Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018235831> ?p ?o ?g. }
- W2018235831 endingPage "828" @default.
- W2018235831 startingPage "820" @default.
- W2018235831 abstract "Aging, a multifactorial process of enormous complexity is characterized by impairment of physio-chemical and biological aspects of cellular functions. It is closely associated with increased free radical production, which situation ultimately leads to devastation of normal cell function and membrane integrity. The present study was aimed to determine the effect of proanthocyanidins rich grape seed extract (GSP) on membrane surface charge density in erythrocytes during animal age associated oxidative stress. GSP (100 mg/day/kg body weight) was administered orally for 15 and 30 days to young and aged rats. Significant decrease in surface charge levels with concomitant increase in protein carbonyls and decrease in glycoprotein, antioxidants status was noted in erythrocytes of aged rats when compared with young rat erythrocytes. Duration dependent supplementation of GSP increased the erythrocyte surface charge density to near normalcy in aged rats. Decrease in protein carbonyls level and increase in glycoproteins as well as antioxidant status was observed in aged rat erythrocytes on GSP treatment. Thus, from our results, we conclude that GSP is an effective anti-aging drug in preventing the oxidative stress associated loss of membrane surface charge, which thereby maintains the erythrocyte membrane integrity and functions in elderly." @default.
- W2018235831 created "2016-06-24" @default.
- W2018235831 creator A5006788831 @default.
- W2018235831 creator A5014817201 @default.
- W2018235831 creator A5022530149 @default.
- W2018235831 creator A5046120332 @default.
- W2018235831 date "2005-10-01" @default.
- W2018235831 modified "2023-09-23" @default.
- W2018235831 title "Age associated changes in erythrocyte membrane surface charge: Modulatory role of grape seed proanthocyanidins" @default.
- W2018235831 cites W1197809209 @default.
- W2018235831 cites W1487193306 @default.
- W2018235831 cites W1508162082 @default.
- W2018235831 cites W1535848596 @default.
- W2018235831 cites W1559601107 @default.
- W2018235831 cites W1580023435 @default.
- W2018235831 cites W1581414347 @default.
- W2018235831 cites W1657423079 @default.
- W2018235831 cites W1768247331 @default.
- W2018235831 cites W1775749144 @default.
- W2018235831 cites W195431704 @default.
- W2018235831 cites W1965551629 @default.
- W2018235831 cites W1972070256 @default.
- W2018235831 cites W1974068481 @default.
- W2018235831 cites W1982144156 @default.
- W2018235831 cites W1982494817 @default.
- W2018235831 cites W1988740018 @default.
- W2018235831 cites W1994540520 @default.
- W2018235831 cites W2003835077 @default.
- W2018235831 cites W2007064404 @default.
- W2018235831 cites W2009112923 @default.
- W2018235831 cites W2022779386 @default.
- W2018235831 cites W2035299415 @default.
- W2018235831 cites W2036678992 @default.
- W2018235831 cites W204706947 @default.
- W2018235831 cites W2049085950 @default.
- W2018235831 cites W2049314157 @default.
- W2018235831 cites W2052664734 @default.
- W2018235831 cites W2057431968 @default.
- W2018235831 cites W2060194897 @default.
- W2018235831 cites W2069132215 @default.
- W2018235831 cites W2070446507 @default.
- W2018235831 cites W2073336057 @default.
- W2018235831 cites W2078198580 @default.
- W2018235831 cites W2086959952 @default.
- W2018235831 cites W2088866343 @default.
- W2018235831 cites W2089251026 @default.
- W2018235831 cites W2092635604 @default.
- W2018235831 cites W2097273693 @default.
- W2018235831 cites W2133971230 @default.
- W2018235831 cites W2164662203 @default.
- W2018235831 cites W2166511953 @default.
- W2018235831 cites W2168526937 @default.
- W2018235831 cites W2172213806 @default.
- W2018235831 cites W2189259967 @default.
- W2018235831 cites W2209770937 @default.
- W2018235831 cites W2261445871 @default.
- W2018235831 cites W2291196898 @default.
- W2018235831 cites W2341370789 @default.
- W2018235831 cites W2407534192 @default.
- W2018235831 cites W2408707711 @default.
- W2018235831 cites W2416297360 @default.
- W2018235831 cites W2467449772 @default.
- W2018235831 cites W2489585253 @default.
- W2018235831 cites W57880438 @default.
- W2018235831 doi "https://doi.org/10.1016/j.exger.2005.07.008" @default.
- W2018235831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16139463" @default.
- W2018235831 hasPublicationYear "2005" @default.
- W2018235831 type Work @default.
- W2018235831 sameAs 2018235831 @default.
- W2018235831 citedByCount "43" @default.
- W2018235831 countsByYear W20182358312012 @default.
- W2018235831 countsByYear W20182358312013 @default.
- W2018235831 countsByYear W20182358312014 @default.
- W2018235831 countsByYear W20182358312015 @default.
- W2018235831 countsByYear W20182358312016 @default.
- W2018235831 countsByYear W20182358312017 @default.
- W2018235831 countsByYear W20182358312018 @default.
- W2018235831 countsByYear W20182358312019 @default.
- W2018235831 countsByYear W20182358312020 @default.
- W2018235831 countsByYear W20182358312021 @default.
- W2018235831 countsByYear W20182358312022 @default.
- W2018235831 countsByYear W20182358312023 @default.
- W2018235831 crossrefType "journal-article" @default.
- W2018235831 hasAuthorship W2018235831A5006788831 @default.
- W2018235831 hasAuthorship W2018235831A5014817201 @default.
- W2018235831 hasAuthorship W2018235831A5022530149 @default.
- W2018235831 hasAuthorship W2018235831A5046120332 @default.
- W2018235831 hasConcept C108625454 @default.
- W2018235831 hasConcept C12554922 @default.
- W2018235831 hasConcept C126322002 @default.
- W2018235831 hasConcept C134018914 @default.
- W2018235831 hasConcept C144647389 @default.
- W2018235831 hasConcept C185592680 @default.
- W2018235831 hasConcept C2776151105 @default.
- W2018235831 hasConcept C2776557347 @default.
- W2018235831 hasConcept C2778004101 @default.
- W2018235831 hasConcept C2993443003 @default.
- W2018235831 hasConcept C41625074 @default.