FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018257579> ?p ?o ?g. }

• W2018257579 endingPage "144" @default.
• W2018257579 startingPage "137" @default.
• W2018257579 abstract "Summary: With the improved therapy for acute diarrhea, persistent diarrhea (> 14 days) is emerging as a major problem in developing countries. However, the etiologies and pathogenesis of persistent diarrhea remain poorly understood. We conducted a prospective case-control study in children <3 years old presenting to the hospital with persistent diarrhea in Fortaleza, Brazil. Over the study period (August 1988 to March 1991), 56 children seen with persistent diarrhea, 52 children seen with acute diarrhea, and 42 controls attending the same hospital/clinic for illnesses other than diarrhea were enrolled. A potential pathogen was found in 91% of children with persistent diarrhea and 90% of those with acute diarrhea versus 45% of controls (both p‘s < 0.01). Thirty-four percent of persistent (19/56) and 38% of acute (20/52) diarrhea cases versus 2% (1/42) of controls (both p’s < 0.01) had multiple pathogens. Enteroaggregative Escherichia coli (EAggEC) were found in 68% (38/56) of children with persistent diarrhea versus 31% (13/42) of controls (p < 0.01) and in 46% (24/52) of those with acute diarrhea. Furthermore, when the EAggEC were subdivided into aggregative adherence (AA) gene probe positive (18/56; 32%) and negative (20/56; 36%), both subgroups were still significantly different from controls [6/42 (14%) and 7/42 (17%), respectively; both p‘s < 0.05]. EAggEC were the sole pathogen in 17 of 56 (30%) of patients with persistent diarrhea [vs. 11/94 (11.7%) in those with acute diarrhea and controls; p < 0.01], and AA gene probe-positive EAggEC were the sole pathogen in 20% of children with persistent diarrhea, whereas only 6% of those with acute diarrhea and 7% of controls had AA probe-positive E. coli (persistent diarrhea vs. acute diarrhea and controls; p < 0.03) Cryptosporidia were found in 25% (14/56) of children with persistent diarrhea (vs. 5% of controls; p < 0.02). Of 32 children with persistent diarrhea who had quantitative small bowel cultures, 13 (41%) had ≥ 104/ml EAggEC (2 had AA probe-positive EAggEC) in the upper small bowel. Of 10 EAggEC isolated from the small bowel of seven patients with persistent diarrhea, 6 significantly colonized and caused diarrhea in the rabbit-reversible ileal tie model. Both AA gene probe-positive and AA gene probe-negative EAggEC and Cryptosporidium are important potential pathogens in young children with persistent diarrhea and warrant further study to improve our understanding of their pathogenesis and control." @default.
• W2018257579 created "2016-06-24" @default.
• W2018257579 creator A5006872102 @default.
• W2018257579 creator A5031543871 @default.
• W2018257579 creator A5045149586 @default.
• W2018257579 creator A5071031273 @default.
• W2018257579 creator A5079606848 @default.
• W2018257579 date "1995-08-01" @default.
• W2018257579 modified "2023-10-18" @default.
• W2018257579 title "Etiology and Epidemiology of Persistent Diarrhea in Northeastern Brazil" @default.
• W2018257579 doi "https://doi.org/10.1097/00005176-199508000-00003" @default.
• W2018257579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7472898" @default.
• W2018257579 hasPublicationYear "1995" @default.
• W2018257579 type Work @default.
• W2018257579 sameAs 2018257579 @default.
• W2018257579 citedByCount "122" @default.
• W2018257579 countsByYear W20182575792012 @default.
• W2018257579 countsByYear W20182575792013 @default.
• W2018257579 countsByYear W20182575792014 @default.
• W2018257579 countsByYear W20182575792015 @default.
• W2018257579 countsByYear W20182575792016 @default.
• W2018257579 countsByYear W20182575792017 @default.
• W2018257579 countsByYear W20182575792018 @default.
• W2018257579 countsByYear W20182575792019 @default.
• W2018257579 countsByYear W20182575792020 @default.
• W2018257579 countsByYear W20182575792021 @default.
• W2018257579 countsByYear W20182575792023 @default.
• W2018257579 crossrefType "journal-article" @default.
• W2018257579 hasAuthorship W2018257579A5006872102 @default.
• W2018257579 hasAuthorship W2018257579A5031543871 @default.
• W2018257579 hasAuthorship W2018257579A5045149586 @default.
• W2018257579 hasAuthorship W2018257579A5071031273 @default.
• W2018257579 hasAuthorship W2018257579A5079606848 @default.
• W2018257579 hasBestOaLocation W20182575791 @default.
• W2018257579 hasConcept C104317684 @default.
• W2018257579 hasConcept C107130276 @default.
• W2018257579 hasConcept C126322002 @default.
• W2018257579 hasConcept C137627325 @default.
• W2018257579 hasConcept C187212893 @default.
• W2018257579 hasConcept C188816634 @default.
• W2018257579 hasConcept C203014093 @default.
• W2018257579 hasConcept C2776460866 @default.
• W2018257579 hasConcept C2777587559 @default.
• W2018257579 hasConcept C2778910516 @default.
• W2018257579 hasConcept C2779802037 @default.
• W2018257579 hasConcept C3019834005 @default.
• W2018257579 hasConcept C547475151 @default.
• W2018257579 hasConcept C55493867 @default.
• W2018257579 hasConcept C71924100 @default.
• W2018257579 hasConcept C86803240 @default.
• W2018257579 hasConcept C90924648 @default.
• W2018257579 hasConceptScore W2018257579C104317684 @default.
• W2018257579 hasConceptScore W2018257579C107130276 @default.
• W2018257579 hasConceptScore W2018257579C126322002 @default.
• W2018257579 hasConceptScore W2018257579C137627325 @default.
• W2018257579 hasConceptScore W2018257579C187212893 @default.
• W2018257579 hasConceptScore W2018257579C188816634 @default.
• W2018257579 hasConceptScore W2018257579C203014093 @default.
• W2018257579 hasConceptScore W2018257579C2776460866 @default.
• W2018257579 hasConceptScore W2018257579C2777587559 @default.
• W2018257579 hasConceptScore W2018257579C2778910516 @default.
• W2018257579 hasConceptScore W2018257579C2779802037 @default.
• W2018257579 hasConceptScore W2018257579C3019834005 @default.
• W2018257579 hasConceptScore W2018257579C547475151 @default.
• W2018257579 hasConceptScore W2018257579C55493867 @default.
• W2018257579 hasConceptScore W2018257579C71924100 @default.
• W2018257579 hasConceptScore W2018257579C86803240 @default.
• W2018257579 hasConceptScore W2018257579C90924648 @default.
• W2018257579 hasIssue "2" @default.
• W2018257579 hasLocation W20182575791 @default.
• W2018257579 hasLocation W20182575792 @default.
• W2018257579 hasLocation W20182575793 @default.
• W2018257579 hasOpenAccess W2018257579 @default.
• W2018257579 hasPrimaryLocation W20182575791 @default.
• W2018257579 hasRelatedWork W180298543 @default.
• W2018257579 hasRelatedWork W2018257579 @default.
• W2018257579 hasRelatedWork W2024566737 @default.
• W2018257579 hasRelatedWork W2042097983 @default.
• W2018257579 hasRelatedWork W2089958827 @default.
• W2018257579 hasRelatedWork W2091837008 @default.
• W2018257579 hasRelatedWork W2166449161 @default.
• W2018257579 hasRelatedWork W2283321188 @default.
• W2018257579 hasRelatedWork W2332504426 @default.
• W2018257579 hasRelatedWork W2420642637 @default.
• W2018257579 hasVolume "21" @default.
• W2018257579 isParatext "false" @default.
• W2018257579 isRetracted "false" @default.
• W2018257579 magId "2018257579" @default.
• W2018257579 workType "article" @default.