FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018213090> ?p ?o ?g. }

• W2018213090 endingPage "1189" @default.
• W2018213090 startingPage "1179" @default.
• W2018213090 abstract "In the presence of picrotoxin, spontaneous synchronized bursts followed by afterdischarges were recorded from all pyramidal cell regions of the guinea pig hippocampal slice. Excitatory synaptic potentials, which reversed at approx -5 mV, were found to be associated with both the initial burst and each afterdischarge. Afterdischarges were reversibly blocked, leaving the initial synchronized burst intact, by the application of several excitatory amino acid antagonists or by increasing Mg2+ so that the efficacy of synaptic transmission was reduced. All synchronized activity was suppressed by applying an increased concentration of antagonist or by raising Mg2+ and lowering Ca2+ so that synaptic transmission was completely blocked. This synchronized neuronal activity occurred spontaneously in the CA2-3 region when isolated from the CA1 pyramidal cell area and the dentate gyrus. When CA2 was separated from CA3 a synchronized rhythm of single bursts was observed in CA2, while a different, slower, synchronized population discharge consisting of initial bursts followed by afterdischarges occurred in CA3. The smallest completely isolated segments of the CA3 field which spontaneously generated synchronized afterdischarges, comparable to those observed in the intact slice, measured 500-700 microns along the stratum pyramidable. It is concluded that these afterdischarges depend on local neuronal interactions mediated by chemical synaptic mechanisms which may occur within a single population of as few as 1000 CA3 pyramidal cells. The results are consistent with a repeated activation of the same group of synapses, which may release an excitatory amino acid neurotransmitter, being responsible for the initiation of each afterdischarge." @default.
• W2018213090 created "2016-06-24" @default.
• W2018213090 creator A5041541733 @default.
• W2018213090 creator A5057780747 @default.
• W2018213090 creator A5082429924 @default.
• W2018213090 date "1984-08-01" @default.
• W2018213090 modified "2023-10-17" @default.
• W2018213090 title "Synchronized afterdischarges in the hippocampus: Contribution of local synaptic interactions" @default.
• W2018213090 cites W131216487 @default.
• W2018213090 cites W1679118305 @default.
• W2018213090 cites W1953088445 @default.
• W2018213090 cites W1964926188 @default.
• W2018213090 cites W1966474984 @default.
• W2018213090 cites W1966603478 @default.
• W2018213090 cites W1968813087 @default.
• W2018213090 cites W1971778378 @default.
• W2018213090 cites W1973050784 @default.
• W2018213090 cites W1984354543 @default.
• W2018213090 cites W1996961489 @default.
• W2018213090 cites W1997199005 @default.
• W2018213090 cites W1997467371 @default.
• W2018213090 cites W1997648252 @default.
• W2018213090 cites W2005273920 @default.
• W2018213090 cites W2025502564 @default.
• W2018213090 cites W2029126307 @default.
• W2018213090 cites W2033399950 @default.
• W2018213090 cites W2036686141 @default.
• W2018213090 cites W2050215995 @default.
• W2018213090 cites W2052241540 @default.
• W2018213090 cites W2052899121 @default.
• W2018213090 cites W2055536854 @default.
• W2018213090 cites W2055838984 @default.
• W2018213090 cites W2059974504 @default.
• W2018213090 cites W2071766364 @default.
• W2018213090 cites W2078156409 @default.
• W2018213090 cites W2085391134 @default.
• W2018213090 cites W2088807060 @default.
• W2018213090 cites W2089303896 @default.
• W2018213090 cites W2093493277 @default.
• W2018213090 cites W2093980209 @default.
• W2018213090 cites W2095354414 @default.
• W2018213090 cites W2126200952 @default.
• W2018213090 cites W2180941170 @default.
• W2018213090 cites W2255471415 @default.
• W2018213090 cites W2297695555 @default.
• W2018213090 cites W2344349459 @default.
• W2018213090 cites W2409115623 @default.
• W2018213090 cites W2413930114 @default.
• W2018213090 cites W4231727956 @default.
• W2018213090 doi "https://doi.org/10.1016/0306-4522(84)90012-5" @default.
• W2018213090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6090986" @default.
• W2018213090 hasPublicationYear "1984" @default.
• W2018213090 type Work @default.
• W2018213090 sameAs 2018213090 @default.
• W2018213090 citedByCount "195" @default.
• W2018213090 countsByYear W20182130902012 @default.
• W2018213090 countsByYear W20182130902013 @default.
• W2018213090 countsByYear W20182130902014 @default.
• W2018213090 countsByYear W20182130902015 @default.
• W2018213090 countsByYear W20182130902016 @default.
• W2018213090 countsByYear W20182130902017 @default.
• W2018213090 countsByYear W20182130902018 @default.
• W2018213090 countsByYear W20182130902019 @default.
• W2018213090 countsByYear W20182130902020 @default.
• W2018213090 countsByYear W20182130902021 @default.
• W2018213090 countsByYear W20182130902023 @default.
• W2018213090 crossrefType "journal-article" @default.
• W2018213090 hasAuthorship W2018213090A5041541733 @default.
• W2018213090 hasAuthorship W2018213090A5057780747 @default.
• W2018213090 hasAuthorship W2018213090A5082429924 @default.
• W2018213090 hasConcept C112592302 @default.
• W2018213090 hasConcept C12554922 @default.
• W2018213090 hasConcept C148762608 @default.
• W2018213090 hasConcept C169760540 @default.
• W2018213090 hasConcept C170493617 @default.
• W2018213090 hasConcept C17077164 @default.
• W2018213090 hasConcept C185592680 @default.
• W2018213090 hasConcept C195221683 @default.
• W2018213090 hasConcept C200170125 @default.
• W2018213090 hasConcept C2776464000 @default.
• W2018213090 hasConcept C2776885963 @default.
• W2018213090 hasConcept C2778437258 @default.
• W2018213090 hasConcept C2779277159 @default.
• W2018213090 hasConcept C2779324764 @default.
• W2018213090 hasConcept C2780763569 @default.
• W2018213090 hasConcept C2781161787 @default.
• W2018213090 hasConcept C2908647359 @default.
• W2018213090 hasConcept C55493867 @default.
• W2018213090 hasConcept C71924100 @default.
• W2018213090 hasConcept C79636183 @default.
• W2018213090 hasConcept C86803240 @default.
• W2018213090 hasConcept C99454951 @default.
• W2018213090 hasConceptScore W2018213090C112592302 @default.
• W2018213090 hasConceptScore W2018213090C12554922 @default.
• W2018213090 hasConceptScore W2018213090C148762608 @default.
• W2018213090 hasConceptScore W2018213090C169760540 @default.
• W2018213090 hasConceptScore W2018213090C170493617 @default.
• W2018213090 hasConceptScore W2018213090C17077164 @default.

• next