FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018302586> ?p ?o ?g. }

• W2018302586 endingPage "38" @default.
• W2018302586 startingPage "33" @default.
• W2018302586 abstract "Many diseases are easier to treat and control when detected at an early stage of disease progression. Often, disease-related antigens or biomarkers are shed from the primary site and present in the blood. Unfortunately, there are very few tests capable of detecting these rare biomarkers in the blood. A blood test would be very useful to diagnose the disease earlier, monitor effectiveness of treatments, predict recurrence, and monitor recurrence. There is certainly a need to develop assays that are ultra-sensitive, non-invasive, and high-throughput. Here we describe several highly sensitive immunological assays we have developed to detect rare serum antigens. Initially we created an assay named immuno-detection amplified by T7 RNA polymerase (IDAT). To enhance the effectiveness and streamline the procedure, this assay was amended to the facile amplification system termed fluorescent amplification catalyzed by T7 polymerase technique (FACTT). These assays have been used to analyze the tumor antigen HER2 and the prion protein PrPSc. They can also be applied to other tumor markers or antigens from a variety of diseases such as cardiovascular disease, rheumatoid arthritis, Alzheimer's disease, Parkinson's disease, and hepatitis. These tests are not limited to testing only serum, but may also be applicable to detecting biomarkers in tissue, saliva, urine, cerebrospinal fluid, etc. Clearly, the FACTT-based technology represents an important step in the detection of rare molecules in fluids or tissues for a variety of diseases." @default.
• W2018302586 created "2016-06-24" @default.
• W2018302586 creator A5009350001 @default.
• W2018302586 creator A5017857303 @default.
• W2018302586 creator A5042586488 @default.
• W2018302586 creator A5063558357 @default.
• W2018302586 date "2008-09-01" @default.
• W2018302586 modified "2023-10-11" @default.
• W2018302586 title "Non-invasive, ultra-sensitive, high-throughput assays to quantify rare biomarkers in the blood" @default.
• W2018302586 cites W1545824483 @default.
• W2018302586 cites W1553401382 @default.
• W2018302586 cites W1901376003 @default.
• W2018302586 cites W1965919284 @default.
• W2018302586 cites W1967261289 @default.
• W2018302586 cites W1973165168 @default.
• W2018302586 cites W1974681241 @default.
• W2018302586 cites W1991766587 @default.
• W2018302586 cites W1992666783 @default.
• W2018302586 cites W1996939391 @default.
• W2018302586 cites W2001575993 @default.
• W2018302586 cites W2002830509 @default.
• W2018302586 cites W2003231014 @default.
• W2018302586 cites W2005084132 @default.
• W2018302586 cites W2006813546 @default.
• W2018302586 cites W2013679718 @default.
• W2018302586 cites W2019956094 @default.
• W2018302586 cites W2022392367 @default.
• W2018302586 cites W2023529808 @default.
• W2018302586 cites W2035004702 @default.
• W2018302586 cites W2035949167 @default.
• W2018302586 cites W2036645353 @default.
• W2018302586 cites W2037509330 @default.
• W2018302586 cites W2038398273 @default.
• W2018302586 cites W2041462833 @default.
• W2018302586 cites W2042051621 @default.
• W2018302586 cites W2043998320 @default.
• W2018302586 cites W2046633236 @default.
• W2018302586 cites W2056581335 @default.
• W2018302586 cites W2065190847 @default.
• W2018302586 cites W2069044141 @default.
• W2018302586 cites W2071130163 @default.
• W2018302586 cites W2077194187 @default.
• W2018302586 cites W2079722759 @default.
• W2018302586 cites W2095156669 @default.
• W2018302586 cites W2096335059 @default.
• W2018302586 cites W2103270514 @default.
• W2018302586 cites W2104586872 @default.
• W2018302586 cites W2106118263 @default.
• W2018302586 cites W2115759102 @default.
• W2018302586 cites W2118652254 @default.
• W2018302586 cites W2121777852 @default.
• W2018302586 cites W2129466993 @default.
• W2018302586 cites W2138468217 @default.
• W2018302586 cites W2148130200 @default.
• W2018302586 cites W2154713296 @default.
• W2018302586 cites W2162119312 @default.
• W2018302586 cites W2165147575 @default.
• W2018302586 cites W2318017958 @default.
• W2018302586 cites W2340128174 @default.
• W2018302586 cites W4235767534 @default.
• W2018302586 cites W4241057416 @default.
• W2018302586 cites W4252594516 @default.
• W2018302586 doi "https://doi.org/10.1016/j.ymeth.2008.05.005" @default.
• W2018302586 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2605511" @default.
• W2018302586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18573345" @default.
• W2018302586 hasPublicationYear "2008" @default.
• W2018302586 type Work @default.
• W2018302586 sameAs 2018302586 @default.
• W2018302586 citedByCount "17" @default.
• W2018302586 countsByYear W20183025862012 @default.
• W2018302586 countsByYear W20183025862014 @default.
• W2018302586 countsByYear W20183025862015 @default.
• W2018302586 countsByYear W20183025862016 @default.
• W2018302586 countsByYear W20183025862023 @default.
• W2018302586 crossrefType "journal-article" @default.
• W2018302586 hasAuthorship W2018302586A5009350001 @default.
• W2018302586 hasAuthorship W2018302586A5017857303 @default.
• W2018302586 hasAuthorship W2018302586A5042586488 @default.
• W2018302586 hasAuthorship W2018302586A5063558357 @default.
• W2018302586 hasBestOaLocation W20183025862 @default.
• W2018302586 hasConcept C126322002 @default.
• W2018302586 hasConcept C142724271 @default.
• W2018302586 hasConcept C147483822 @default.
• W2018302586 hasConcept C203014093 @default.
• W2018302586 hasConcept C2779134260 @default.
• W2018302586 hasConcept C2781197716 @default.
• W2018302586 hasConcept C504460877 @default.
• W2018302586 hasConcept C55493867 @default.
• W2018302586 hasConcept C70721500 @default.
• W2018302586 hasConcept C71924100 @default.
• W2018302586 hasConcept C86803240 @default.
• W2018302586 hasConceptScore W2018302586C126322002 @default.
• W2018302586 hasConceptScore W2018302586C142724271 @default.
• W2018302586 hasConceptScore W2018302586C147483822 @default.
• W2018302586 hasConceptScore W2018302586C203014093 @default.
• W2018302586 hasConceptScore W2018302586C2779134260 @default.
• W2018302586 hasConceptScore W2018302586C2781197716 @default.
• W2018302586 hasConceptScore W2018302586C504460877 @default.

• next