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- W2018340382 abstract "The lactose fermentation (Lac + ) and antibiotic resistance (R + ) phenotypes were conjugally transferred from Klebsiella pneumoniae strains (K166, K182, K186, K218, and K220) to Salmonella typhi, S. typhimurium, Shigella flexneri , and Vibrio cholerae . The genes for lactose fermentation and antibiotic resistance were located on the plasmids. Further analysis of plasmid DNA from these isolates indicated the presence of multiple plasmids ( M r ranged <2.7 to 70 × 10 6 ). The Lac + R + plasmids p166 and p182 were members of the FII incompatibility group. The fertility inhibition property of plasmids, p182, p218, and p220 was fi + type. Furthermore, phage typing experiments showed that plasmids p166 and p218 (Lac + R + ) conferred the ability to inhibit the multiplication of bacteriophages 12 and 13 in S. typhimurium . However, the plasmids p182, p186, and p220 (Lac + R + ) could inhibit the visible lysis of all the 30 phages in S. typhimurium . This study describes the characterization of Lac + R + plasmids and the medical significance of an intergeneric transfer of lactose fermentation to non-lactose-fermenting pathogens." @default.
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- W2018340382 date "1987-01-01" @default.
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- W2018340382 title "Characterization of self-transmissible plasmids determining lactose fermentation and multiple antibiotic resistance in clinical strains of Klebsiella pneumoniae" @default.
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- W2018340382 doi "https://doi.org/10.1016/0147-619x(87)90003-5" @default.
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