FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018347662> ?p ?o ?g. }

• W2018347662 endingPage "1347" @default.
• W2018347662 startingPage "1341" @default.
• W2018347662 abstract "Bronchiolitis obliterans syndrome (BOS) is the main cause of late morbidity and mortality in lung transplantation. This study was designed to accurately determine the prevalence of this syndrome of chronic lung allograft dysfunction (which is presumed to be due to chronic rejection).A retrospective analysis was done of 212 consecutive lung transplantations performed at Barnes Hospital between July 1988 and March 1994 to characterize the prevalence and course of BOS. One hundred eighty-seven transplant recipients survived at least 3 months after transplantation, putting them at risk for BOS. Recipients free of BOS (group I) were distinguished from those with BOS (group II) based on the presence of declining spirometry (forced expiratory volume in 1 second persistently less than 80% of previous baseline) or histologic obliterative bronchiolitis in group II.There were 110 transplantations in group I (59%) and 77 in group II (41%). At follow-up, BOS was detected using the following criteria: declining forced expiratory volume in 1 second alone, 40 of 77 (52%); positive histologic results alone, 7 of 77 (9.1%); and both, 30 of 77 (38.9%). Declining spirometry was the most common initial sign of BOS onset (57 of 77, 74%). There were no differences between groups with respect to age, sex, indication for transplantation, or type of transplantation performed. The mortality rate was significantly higher with BOS (group II, 22 of 77 [28.6%] versus group I, 8 of 110 [7.3%]; p = 0.001) and was not related to either the type of transplantation performed or the indication for transplantation. Follow-up of group II (mean 35.1 months; range, 7.1 to 63.7 months) showed a delay until BOS onset (16.1 +/- 1.2 months); when BOS was fatal, death ensued within 11.5 +/- 2.4 months of its onset. Comparison of the first and last quartiles of recipients in this series (QTR1 versus QTR4, 53 patients in each) demonstrated a higher prevalence of BOS in QTR1 (24 with BOS of 43 at risk [55.8%] versus QTR4, 5 with BOS of 52 at risk [9.6%]; p < 0.001) and a worse BOS functional score in QTR1 (2.2 +/- 0.2 versus QTR4, 0.8 +/- 0.2; p = 0.007).(1) Bronchiolitis obliterans syndrome is truly a clinical syndrome, not simply a pathologic entity; (2) BOS displays considerable latency in onset and progression; (3) lung transplant recipients must therefore be followed up for a sufficient interval to determine the actual prevalence and mortality rate of BOS; and (4) the prevalence and mortality rates of BOS are higher than previously appreciated, exceeding 50% and 40%, respectively." @default.
• W2018347662 created "2016-06-24" @default.
• W2018347662 creator A5014718746 @default.
• W2018347662 creator A5048361872 @default.
• W2018347662 creator A5050429102 @default.
• W2018347662 creator A5070668450 @default.
• W2018347662 creator A5086650133 @default.
• W2018347662 date "1995-11-01" @default.
• W2018347662 modified "2023-10-17" @default.
• W2018347662 title "Prevalence and outcome of bronchiolitis obliterans syndrome after lung transplantation" @default.
• W2018347662 cites W1970073543 @default.
• W2018347662 cites W1995968244 @default.
• W2018347662 cites W1998720102 @default.
• W2018347662 cites W2004395966 @default.
• W2018347662 cites W2005804757 @default.
• W2018347662 cites W2016199534 @default.
• W2018347662 cites W2033383767 @default.
• W2018347662 cites W2036108273 @default.
• W2018347662 cites W2038091717 @default.
• W2018347662 cites W2043263636 @default.
• W2018347662 cites W2063779795 @default.
• W2018347662 cites W2076799432 @default.
• W2018347662 cites W2134173985 @default.
• W2018347662 cites W2159922048 @default.
• W2018347662 cites W2406252888 @default.
• W2018347662 cites W4302575026 @default.
• W2018347662 doi "https://doi.org/10.1016/0003-4975(95)00751-6" @default.
• W2018347662 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8526624" @default.
• W2018347662 hasPublicationYear "1995" @default.
• W2018347662 type Work @default.
• W2018347662 sameAs 2018347662 @default.
• W2018347662 citedByCount "183" @default.
• W2018347662 countsByYear W20183476622012 @default.
• W2018347662 countsByYear W20183476622013 @default.
• W2018347662 countsByYear W20183476622014 @default.
• W2018347662 countsByYear W20183476622015 @default.
• W2018347662 countsByYear W20183476622016 @default.
• W2018347662 countsByYear W20183476622017 @default.
• W2018347662 countsByYear W20183476622018 @default.
• W2018347662 countsByYear W20183476622019 @default.
• W2018347662 countsByYear W20183476622020 @default.
• W2018347662 countsByYear W20183476622021 @default.
• W2018347662 countsByYear W20183476622022 @default.
• W2018347662 countsByYear W20183476622023 @default.
• W2018347662 crossrefType "journal-article" @default.
• W2018347662 hasAuthorship W2018347662A5014718746 @default.
• W2018347662 hasAuthorship W2018347662A5048361872 @default.
• W2018347662 hasAuthorship W2018347662A5050429102 @default.
• W2018347662 hasAuthorship W2018347662A5070668450 @default.
• W2018347662 hasAuthorship W2018347662A5086650133 @default.
• W2018347662 hasBestOaLocation W20183476621 @default.
• W2018347662 hasConcept C126322002 @default.
• W2018347662 hasConcept C141071460 @default.
• W2018347662 hasConcept C167135981 @default.
• W2018347662 hasConcept C2776042228 @default.
• W2018347662 hasConcept C2776739411 @default.
• W2018347662 hasConcept C2777714996 @default.
• W2018347662 hasConcept C2778821649 @default.
• W2018347662 hasConcept C2780333948 @default.
• W2018347662 hasConcept C2781448352 @default.
• W2018347662 hasConcept C2911091166 @default.
• W2018347662 hasConcept C534529494 @default.
• W2018347662 hasConcept C71924100 @default.
• W2018347662 hasConceptScore W2018347662C126322002 @default.
• W2018347662 hasConceptScore W2018347662C141071460 @default.
• W2018347662 hasConceptScore W2018347662C167135981 @default.
• W2018347662 hasConceptScore W2018347662C2776042228 @default.
• W2018347662 hasConceptScore W2018347662C2776739411 @default.
• W2018347662 hasConceptScore W2018347662C2777714996 @default.
• W2018347662 hasConceptScore W2018347662C2778821649 @default.
• W2018347662 hasConceptScore W2018347662C2780333948 @default.
• W2018347662 hasConceptScore W2018347662C2781448352 @default.
• W2018347662 hasConceptScore W2018347662C2911091166 @default.
• W2018347662 hasConceptScore W2018347662C534529494 @default.
• W2018347662 hasConceptScore W2018347662C71924100 @default.
• W2018347662 hasIssue "5" @default.
• W2018347662 hasLocation W20183476621 @default.
• W2018347662 hasLocation W20183476622 @default.
• W2018347662 hasOpenAccess W2018347662 @default.
• W2018347662 hasPrimaryLocation W20183476621 @default.
• W2018347662 hasRelatedWork W1561735384 @default.
• W2018347662 hasRelatedWork W1895478142 @default.
• W2018347662 hasRelatedWork W1966155747 @default.
• W2018347662 hasRelatedWork W1966396484 @default.
• W2018347662 hasRelatedWork W1977300388 @default.
• W2018347662 hasRelatedWork W2018347662 @default.
• W2018347662 hasRelatedWork W2088315796 @default.
• W2018347662 hasRelatedWork W2404853076 @default.
• W2018347662 hasRelatedWork W2407927072 @default.
• W2018347662 hasRelatedWork W4247500566 @default.
• W2018347662 hasVolume "60" @default.
• W2018347662 isParatext "false" @default.
• W2018347662 isRetracted "false" @default.
• W2018347662 magId "2018347662" @default.
• W2018347662 workType "article" @default.