FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018231544> ?p ?o ?g. }

• W2018231544 endingPage "1070" @default.
• W2018231544 startingPage "1062" @default.
• W2018231544 abstract "The incomplete absorption of dietary cholesterol may represent an adaptive intestinal barrier that prevents hypercholesterolemia. To explore this mechanism, we compared cholesterol absorption in 15 normocholesterolemic and 6 hypercholesterolemic (type II) subjects fed background cholesterol-free formula diets with 40% of calories as fat. Each test meal consisted of a breakfast into which was incorporated scrambled egg yolk containing 300-500 mg of cholesterol and [4-(14)C]cholesterol (3-22 muCi), either naturally incorporated into the yolk cholesterol by previous isotope injection into the laying hen or added in peanut oil to the yolk of the test breakfast. In some instances [1alpha-(3)H]cholesterol was the radioactive marker. The radioactivity of the fecal neutral sterol fraction was determined in daily stool samples for the next 7 days to provide an estimate of unabsorbed dietary cholesterol. The amount of absorbed and reexcreted labeled cholesterol proved negligible. Most unabsorbed dietary cholesterol appeared in the stool on the second or third day after the meal, and 95% or more was recovered in the stool by 6 days. Plasma specific activity curves were usually maximal at 48 h. Normal subjects absorbed 44.5+/-9.3 (SD) of the administered cholesterol (range 25.9-60.3). Hypercholesterolemics absorbed the same percentage of cholesterol as normals: 47.6+/-12.6% (range 29.3-67.3). Absorption was similar whether the radiolabeled cholesterol was added to egg yolk or naturally incorporated in it (42.1+/-9.3 vs. 48.9+/-9.8%). Six normal subjects were fed a cholesterol-free formula for 4 wk, and then different amounts of cholesterol (110-610 mg/day) were added for another 4 wk. At the end of each period, single test meals containing either 110, 310, or 610 mg of cholesterol and [1alpha-(3)H]cholesterol were administered. Cholesterol absorption was 42.3+/-6.0% and 45.4+/-8.3% for the two dietary periods, respectively. The absolute cholesterol absorption was linearly related to the amount of cholesterol in the test meal, and absorption was not affected by background diets high or low in cholesterol content." @default.
• W2018231544 created "2016-06-24" @default.
• W2018231544 creator A5010372404 @default.
• W2018231544 creator A5042403562 @default.
• W2018231544 date "1974-04-01" @default.
• W2018231544 modified "2023-09-23" @default.
• W2018231544 title "The Intestinal Absorption of Dietary Cholesterol by Hypercholesterolemic (Type II) and Normocholesterolemic Humans" @default.
• W2018231544 cites W1513741126 @default.
• W2018231544 cites W1521819039 @default.
• W2018231544 cites W1813859694 @default.
• W2018231544 cites W1979865783 @default.
• W2018231544 cites W1983037306 @default.
• W2018231544 cites W2014504970 @default.
• W2018231544 cites W2040840603 @default.
• W2018231544 cites W2108478964 @default.
• W2018231544 cites W2110871647 @default.
• W2018231544 cites W2114807641 @default.
• W2018231544 cites W2143992413 @default.
• W2018231544 cites W2147973062 @default.
• W2018231544 cites W2156023251 @default.
• W2018231544 cites W2162719733 @default.
• W2018231544 cites W2168526937 @default.
• W2018231544 cites W2182413963 @default.
• W2018231544 cites W2187187756 @default.
• W2018231544 cites W2298917449 @default.
• W2018231544 cites W2298954654 @default.
• W2018231544 cites W2314766391 @default.
• W2018231544 cites W2329759212 @default.
• W2018231544 cites W2333914839 @default.
• W2018231544 cites W2433705576 @default.
• W2018231544 cites W2465382919 @default.
• W2018231544 cites W2413293383 @default.
• W2018231544 doi "https://doi.org/10.1172/jci107643" @default.
• W2018231544 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/333091" @default.
• W2018231544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4815075" @default.
• W2018231544 hasPublicationYear "1974" @default.
• W2018231544 type Work @default.
• W2018231544 sameAs 2018231544 @default.
• W2018231544 citedByCount "99" @default.
• W2018231544 countsByYear W20182315442012 @default.
• W2018231544 countsByYear W20182315442013 @default.
• W2018231544 countsByYear W20182315442018 @default.
• W2018231544 countsByYear W20182315442021 @default.
• W2018231544 countsByYear W20182315442023 @default.
• W2018231544 crossrefType "journal-article" @default.
• W2018231544 hasAuthorship W2018231544A5010372404 @default.
• W2018231544 hasAuthorship W2018231544A5042403562 @default.
• W2018231544 hasBestOaLocation W20182315441 @default.
• W2018231544 hasConcept C121332964 @default.
• W2018231544 hasConcept C125287762 @default.
• W2018231544 hasConcept C126322002 @default.
• W2018231544 hasConcept C134018914 @default.
• W2018231544 hasConcept C151730666 @default.
• W2018231544 hasConcept C185592680 @default.
• W2018231544 hasConcept C24890656 @default.
• W2018231544 hasConcept C2778163477 @default.
• W2018231544 hasConcept C2778345441 @default.
• W2018231544 hasConcept C2778718757 @default.
• W2018231544 hasConcept C2781321622 @default.
• W2018231544 hasConcept C2909484148 @default.
• W2018231544 hasConcept C31903555 @default.
• W2018231544 hasConcept C40438245 @default.
• W2018231544 hasConcept C55493867 @default.
• W2018231544 hasConcept C61716771 @default.
• W2018231544 hasConcept C71924100 @default.
• W2018231544 hasConcept C86803240 @default.
• W2018231544 hasConceptScore W2018231544C121332964 @default.
• W2018231544 hasConceptScore W2018231544C125287762 @default.
• W2018231544 hasConceptScore W2018231544C126322002 @default.
• W2018231544 hasConceptScore W2018231544C134018914 @default.
• W2018231544 hasConceptScore W2018231544C151730666 @default.
• W2018231544 hasConceptScore W2018231544C185592680 @default.
• W2018231544 hasConceptScore W2018231544C24890656 @default.
• W2018231544 hasConceptScore W2018231544C2778163477 @default.
• W2018231544 hasConceptScore W2018231544C2778345441 @default.
• W2018231544 hasConceptScore W2018231544C2778718757 @default.
• W2018231544 hasConceptScore W2018231544C2781321622 @default.
• W2018231544 hasConceptScore W2018231544C2909484148 @default.
• W2018231544 hasConceptScore W2018231544C31903555 @default.
• W2018231544 hasConceptScore W2018231544C40438245 @default.
• W2018231544 hasConceptScore W2018231544C55493867 @default.
• W2018231544 hasConceptScore W2018231544C61716771 @default.
• W2018231544 hasConceptScore W2018231544C71924100 @default.
• W2018231544 hasConceptScore W2018231544C86803240 @default.
• W2018231544 hasIssue "4" @default.
• W2018231544 hasLocation W20182315441 @default.
• W2018231544 hasLocation W20182315442 @default.
• W2018231544 hasLocation W20182315443 @default.
• W2018231544 hasLocation W20182315444 @default.
• W2018231544 hasOpenAccess W2018231544 @default.
• W2018231544 hasPrimaryLocation W20182315441 @default.
• W2018231544 hasRelatedWork W1964575766 @default.
• W2018231544 hasRelatedWork W1967470628 @default.
• W2018231544 hasRelatedWork W1971439187 @default.
• W2018231544 hasRelatedWork W2035331946 @default.
• W2018231544 hasRelatedWork W2090180473 @default.
• W2018231544 hasRelatedWork W2096204303 @default.
• W2018231544 hasRelatedWork W2098180171 @default.

• next