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• W2018338507 abstract "Case Reports1 November 1959LOCALIZED PRETIBIAL MYXEDEMA: REPORT OF TWO CASES TREATED WITH HYDROCORTISONE BY LOCAL INJECTIONRICHARD W. DYKE, M.D., F.A.C.P., CLAYTON E. WOOD, M.D., SOPHOCLES D. MARTY, M.D.RICHARD W. DYKE, M.D., F.A.C.P.Search for more papers by this author, CLAYTON E. WOOD, M.D.Search for more papers by this author, SOPHOCLES D. MARTY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-5-1097 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptReports of successful means of treatment for localized pretibial myxedema are of interest because of its close relationship with progressive exophthalmos, and the possibility that the same agent might likewise reduce progressive exophthalmos. Evaluation of therapy for both conditions must be done with care because of the spontaneous improvement which may occur with both, and because chronic existence of both may be associated with permanent changes from fibrosis.9, 34, 36First described in the English literature by Watson-Williams in 1895, localized pretibial myxedema has since been discussed frequently by dermatologists and, more recently, by others.1-18Research concerning the pathology and...Bibliography1. CurtisCawleyJohnwick ACEPEB: Association of progressive (malignant) exophthalmos and localized myxedema, Arch. Dermat. and Syph. 60: 318, 1949. CrossrefGoogle Scholar2. VilanovaCanadell XJM: Myxedema circumscriptum thyrotoxicum: report of two cases and remarks on its pathogenesis and treatment, J. Clin. Endocrinol. 9: 883, 1949. CrossrefGoogle Scholar3. Zugerman I: Circumscribed pretibial myxedema, New England J. Med. 251: 973, 1954. CrossrefMedlineGoogle Scholar4. 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DevittPirozynskiSamuels JEWJPB: Mast cell resistance to hormonal influence, Proc. Soc. Exper. Biol. and Med. 83: 335, 1953. CrossrefMedlineGoogle Scholar45. Aterman K: Exophthalmos: its relation to adrenocortical function, Acta endocrinol. Supp. 10: 5, 1954. CrossrefGoogle Scholar46. : Cortisone in exophthalmos: report of therapeutic trial of cortisone and corticotrophin (ACTH) in exophthalmos and exophthalmic ophthalmoplegia by a panel appointed by the Medical Research Council, Lancet 1: 6 (Jan. 1) 1955. Google Scholar47. KinsellPartridgeForeman LWJWN: The use of ACTH and cortisone in the treatment and in the differential diagnosis of malignant exophthalmos: a preliminary report, Ann. Int. Med. 38: 913, 1953. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RICHARD W. DYKE, M.D., F.A.C.P.; CLAYTON E. WOOD, M.D.; SOPHOCLES D. MARTY, M.D.Affiliations: Indianapolis, Indiana*Received for publication July 12, 1958.Presented in part at the Midwest Regional Meeting of The American College of Physicians, Urbana-Champaign, Illinois, October 12, 1957.From the Departments of Medicine of Indianapolis General Hospital and Indiana University School of Medicine, and the Department of Dermatology, Indianapolis General Hospital.Requests for reprints should be addressed to Richard W. Dyke, M.D., Indianapolis General Hospital, Indianapolis 7, Indiana. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCorticoid Therapy for Pretibial Myxedema Observations on the Long-acting Thyroid StimulatorFREDERICK L. BENOIT, FRANCIS S. GREENSPAN, M.D., F.A.C.P.LiteraturRelentless localized myxedema, with exophthalmos, clubbing of the fingers and hypertrophic osteoarthropathyLokalisiertes Myxödem bei HypothyreoseAdrenal steroid therapy of severe infiltrative ophthalmopathy of Graves' disease 1 November 1959Volume 51, Issue 5Page: 1097-1103KeywordsAttentionDermatologyFibrosisHospital medicinePathogenesisThyroid ePublished: 1 December 2008 Issue Published: 1 November 1959 PDF downloadLoading ..." @default.
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