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- W2018258495 abstract "<h3>Objective:</h3> The current study sought to describe the functional profiles of patients with early-stage progressive supranuclear palsy (PSP) in a large prospective, multisite study. <h3>Methods:</h3> Using data from 202 individuals meeting criteria for clinically definite or probable PSP, 3 functional scales were examined. Functional scores were then compared to measures of motor, cognition, and psychiatric symptoms. <h3>Results:</h3> Functional disability was high in early-stage PSP, with 100% of patients having less than perfect scores on all functional scales. Whereas functional scores tended not to be related to cognition or psychiatric symptoms, they were strongly related to motoric ratings. <h3>Conclusions:</h3> Both clinically and in research settings, the definition of functional intactness/impairment has important implications. Future studies should examine if functional impairment is this high in PSP or if new scales of functional abilities need to be developed for this condition." @default.
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- W2018258495 date "2013-01-09" @default.
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- W2018258495 title "Functional impairment in progressive supranuclear palsy" @default.
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- W2018258495 doi "https://doi.org/10.1212/wnl.0b013e31827f0859" @default.
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