FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018190136> ?p ?o ?g. }

• W2018190136 abstract "Estrogen and progestin receptor levels (ER and PgR) in tumors from 506 patients with primary breast cancer diagnosed in 1979, 1980, and 1981 were measured by a Scatchard plot analysis. At a median follow-up time of 3.5 years the prognostic value of the receptor levels was evaluated and compared with other tumor and patient characteristics. No relation was found between receptor levels and tumor, lymph node, metastasis (TNM) classification or location of the primary tumor. A significant positive rank correlation was observed between ER and PgR levels (rs = 0.57) and between ER level and age of the patients (rs = 0.39, P less than 0.001). The observed association between ER level and menopause status could not be maintained after correction for age. Independent prognostic factors for overall survival were tumor size (P = 0.002), the number of positive lymph nodes (P less than 0.001), age at primary surgery (P less than 0.001), the PgR level of the tumor (P less than 0.001), but not ER level. Independent prognostic factors for relapse were tumor size (P = 0.003), number of positive lymph nodes (P less than 0.001), age (P = 0.006), menopause status (P = 0.02), PgR level (P = 0.007), but not ER level. Finally, for death rate after relapse the following prognosticators were identified: size of the primary tumor (P = 0.03), number of positive lymph nodes (P = 0.03), age (P = 0.003), site of relapse (P less than 0.001), ER level (P = 0.02), and PgR level (P = 0.04). Patients with tumors containing low positive PgR levels (10 to 20 fmol/mg protein) had a slightly better prognosis than patients with PgR-negative tumors. It is concluded that the PgR level of the primary tumor is a better prognosticator than the ER level. The ER offered no additional ability for discriminating between low- and high-risk patients once PgR was included in the model. In contrast, PgR was capable of improving on the discriminating ability of ER. In addition, patients with tumors containing both PgR and ER showed the best prognosis. Therefore, it is recommended that ER and PgR should be assayed in all breast cancer biopsies." @default.
• W2018190136 created "2016-06-24" @default.
• W2018190136 creator A5019431922 @default.
• W2018190136 creator A5043284259 @default.
• W2018190136 creator A5047299605 @default.
• W2018190136 creator A5080388818 @default.
• W2018190136 creator A5088600258 @default.
• W2018190136 date "1988-02-15" @default.
• W2018190136 modified "2023-09-23" @default.
• W2018190136 title "The prognostic value and relationships of patient characteristics, estrogen and progestin receptors, and site of relapse in primary breast cancer" @default.
• W2018190136 cites W1776236783 @default.
• W2018190136 cites W1927418190 @default.
• W2018190136 cites W1964048542 @default.
• W2018190136 cites W1978093589 @default.
• W2018190136 cites W1981071486 @default.
• W2018190136 cites W1981970812 @default.
• W2018190136 cites W1983298642 @default.
• W2018190136 cites W1987463167 @default.
• W2018190136 cites W1987990339 @default.
• W2018190136 cites W1989798994 @default.
• W2018190136 cites W1993049967 @default.
• W2018190136 cites W1995268204 @default.
• W2018190136 cites W1995815496 @default.
• W2018190136 cites W1999832840 @default.
• W2018190136 cites W2002816686 @default.
• W2018190136 cites W2005879238 @default.
• W2018190136 cites W2013575574 @default.
• W2018190136 cites W2037646360 @default.
• W2018190136 cites W2040368172 @default.
• W2018190136 cites W2043624984 @default.
• W2018190136 cites W2050209592 @default.
• W2018190136 cites W2057524003 @default.
• W2018190136 cites W2057753121 @default.
• W2018190136 cites W2073725809 @default.
• W2018190136 cites W2079808933 @default.
• W2018190136 cites W2080928882 @default.
• W2018190136 cites W2081071475 @default.
• W2018190136 cites W2081089568 @default.
• W2018190136 cites W2083824078 @default.
• W2018190136 cites W2085895382 @default.
• W2018190136 cites W2088332845 @default.
• W2018190136 cites W2089663944 @default.
• W2018190136 cites W2091845968 @default.
• W2018190136 cites W2097280730 @default.
• W2018190136 cites W2153837633 @default.
• W2018190136 cites W2156160049 @default.
• W2018190136 cites W2220500259 @default.
• W2018190136 cites W4255402825 @default.
• W2018190136 doi "https://doi.org/10.1002/1097-0142(19880215)61:4<758::aid-cncr2820610421>3.0.co;2-t" @default.
• W2018190136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3338038" @default.
• W2018190136 hasPublicationYear "1988" @default.
• W2018190136 type Work @default.
• W2018190136 sameAs 2018190136 @default.
• W2018190136 citedByCount "98" @default.
• W2018190136 countsByYear W20181901362012 @default.
• W2018190136 countsByYear W20181901362013 @default.
• W2018190136 countsByYear W20181901362016 @default.
• W2018190136 countsByYear W20181901362017 @default.
• W2018190136 countsByYear W20181901362020 @default.
• W2018190136 crossrefType "journal-article" @default.
• W2018190136 hasAuthorship W2018190136A5019431922 @default.
• W2018190136 hasAuthorship W2018190136A5043284259 @default.
• W2018190136 hasAuthorship W2018190136A5047299605 @default.
• W2018190136 hasAuthorship W2018190136A5080388818 @default.
• W2018190136 hasAuthorship W2018190136A5088600258 @default.
• W2018190136 hasBestOaLocation W20181901361 @default.
• W2018190136 hasConcept C121608353 @default.
• W2018190136 hasConcept C126322002 @default.
• W2018190136 hasConcept C142724271 @default.
• W2018190136 hasConcept C143998085 @default.
• W2018190136 hasConcept C2776607906 @default.
• W2018190136 hasConcept C2777164284 @default.
• W2018190136 hasConcept C2778562196 @default.
• W2018190136 hasConcept C2779013556 @default.
• W2018190136 hasConcept C2779720271 @default.
• W2018190136 hasConcept C2780283643 @default.
• W2018190136 hasConcept C2780849966 @default.
• W2018190136 hasConcept C29456083 @default.
• W2018190136 hasConcept C530470458 @default.
• W2018190136 hasConcept C71924100 @default.
• W2018190136 hasConcept C84606932 @default.
• W2018190136 hasConcept C90924648 @default.
• W2018190136 hasConcept C98717036 @default.
• W2018190136 hasConceptScore W2018190136C121608353 @default.
• W2018190136 hasConceptScore W2018190136C126322002 @default.
• W2018190136 hasConceptScore W2018190136C142724271 @default.
• W2018190136 hasConceptScore W2018190136C143998085 @default.
• W2018190136 hasConceptScore W2018190136C2776607906 @default.
• W2018190136 hasConceptScore W2018190136C2777164284 @default.
• W2018190136 hasConceptScore W2018190136C2778562196 @default.
• W2018190136 hasConceptScore W2018190136C2779013556 @default.
• W2018190136 hasConceptScore W2018190136C2779720271 @default.
• W2018190136 hasConceptScore W2018190136C2780283643 @default.
• W2018190136 hasConceptScore W2018190136C2780849966 @default.
• W2018190136 hasConceptScore W2018190136C29456083 @default.
• W2018190136 hasConceptScore W2018190136C530470458 @default.
• W2018190136 hasConceptScore W2018190136C71924100 @default.
• W2018190136 hasConceptScore W2018190136C84606932 @default.
• W2018190136 hasConceptScore W2018190136C90924648 @default.
• W2018190136 hasConceptScore W2018190136C98717036 @default.

• next