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- W2018205667 abstract "Nitric oxide (NO) reversibly inhibits mitochondrial respiration by competing with oxygen at cytochrome oxidase. Concentrations of NO measured in a range of biological systems are similar to those shown to inhibit cytochrome oxidase and mitochondrial respiration. Inhibition of NO synthesis results in a stimulation of respiration in a number of systems. It is proposed that NO exerts some of its main physiological and pathological effects on cell functions by inhibiting cytochrome oxidase. Further NO may be a physiological regulator of the affinity of mitochondrial respiration for oxygen, enabling mitochondria to act as sensors of oxygen over the physiological range." @default.
- W2018205667 created "2016-06-24" @default.
- W2018205667 creator A5042066616 @default.
- W2018205667 date "1995-08-07" @default.
- W2018205667 modified "2023-10-13" @default.
- W2018205667 title "Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase" @default.
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- W2018205667 doi "https://doi.org/10.1016/0014-5793(95)00763-y" @default.
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