Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018242013> ?p ?o ?g. }
- W2018242013 endingPage "220" @default.
- W2018242013 startingPage "213" @default.
- W2018242013 abstract "To determine the molecular mechanisms of diabetes-related changes in the expression of GLUT-1 in cerebral tissue, streptozotocin-induced diabetic rats and vehicle injected controls were studied after 4 weeks of diabetes. The GLUT-1 mass in cerebral microvessels was reduced in diabetic rats by approximately 38% (P < 0.01). The GLUT-1 concentration in insulin-treated diabetic group was not significantly different from controls. The GLUT-1 mRNA content of cerebral tissue in diabetic rats (0.064 +/- 0.007) was significantly reduced compared to control rats (0.122 +/- 0.011) or insulin-treated diabetic rats (0.122 +/- 0.015) P < 0.01. The in vitro translation of GLUT-1 mRNA of diabetic rats (0.793 +/- 0.047 arbitrary units) was also significantly lower than that in control rats (1.403 +/- 0.153) P < 0.01 or insulin-treated diabetic rats. (1.124 +/- 0.083) P < 0.01. These changes occurred in asssociation with a reduction in poly (A) tail length of GLUT-1 mRNA which decreased from a control value of 200-350 nt to only 50-100 nt in diabetic rats. Shortening of poly (A) tail of mRNAs is a novel mechanism of diabetes-related changes in the expression of specific genes which are regulated at a translational level." @default.
- W2018242013 created "2016-06-24" @default.
- W2018242013 creator A5010733907 @default.
- W2018242013 creator A5075060708 @default.
- W2018242013 creator A5091546736 @default.
- W2018242013 date "1997-04-01" @default.
- W2018242013 modified "2023-09-26" @default.
- W2018242013 title "Shortening of poly (A) tail of glucose transporter — one mRNA in experimental diabetes mellitus" @default.
- W2018242013 cites W1004388750 @default.
- W2018242013 cites W1775749144 @default.
- W2018242013 cites W1966742367 @default.
- W2018242013 cites W1967064176 @default.
- W2018242013 cites W1969225446 @default.
- W2018242013 cites W1970403529 @default.
- W2018242013 cites W1988393624 @default.
- W2018242013 cites W1989438185 @default.
- W2018242013 cites W1992407119 @default.
- W2018242013 cites W2000061885 @default.
- W2018242013 cites W2005671724 @default.
- W2018242013 cites W2005991627 @default.
- W2018242013 cites W2011836510 @default.
- W2018242013 cites W2015628327 @default.
- W2018242013 cites W2027562034 @default.
- W2018242013 cites W2029016362 @default.
- W2018242013 cites W2030629284 @default.
- W2018242013 cites W2032368489 @default.
- W2018242013 cites W2035037063 @default.
- W2018242013 cites W2038916245 @default.
- W2018242013 cites W2044087440 @default.
- W2018242013 cites W2045462467 @default.
- W2018242013 cites W2050233629 @default.
- W2018242013 cites W2060616628 @default.
- W2018242013 cites W2067064841 @default.
- W2018242013 cites W2077077811 @default.
- W2018242013 cites W2091625139 @default.
- W2018242013 cites W2093311159 @default.
- W2018242013 cites W2095950646 @default.
- W2018242013 cites W2096996169 @default.
- W2018242013 cites W2100837269 @default.
- W2018242013 cites W2101108802 @default.
- W2018242013 cites W2105193126 @default.
- W2018242013 cites W2111127316 @default.
- W2018242013 cites W2160547691 @default.
- W2018242013 cites W2161160353 @default.
- W2018242013 doi "https://doi.org/10.1016/s0006-8993(97)00073-5" @default.
- W2018242013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9134978" @default.
- W2018242013 hasPublicationYear "1997" @default.
- W2018242013 type Work @default.
- W2018242013 sameAs 2018242013 @default.
- W2018242013 citedByCount "14" @default.
- W2018242013 countsByYear W20182420132012 @default.
- W2018242013 countsByYear W20182420132016 @default.
- W2018242013 countsByYear W20182420132021 @default.
- W2018242013 crossrefType "journal-article" @default.
- W2018242013 hasAuthorship W2018242013A5010733907 @default.
- W2018242013 hasAuthorship W2018242013A5075060708 @default.
- W2018242013 hasAuthorship W2018242013A5091546736 @default.
- W2018242013 hasConcept C104317684 @default.
- W2018242013 hasConcept C105580179 @default.
- W2018242013 hasConcept C126322002 @default.
- W2018242013 hasConcept C134018914 @default.
- W2018242013 hasConcept C161573976 @default.
- W2018242013 hasConcept C185592680 @default.
- W2018242013 hasConcept C2779280383 @default.
- W2018242013 hasConcept C2779306644 @default.
- W2018242013 hasConcept C55493867 @default.
- W2018242013 hasConcept C555293320 @default.
- W2018242013 hasConcept C71924100 @default.
- W2018242013 hasConceptScore W2018242013C104317684 @default.
- W2018242013 hasConceptScore W2018242013C105580179 @default.
- W2018242013 hasConceptScore W2018242013C126322002 @default.
- W2018242013 hasConceptScore W2018242013C134018914 @default.
- W2018242013 hasConceptScore W2018242013C161573976 @default.
- W2018242013 hasConceptScore W2018242013C185592680 @default.
- W2018242013 hasConceptScore W2018242013C2779280383 @default.
- W2018242013 hasConceptScore W2018242013C2779306644 @default.
- W2018242013 hasConceptScore W2018242013C55493867 @default.
- W2018242013 hasConceptScore W2018242013C555293320 @default.
- W2018242013 hasConceptScore W2018242013C71924100 @default.
- W2018242013 hasIssue "1-2" @default.
- W2018242013 hasLocation W20182420131 @default.
- W2018242013 hasLocation W20182420132 @default.
- W2018242013 hasOpenAccess W2018242013 @default.
- W2018242013 hasPrimaryLocation W20182420131 @default.
- W2018242013 hasRelatedWork W2003485540 @default.
- W2018242013 hasRelatedWork W2006513370 @default.
- W2018242013 hasRelatedWork W2037205718 @default.
- W2018242013 hasRelatedWork W2044988659 @default.
- W2018242013 hasRelatedWork W2096420073 @default.
- W2018242013 hasRelatedWork W2112457773 @default.
- W2018242013 hasRelatedWork W2131147582 @default.
- W2018242013 hasRelatedWork W2187001057 @default.
- W2018242013 hasRelatedWork W2410784692 @default.
- W2018242013 hasRelatedWork W2434287781 @default.
- W2018242013 hasVolume "754" @default.
- W2018242013 isParatext "false" @default.
- W2018242013 isRetracted "false" @default.
- W2018242013 magId "2018242013" @default.