Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018332302> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2018332302 endingPage "849" @default.
- W2018332302 startingPage "844" @default.
- W2018332302 abstract "A human helper T cell line (F14m) activated by the matrix protein purified from A/X31 influenza virus has been developed. After activation by antigen for 7 days, and reculture with matrix protein and irradiated autologous feeder cells, the cells obtained from an in vivo influenza virus-immunized donor have been growing in the presence of interleukin 2 for more than 7 months. The cells all belong to the helper-inducer T cell subset and most of them express surface membrane HLA-DR antigens. A small number (approximately 103) of F14m T cells provided optimal help for 1 × 105 autologous T-depleted lymphocytes for production of anti-A/X31 but not anti-B/HK antibodies. The F14m T cells produce soluble factors (S14m) able to help B cells to secrete anti-A/×31 antibodies. F14m and S14m were shown to help antibody production to hemagglutinin when cultured with B cells and the whole virus. The specificity of the T cell line for type-A matrix protein was confirmed by the ability of S14m to provide help for anti-A/JAP (A/H2/N2) but not for anti-B/HK antibody production. These data provide evidence for matrix protein-specific T helper cells and factors able to provide help for antibody production against hemagglutinin, a distinct protein of the same virus." @default.
- W2018332302 created "2016-06-24" @default.
- W2018332302 creator A5005866571 @default.
- W2018332302 creator A5015751976 @default.
- W2018332302 creator A5029004287 @default.
- W2018332302 creator A5057580992 @default.
- W2018332302 date "1982-01-01" @default.
- W2018332302 modified "2023-09-27" @default.
- W2018332302 title "An influenza virus matrix protein-specific human T cell line with helper activity forin vitro anti-hemagglutinin antibody production" @default.
- W2018332302 cites W1484271057 @default.
- W2018332302 cites W1811768630 @default.
- W2018332302 cites W1973103992 @default.
- W2018332302 cites W1974817956 @default.
- W2018332302 cites W1984836875 @default.
- W2018332302 cites W1987266434 @default.
- W2018332302 cites W1991531264 @default.
- W2018332302 cites W2030554779 @default.
- W2018332302 cites W2038029623 @default.
- W2018332302 cites W2038323008 @default.
- W2018332302 cites W2050745720 @default.
- W2018332302 cites W2056617284 @default.
- W2018332302 cites W2068803746 @default.
- W2018332302 cites W2076895579 @default.
- W2018332302 cites W2079305869 @default.
- W2018332302 cites W2084466702 @default.
- W2018332302 cites W2100101247 @default.
- W2018332302 cites W2104498491 @default.
- W2018332302 cites W2133305280 @default.
- W2018332302 cites W2167936032 @default.
- W2018332302 doi "https://doi.org/10.1002/eji.1830121009" @default.
- W2018332302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6184237" @default.
- W2018332302 hasPublicationYear "1982" @default.
- W2018332302 type Work @default.
- W2018332302 sameAs 2018332302 @default.
- W2018332302 citedByCount "19" @default.
- W2018332302 countsByYear W20183323022014 @default.
- W2018332302 crossrefType "journal-article" @default.
- W2018332302 hasAuthorship W2018332302A5005866571 @default.
- W2018332302 hasAuthorship W2018332302A5015751976 @default.
- W2018332302 hasAuthorship W2018332302A5029004287 @default.
- W2018332302 hasAuthorship W2018332302A5057580992 @default.
- W2018332302 hasConcept C147483822 @default.
- W2018332302 hasConcept C153911025 @default.
- W2018332302 hasConcept C159047783 @default.
- W2018332302 hasConcept C159654299 @default.
- W2018332302 hasConcept C203014093 @default.
- W2018332302 hasConcept C2522874641 @default.
- W2018332302 hasConcept C2776090121 @default.
- W2018332302 hasConcept C2777546802 @default.
- W2018332302 hasConcept C2778692840 @default.
- W2018332302 hasConcept C2781416681 @default.
- W2018332302 hasConcept C54355233 @default.
- W2018332302 hasConcept C68434959 @default.
- W2018332302 hasConcept C81885089 @default.
- W2018332302 hasConcept C86803240 @default.
- W2018332302 hasConcept C8891405 @default.
- W2018332302 hasConceptScore W2018332302C147483822 @default.
- W2018332302 hasConceptScore W2018332302C153911025 @default.
- W2018332302 hasConceptScore W2018332302C159047783 @default.
- W2018332302 hasConceptScore W2018332302C159654299 @default.
- W2018332302 hasConceptScore W2018332302C203014093 @default.
- W2018332302 hasConceptScore W2018332302C2522874641 @default.
- W2018332302 hasConceptScore W2018332302C2776090121 @default.
- W2018332302 hasConceptScore W2018332302C2777546802 @default.
- W2018332302 hasConceptScore W2018332302C2778692840 @default.
- W2018332302 hasConceptScore W2018332302C2781416681 @default.
- W2018332302 hasConceptScore W2018332302C54355233 @default.
- W2018332302 hasConceptScore W2018332302C68434959 @default.
- W2018332302 hasConceptScore W2018332302C81885089 @default.
- W2018332302 hasConceptScore W2018332302C86803240 @default.
- W2018332302 hasConceptScore W2018332302C8891405 @default.
- W2018332302 hasIssue "10" @default.
- W2018332302 hasLocation W20183323021 @default.
- W2018332302 hasLocation W20183323022 @default.
- W2018332302 hasOpenAccess W2018332302 @default.
- W2018332302 hasPrimaryLocation W20183323021 @default.
- W2018332302 hasRelatedWork W2029808517 @default.
- W2018332302 hasRelatedWork W2077195343 @default.
- W2018332302 hasRelatedWork W2107100610 @default.
- W2018332302 hasRelatedWork W2119177466 @default.
- W2018332302 hasRelatedWork W2133495637 @default.
- W2018332302 hasRelatedWork W2134766479 @default.
- W2018332302 hasRelatedWork W2140188877 @default.
- W2018332302 hasRelatedWork W2163394168 @default.
- W2018332302 hasRelatedWork W2204875792 @default.
- W2018332302 hasRelatedWork W4248770357 @default.
- W2018332302 hasVolume "12" @default.
- W2018332302 isParatext "false" @default.
- W2018332302 isRetracted "false" @default.
- W2018332302 magId "2018332302" @default.
- W2018332302 workType "article" @default.