FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018183977> ?p ?o ?g. }

• W2018183977 endingPage "185" @default.
• W2018183977 startingPage "179" @default.
• W2018183977 abstract "We studied plasma adiponectin, insulin sensitivity, and insulin secretion before and after oral glucose challenge in normal glucose tolerant, impaired glucose tolerant, and type 2 diabetic first degree relatives of African-American patients with type 2 diabetes.We studied 19 subjects with normal glucose tolerance (NGT), 8 with impaired glucose tolerance (IGT), and 14 with type 2 diabetes. Serum glucose, insulin, C-peptide, and plasma adiponectin levels were measured before and 2 hours after oral glucose tolerance test. Homeostasis model assessment-insulin resistance index (HOMA-IR) and HOMA-beta cell function were calculated in each subject using HOMA. We empirically defined insulin sensitivity as HOMA-IR<2.68 and insulin resistance as HOMA-IR>2.68.Subjects with IGT and type 2 diabetes were more insulin resistant (as assessed by HOMA-IR) when compared with NGT subjects. Mean plasma fasting adiponectin levels were significantly lower in the type 2 diabetes group when compared with NGT and IGT groups. Plasma adiponectin levels were 2-fold greater (11.09+/-4.98 vs. 6.42+/-3.3811 microg/mL) in insulin-sensitive (HOMA-IR, 1.74+/-0.65) than in insulin-resistant (HOMA-IR, 5.12+/-2.14) NGT subjects. Mean plasma adiponectin levels were significantly lower in the glucose tolerant, insulin-resistant subjects than in the insulin sensitive NGT subjects and were comparable with those of the patients with newly diagnosed type 2 diabetes. We found significant inverse relationships of adiponectin with HOMA-IR (r=-0.502, p=0.046) and with HOMA-beta cell function (r=-0.498, p=0.042) but not with the percentage body fat (r=-0.368, p=0.063), serum glucose, BMI, age, and glycosylated hemoglobin A1C (%A1C).In summary, we found that plasma adiponectin levels were significantly lower in insulin-resistant, non-diabetic first degree relatives of African-American patients with type 2 diabetes and in those with newly diagnosed type 2 diabetes. We conclude that a decreased plasma adiponectin and insulin resistance coexist in a genetically prone subset of first degree African-American relatives before development of IGT and type 2 diabetes." @default.
• W2018183977 created "2016-06-24" @default.
• W2018183977 creator A5023259092 @default.
• W2018183977 creator A5038608054 @default.
• W2018183977 creator A5043493254 @default.
• W2018183977 date "2005-01-01" @default.
• W2018183977 modified "2023-10-03" @default.
• W2018183977 title "Plasma Adiponectin Levels in High Risk African-Americans with Normal Glucose Tolerance, Impaired Glucose Tolerance, and Type 2 Diabetes^**" @default.
• W2018183977 cites W1524321743 @default.
• W2018183977 cites W1570155932 @default.
• W2018183977 cites W1964588842 @default.
• W2018183977 cites W1971963895 @default.
• W2018183977 cites W1976329330 @default.
• W2018183977 cites W2050145350 @default.
• W2018183977 cites W2055945824 @default.
• W2018183977 cites W2059456683 @default.
• W2018183977 cites W2063439586 @default.
• W2018183977 cites W2066175951 @default.
• W2018183977 cites W2076706839 @default.
• W2018183977 cites W2085057119 @default.
• W2018183977 cites W2087306774 @default.
• W2018183977 cites W2095763488 @default.
• W2018183977 cites W2097794068 @default.
• W2018183977 cites W2105391872 @default.
• W2018183977 cites W2111230909 @default.
• W2018183977 cites W2124588973 @default.
• W2018183977 cites W2129316761 @default.
• W2018183977 cites W2131363228 @default.
• W2018183977 cites W2132681327 @default.
• W2018183977 cites W2135298791 @default.
• W2018183977 cites W2144938291 @default.
• W2018183977 cites W2146468718 @default.
• W2018183977 cites W2155904812 @default.
• W2018183977 cites W2157150994 @default.
• W2018183977 cites W2160234571 @default.
• W2018183977 cites W2167761380 @default.
• W2018183977 cites W2321082256 @default.
• W2018183977 cites W4233562854 @default.
• W2018183977 doi "https://doi.org/10.1038/oby.2005.23" @default.
• W2018183977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15761178" @default.
• W2018183977 hasPublicationYear "2005" @default.
• W2018183977 type Work @default.
• W2018183977 sameAs 2018183977 @default.
• W2018183977 citedByCount "46" @default.
• W2018183977 countsByYear W20181839772012 @default.
• W2018183977 countsByYear W20181839772013 @default.
• W2018183977 countsByYear W20181839772014 @default.
• W2018183977 countsByYear W20181839772015 @default.
• W2018183977 countsByYear W20181839772016 @default.
• W2018183977 countsByYear W20181839772017 @default.
• W2018183977 countsByYear W20181839772018 @default.
• W2018183977 countsByYear W20181839772019 @default.
• W2018183977 countsByYear W20181839772021 @default.
• W2018183977 crossrefType "journal-article" @default.
• W2018183977 hasAuthorship W2018183977A5023259092 @default.
• W2018183977 hasAuthorship W2018183977A5038608054 @default.
• W2018183977 hasAuthorship W2018183977A5043493254 @default.
• W2018183977 hasBestOaLocation W20181839771 @default.
• W2018183977 hasConcept C126322002 @default.
• W2018183977 hasConcept C134018914 @default.
• W2018183977 hasConcept C2776782570 @default.
• W2018183977 hasConcept C2777180221 @default.
• W2018183977 hasConcept C2777391703 @default.
• W2018183977 hasConcept C2779306644 @default.
• W2018183977 hasConcept C2780609358 @default.
• W2018183977 hasConcept C2780833929 @default.
• W2018183977 hasConcept C555293320 @default.
• W2018183977 hasConcept C63645605 @default.
• W2018183977 hasConcept C71924100 @default.
• W2018183977 hasConceptScore W2018183977C126322002 @default.
• W2018183977 hasConceptScore W2018183977C134018914 @default.
• W2018183977 hasConceptScore W2018183977C2776782570 @default.
• W2018183977 hasConceptScore W2018183977C2777180221 @default.
• W2018183977 hasConceptScore W2018183977C2777391703 @default.
• W2018183977 hasConceptScore W2018183977C2779306644 @default.
• W2018183977 hasConceptScore W2018183977C2780609358 @default.
• W2018183977 hasConceptScore W2018183977C2780833929 @default.
• W2018183977 hasConceptScore W2018183977C555293320 @default.
• W2018183977 hasConceptScore W2018183977C63645605 @default.
• W2018183977 hasConceptScore W2018183977C71924100 @default.
• W2018183977 hasIssue "1" @default.
• W2018183977 hasLocation W20181839771 @default.
• W2018183977 hasLocation W20181839772 @default.
• W2018183977 hasOpenAccess W2018183977 @default.
• W2018183977 hasPrimaryLocation W20181839771 @default.
• W2018183977 hasRelatedWork W1982589044 @default.
• W2018183977 hasRelatedWork W1988439151 @default.
• W2018183977 hasRelatedWork W1992838000 @default.
• W2018183977 hasRelatedWork W2026316039 @default.
• W2018183977 hasRelatedWork W2028627743 @default.
• W2018183977 hasRelatedWork W2074673535 @default.
• W2018183977 hasRelatedWork W2120688902 @default.
• W2018183977 hasRelatedWork W2136767406 @default.
• W2018183977 hasRelatedWork W2375944679 @default.
• W2018183977 hasRelatedWork W3028839963 @default.
• W2018183977 hasVolume "13" @default.
• W2018183977 isParatext "false" @default.
• W2018183977 isRetracted "false" @default.

• next