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- W2018322020 endingPage "18043" @default.
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- W2018322020 abstract "This article reports the design, synthesis, and evaluation of a novel class of molecules of intermediate size (approximately 7000 Da), which possess both the targeting and effector functions of antibodies. These compounds—called synthetic antibody mimics targeting prostate cancer (SyAM-Ps)—bind simultaneously to prostate-specific membrane antigen and Fc gamma receptor I, thus eliciting highly selective cancer cell phagocytosis. SyAMs have the potential to combine the advantages of both small-molecule and biologic therapies, and may address many drawbacks associated with available treatments for cancer and other diseases." @default.
- W2018322020 created "2016-06-24" @default.
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- W2018322020 date "2014-12-16" @default.
- W2018322020 modified "2023-10-12" @default.
- W2018322020 title "Chemically Synthesized Molecules with the Targeting and Effector Functions of Antibodies" @default.
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- W2018322020 doi "https://doi.org/10.1021/ja509513c" @default.
- W2018322020 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4291750" @default.
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