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- W2018288785 abstract "Genomics has become a ground-breaking field in all areas of the life sciences. The advanced genomics and the development of high-throughput techniques have lately provided insight into whole-genome characterization of a wide range of organisms. In the post-genomic era, new technologies have revealed an outbreak of prerequisite genomic sequences and supporting data to understand genome wide functional regulation of gene expression and metabolic pathways reconstruction. However, the availability of this plethora of genomic data presents a significant challenge for storage, analyses and data management. Analysis of this mega-data requires the development and application of novel bioinformatics tools that must include unified functional annotation, structural search, and comprehensive analysis and identification of new genes in a wide range of species with fully sequenced genomes. In addition, generation of systematically and syntactically unambiguous nomenclature systems for genomic data across species is a crucial task. Such systems are necessary for adequate handling genetic information in the context of comparative functional genomics. In this paper, we provide an overview of major advances in bioinformatics and computational biology in genome sequencing and next-generation sequence data analysis. We focus on their potential applications for efficient collection, storage, and analysis of genetic data/information from a wide range of gene banks. We also discuss the importance of establishing a unified nomenclature system through a functional and structural genomics approach." @default.
- W2018288785 created "2016-06-24" @default.
- W2018288785 creator A5015319536 @default.
- W2018288785 creator A5025695630 @default.
- W2018288785 creator A5027849577 @default.
- W2018288785 creator A5091879686 @default.
- W2018288785 date "2013-01-01" @default.
- W2018288785 modified "2023-10-15" @default.
- W2018288785 title "Genome sequencing and next-generation sequence data analysis: A comprehensive compilation of bioinformatics tools and databases" @default.
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