the perspective of a statistician during different stages of the study. Challenges that arose during the design and monitoring stages of the study as well as the statistical analysis approach for this complex study design will be discussed." @default.
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- W201818291 title "Statistical Challenges during the Assessments of Services Promoting Independence and Recovery in Elders (ASPIRE) Trial" @default.
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