FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018348524> ?p ?o ?g. }

• W2018348524 endingPage "2131" @default.
• W2018348524 startingPage "2122" @default.
• W2018348524 abstract "ABSTRACT Studies of the transmission epidemiology of antimicrobial-resistant Escherichia coli , such as strains harboring extended-spectrum beta-lactamase (ESBL) genes, frequently use selective culture of rectal surveillance swabs to identify isolates for molecular epidemiological investigation. Typically, only single colonies are evaluated, which risks underestimating species diversity and transmission events. We sequenced the genomes of 16 E. coli colonies from each of eight fecal samples ( n = 127 genomes; one failure), taken from different individuals in Cambodia, a region of high ESBL-producing E. coli prevalence. Sequence data were used to characterize both the core chromosomal diversity of E. coli isolates and their resistance/virulence gene content as a proxy measure of accessory genome diversity. The 127 E. coli genomes represented 31 distinct sequence types (STs). Seven (88%) of eight subjects carried ESBL-positive isolates, all containing bla CTX-M variants. Diversity was substantial, with a median of four STs/individual (range, 1 to 10) and wide genetic divergence at the nucleotide level within some STs. In 2/8 (25%) individuals, the same bla CTX-M variant occurred in different clones, and/or different bla CTX-M variants occurred in the same clone. Patterns of other resistance genes and common virulence factors, representing differences in the accessory genome, were also diverse within and between clones. The substantial diversity among intestinally carried ESBL-positive E. coli bacteria suggests that fecal surveillance, particularly if based on single-colony subcultures, will likely underestimate transmission events, especially in high-prevalence settings." @default.
• W2018348524 created "2016-06-24" @default.
• W2018348524 creator A5012106795 @default.
• W2018348524 creator A5017157418 @default.
• W2018348524 creator A5028335853 @default.
• W2018348524 creator A5029126318 @default.
• W2018348524 creator A5034097318 @default.
• W2018348524 creator A5034386514 @default.
• W2018348524 creator A5044933203 @default.
• W2018348524 creator A5048005458 @default.
• W2018348524 creator A5055232452 @default.
• W2018348524 creator A5069545886 @default.
• W2018348524 creator A5069696367 @default.
• W2018348524 creator A5080328175 @default.
• W2018348524 creator A5089282433 @default.
• W2018348524 date "2015-07-01" @default.
• W2018348524 modified "2023-10-10" @default.
• W2018348524 title "Extensive Within-Host Diversity in Fecally Carried Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli Isolates: Implications for Transmission Analyses" @default.
• W2018348524 cites W113427216 @default.
• W2018348524 cites W1917197814 @default.
• W2018348524 cites W1967421806 @default.
• W2018348524 cites W1968581865 @default.
• W2018348524 cites W2004727687 @default.
• W2018348524 cites W2009772825 @default.
• W2018348524 cites W2028585341 @default.
• W2018348524 cites W2034233849 @default.
• W2018348524 cites W2034677156 @default.
• W2018348524 cites W2060053506 @default.
• W2018348524 cites W2072967720 @default.
• W2018348524 cites W2090732181 @default.
• W2018348524 cites W2091452614 @default.
• W2018348524 cites W2102692498 @default.
• W2018348524 cites W2105454624 @default.
• W2018348524 cites W2106298631 @default.
• W2018348524 cites W2109011847 @default.
• W2018348524 cites W2119034615 @default.
• W2018348524 cites W2131946678 @default.
• W2018348524 cites W2137413050 @default.
• W2018348524 cites W2142402047 @default.
• W2018348524 cites W2149753281 @default.
• W2018348524 cites W2151450070 @default.
• W2018348524 cites W2155936540 @default.
• W2018348524 cites W2158990411 @default.
• W2018348524 cites W2160501654 @default.
• W2018348524 cites W2160969485 @default.
• W2018348524 cites W2161060487 @default.
• W2018348524 cites W2162636530 @default.
• W2018348524 cites W2164757282 @default.
• W2018348524 cites W2164852757 @default.
• W2018348524 doi "https://doi.org/10.1128/jcm.00378-15" @default.
• W2018348524 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4473215" @default.
• W2018348524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25903575" @default.
• W2018348524 hasPublicationYear "2015" @default.
• W2018348524 type Work @default.
• W2018348524 sameAs 2018348524 @default.
• W2018348524 citedByCount "74" @default.
• W2018348524 countsByYear W20183485242015 @default.
• W2018348524 countsByYear W20183485242016 @default.
• W2018348524 countsByYear W20183485242017 @default.
• W2018348524 countsByYear W20183485242018 @default.
• W2018348524 countsByYear W20183485242019 @default.
• W2018348524 countsByYear W20183485242020 @default.
• W2018348524 countsByYear W20183485242021 @default.
• W2018348524 countsByYear W20183485242022 @default.
• W2018348524 countsByYear W20183485242023 @default.
• W2018348524 crossrefType "journal-article" @default.
• W2018348524 hasAuthorship W2018348524A5012106795 @default.
• W2018348524 hasAuthorship W2018348524A5017157418 @default.
• W2018348524 hasAuthorship W2018348524A5028335853 @default.
• W2018348524 hasAuthorship W2018348524A5029126318 @default.
• W2018348524 hasAuthorship W2018348524A5034097318 @default.
• W2018348524 hasAuthorship W2018348524A5034386514 @default.
• W2018348524 hasAuthorship W2018348524A5044933203 @default.
• W2018348524 hasAuthorship W2018348524A5048005458 @default.
• W2018348524 hasAuthorship W2018348524A5055232452 @default.
• W2018348524 hasAuthorship W2018348524A5069545886 @default.
• W2018348524 hasAuthorship W2018348524A5069696367 @default.
• W2018348524 hasAuthorship W2018348524A5080328175 @default.
• W2018348524 hasAuthorship W2018348524A5089282433 @default.
• W2018348524 hasBestOaLocation W20183485241 @default.
• W2018348524 hasConcept C104317684 @default.
• W2018348524 hasConcept C119599485 @default.
• W2018348524 hasConcept C127413603 @default.
• W2018348524 hasConcept C135763542 @default.
• W2018348524 hasConcept C141231307 @default.
• W2018348524 hasConcept C144024400 @default.
• W2018348524 hasConcept C149923435 @default.
• W2018348524 hasConcept C24432333 @default.
• W2018348524 hasConcept C2781288988 @default.
• W2018348524 hasConcept C2908647359 @default.
• W2018348524 hasConcept C523546767 @default.
• W2018348524 hasConcept C54355233 @default.
• W2018348524 hasConcept C547475151 @default.
• W2018348524 hasConcept C60987743 @default.
• W2018348524 hasConcept C62130838 @default.
• W2018348524 hasConcept C761482 @default.
• W2018348524 hasConcept C81977670 @default.
• W2018348524 hasConcept C86803240 @default.

• next