Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018281087> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2018281087 endingPage "68" @default.
- W2018281087 startingPage "61" @default.
- W2018281087 abstract "We have tested the proposal that the level of silver banding in leukemic cells of Ph1 + chronic granulocytic leukemia (CGL) patients increases as the disease progresses. Blood and/or bone marrow cells from 14 patients were cultured for 24 hr before banding. In all but one case, there were two populations of mitoses, those with silver bands on their nucleolar organizing regions (NORs) and those without. The percentage of cells that banded was higher, on average, in cultures from 7 patients in blastic transformation (80%) than in 8 chronic cases (36%) or in one accelerated phase (49%). Also, the mean number of NORs stained in banded cells was higher in blastic phase (6.9) compared with chronic phase cells (4.4). Hyperdiploid cell lines were present in four cases of myeloblastic transformation. All such cells were silver banded, and the mean fraction of NORs banded in them was relatively high. An increase in silver banding with time was shown in two of the patients. It seems that silver banding does increase in CGL cells as the disease progresses. This may arise either through an increase in the rate of ribosomal RNA synthesis in leukemic cells present in the blastic phase or possibly by a decrease in the rate of degradation (or processing) of newly synthesized rRNA." @default.
- W2018281087 created "2016-06-24" @default.
- W2018281087 creator A5001321529 @default.
- W2018281087 creator A5022662848 @default.
- W2018281087 creator A5038250342 @default.
- W2018281087 creator A5067693286 @default.
- W2018281087 date "1984-01-01" @default.
- W2018281087 modified "2023-09-27" @default.
- W2018281087 title "Silver bands in chronic granulocytic leukemia: I. Increased banding associated with blastic transformation" @default.
- W2018281087 cites W1543585939 @default.
- W2018281087 cites W1970940470 @default.
- W2018281087 cites W1999826365 @default.
- W2018281087 cites W2003990599 @default.
- W2018281087 cites W2021017070 @default.
- W2018281087 cites W2028111700 @default.
- W2018281087 cites W2029098686 @default.
- W2018281087 cites W2050389863 @default.
- W2018281087 cites W2059549678 @default.
- W2018281087 cites W2066749872 @default.
- W2018281087 cites W2101301520 @default.
- W2018281087 doi "https://doi.org/10.1016/0165-4608(84)90099-2" @default.
- W2018281087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6580944" @default.
- W2018281087 hasPublicationYear "1984" @default.
- W2018281087 type Work @default.
- W2018281087 sameAs 2018281087 @default.
- W2018281087 citedByCount "8" @default.
- W2018281087 crossrefType "journal-article" @default.
- W2018281087 hasAuthorship W2018281087A5001321529 @default.
- W2018281087 hasAuthorship W2018281087A5022662848 @default.
- W2018281087 hasAuthorship W2018281087A5038250342 @default.
- W2018281087 hasAuthorship W2018281087A5067693286 @default.
- W2018281087 hasConcept C104317684 @default.
- W2018281087 hasConcept C153911025 @default.
- W2018281087 hasConcept C203014093 @default.
- W2018281087 hasConcept C204241405 @default.
- W2018281087 hasConcept C25330733 @default.
- W2018281087 hasConcept C2778461978 @default.
- W2018281087 hasConcept C2779378344 @default.
- W2018281087 hasConcept C2910168157 @default.
- W2018281087 hasConcept C54355233 @default.
- W2018281087 hasConcept C67905577 @default.
- W2018281087 hasConcept C86803240 @default.
- W2018281087 hasConcept C93304396 @default.
- W2018281087 hasConceptScore W2018281087C104317684 @default.
- W2018281087 hasConceptScore W2018281087C153911025 @default.
- W2018281087 hasConceptScore W2018281087C203014093 @default.
- W2018281087 hasConceptScore W2018281087C204241405 @default.
- W2018281087 hasConceptScore W2018281087C25330733 @default.
- W2018281087 hasConceptScore W2018281087C2778461978 @default.
- W2018281087 hasConceptScore W2018281087C2779378344 @default.
- W2018281087 hasConceptScore W2018281087C2910168157 @default.
- W2018281087 hasConceptScore W2018281087C54355233 @default.
- W2018281087 hasConceptScore W2018281087C67905577 @default.
- W2018281087 hasConceptScore W2018281087C86803240 @default.
- W2018281087 hasConceptScore W2018281087C93304396 @default.
- W2018281087 hasIssue "1" @default.
- W2018281087 hasLocation W20182810871 @default.
- W2018281087 hasLocation W20182810872 @default.
- W2018281087 hasOpenAccess W2018281087 @default.
- W2018281087 hasPrimaryLocation W20182810871 @default.
- W2018281087 hasRelatedWork W122023798 @default.
- W2018281087 hasRelatedWork W184468193 @default.
- W2018281087 hasRelatedWork W1995007817 @default.
- W2018281087 hasRelatedWork W2058524685 @default.
- W2018281087 hasRelatedWork W2093723960 @default.
- W2018281087 hasRelatedWork W2141579576 @default.
- W2018281087 hasRelatedWork W2411272799 @default.
- W2018281087 hasRelatedWork W2419211028 @default.
- W2018281087 hasRelatedWork W3022966388 @default.
- W2018281087 hasRelatedWork W4240012924 @default.
- W2018281087 hasVolume "11" @default.
- W2018281087 isParatext "false" @default.
- W2018281087 isRetracted "false" @default.
- W2018281087 magId "2018281087" @default.
- W2018281087 workType "article" @default.