Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018184777> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2018184777 endingPage "173" @default.
- W2018184777 startingPage "167" @default.
- W2018184777 abstract "Antibodies with their ability to selectivity bind antigens have been of great interest in targeting radiation, drugs and toxins to tumors. Limited success in delivery of radioactivity has been enjoyed with conventional attachment to antibodies. This is due to slow tumor targeting processes and slow disappearance from blood and variable uptake and disappearance from the excretory organs, liver and kidney. Preliminary studies in animal models and patients have shown promise in increasing the tumor to blood exposure ratio by pretargeting antibody followed by small molecule delivery of radioactivity using a molecular capture system. Efficient capture of the small molecule radioactivity carrier by tumor localized antibody and rapid clearance and excretion of the untargeted radioactivity decreases the background problem for imaging and lowers marrow toxicity for radioimmunotherapy. Small peptide ligands that bind to receptor bearing tumors offer similar advantages." @default.
- W2018184777 created "2016-06-24" @default.
- W2018184777 creator A5003924924 @default.
- W2018184777 creator A5026941412 @default.
- W2018184777 creator A5079601865 @default.
- W2018184777 creator A5090778506 @default.
- W2018184777 date "1994-01-01" @default.
- W2018184777 modified "2023-09-27" @default.
- W2018184777 title "Approaches to improved antibody- and peptide-mediated targeting for imaging and therapy of cancer" @default.
- W2018184777 cites W1964013529 @default.
- W2018184777 cites W2000658226 @default.
- W2018184777 cites W2033304141 @default.
- W2018184777 cites W2033460249 @default.
- W2018184777 cites W2048097813 @default.
- W2018184777 cites W2053694429 @default.
- W2018184777 cites W2069451410 @default.
- W2018184777 cites W2099564842 @default.
- W2018184777 cites W2155662786 @default.
- W2018184777 cites W2176780488 @default.
- W2018184777 cites W2295467440 @default.
- W2018184777 cites W4229732777 @default.
- W2018184777 cites W4236530705 @default.
- W2018184777 doi "https://doi.org/10.1016/0168-3659(94)90163-5" @default.
- W2018184777 hasPublicationYear "1994" @default.
- W2018184777 type Work @default.
- W2018184777 sameAs 2018184777 @default.
- W2018184777 citedByCount "25" @default.
- W2018184777 countsByYear W20181847772016 @default.
- W2018184777 countsByYear W20181847772020 @default.
- W2018184777 countsByYear W20181847772022 @default.
- W2018184777 crossrefType "journal-article" @default.
- W2018184777 hasAuthorship W2018184777A5003924924 @default.
- W2018184777 hasAuthorship W2018184777A5026941412 @default.
- W2018184777 hasAuthorship W2018184777A5079601865 @default.
- W2018184777 hasAuthorship W2018184777A5090778506 @default.
- W2018184777 hasConcept C121608353 @default.
- W2018184777 hasConcept C126322002 @default.
- W2018184777 hasConcept C147483822 @default.
- W2018184777 hasConcept C159654299 @default.
- W2018184777 hasConcept C161624437 @default.
- W2018184777 hasConcept C185592680 @default.
- W2018184777 hasConcept C203014093 @default.
- W2018184777 hasConcept C2776146153 @default.
- W2018184777 hasConcept C2777836882 @default.
- W2018184777 hasConcept C2779281246 @default.
- W2018184777 hasConcept C502942594 @default.
- W2018184777 hasConcept C542903549 @default.
- W2018184777 hasConcept C55493867 @default.
- W2018184777 hasConcept C71924100 @default.
- W2018184777 hasConcept C98274493 @default.
- W2018184777 hasConceptScore W2018184777C121608353 @default.
- W2018184777 hasConceptScore W2018184777C126322002 @default.
- W2018184777 hasConceptScore W2018184777C147483822 @default.
- W2018184777 hasConceptScore W2018184777C159654299 @default.
- W2018184777 hasConceptScore W2018184777C161624437 @default.
- W2018184777 hasConceptScore W2018184777C185592680 @default.
- W2018184777 hasConceptScore W2018184777C203014093 @default.
- W2018184777 hasConceptScore W2018184777C2776146153 @default.
- W2018184777 hasConceptScore W2018184777C2777836882 @default.
- W2018184777 hasConceptScore W2018184777C2779281246 @default.
- W2018184777 hasConceptScore W2018184777C502942594 @default.
- W2018184777 hasConceptScore W2018184777C542903549 @default.
- W2018184777 hasConceptScore W2018184777C55493867 @default.
- W2018184777 hasConceptScore W2018184777C71924100 @default.
- W2018184777 hasConceptScore W2018184777C98274493 @default.
- W2018184777 hasIssue "1-3" @default.
- W2018184777 hasLocation W20181847771 @default.
- W2018184777 hasOpenAccess W2018184777 @default.
- W2018184777 hasPrimaryLocation W20181847771 @default.
- W2018184777 hasRelatedWork W1979401181 @default.
- W2018184777 hasRelatedWork W1992760392 @default.
- W2018184777 hasRelatedWork W2066823601 @default.
- W2018184777 hasRelatedWork W2184100701 @default.
- W2018184777 hasRelatedWork W2188170947 @default.
- W2018184777 hasRelatedWork W2930828635 @default.
- W2018184777 hasRelatedWork W3169974167 @default.
- W2018184777 hasRelatedWork W4211120843 @default.
- W2018184777 hasRelatedWork W4251714812 @default.
- W2018184777 hasRelatedWork W48525853 @default.
- W2018184777 hasVolume "28" @default.
- W2018184777 isParatext "false" @default.
- W2018184777 isRetracted "false" @default.
- W2018184777 magId "2018184777" @default.
- W2018184777 workType "article" @default.