Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018359500> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2018359500 endingPage "34" @default.
- W2018359500 startingPage "26" @default.
- W2018359500 abstract "Direct measurement of neuropeptides in the hypothalamus is essential for neuroendocrine studies. However, the small quantities of peptides released at their neuroterminals and relatively large molecular sizes make these measurements difficult. We have evaluated microdialysis probes with two membrane materials (polycarbonate and polyarylethersulfone, both: molecular cut off 20,000 Da) in vitro, and adapted the method for in vivo hypothalamic sample collection in non-human primates. The results of in vitro experiments showed that the polyarylethersulfone membrane yielded a several fold higher recovery rate than the polycarbonate membrane. In in vivo experiments, a guide cannula with stylet was inserted into the medial basal hypothalamus through the permanently implanted cranial pedestal under light sedation. The stylet was replaced by a microdialysis probe and artificial CSF was infused. The results indicated that the neuropeptide luteinizing hormone-releasing hormone was readily measurable in dialysates collected at 10 min-intervals, and responded to neuroactive substances applied through the probe. The animals were fully conscious except for the initial hour of sampling. After the experiment the animal was returned to the home cage, and later similarly examined during several additional experiments. Therefore, the microdialysis method described here is a highly useful tool for neuroendocrine studies in non-human primates." @default.
- W2018359500 created "2016-06-24" @default.
- W2018359500 creator A5014769599 @default.
- W2018359500 creator A5061445584 @default.
- W2018359500 creator A5066397340 @default.
- W2018359500 creator A5088499837 @default.
- W2018359500 date "2008-02-01" @default.
- W2018359500 modified "2023-09-23" @default.
- W2018359500 title "Microdialysis methods for in vivo neuropeptide measurement in the Stalk-median eminence in the Rhesus monkey" @default.
- W2018359500 cites W1588182583 @default.
- W2018359500 cites W1629342912 @default.
- W2018359500 cites W1888424353 @default.
- W2018359500 cites W2005782659 @default.
- W2018359500 cites W2018378087 @default.
- W2018359500 cites W2019501332 @default.
- W2018359500 cites W2039873595 @default.
- W2018359500 cites W2066104572 @default.
- W2018359500 cites W2071775529 @default.
- W2018359500 cites W2076918107 @default.
- W2018359500 cites W2082333255 @default.
- W2018359500 cites W2083342669 @default.
- W2018359500 cites W2091672803 @default.
- W2018359500 cites W2093606839 @default.
- W2018359500 cites W2101157967 @default.
- W2018359500 cites W2103637408 @default.
- W2018359500 cites W2126836250 @default.
- W2018359500 cites W2143545787 @default.
- W2018359500 doi "https://doi.org/10.1016/j.jneumeth.2007.09.001" @default.
- W2018359500 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2386413" @default.
- W2018359500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17936911" @default.
- W2018359500 hasPublicationYear "2008" @default.
- W2018359500 type Work @default.
- W2018359500 sameAs 2018359500 @default.
- W2018359500 citedByCount "24" @default.
- W2018359500 countsByYear W20183595002012 @default.
- W2018359500 countsByYear W20183595002013 @default.
- W2018359500 countsByYear W20183595002015 @default.
- W2018359500 countsByYear W20183595002016 @default.
- W2018359500 countsByYear W20183595002017 @default.
- W2018359500 countsByYear W20183595002018 @default.
- W2018359500 countsByYear W20183595002019 @default.
- W2018359500 countsByYear W20183595002022 @default.
- W2018359500 countsByYear W20183595002023 @default.
- W2018359500 crossrefType "journal-article" @default.
- W2018359500 hasAuthorship W2018359500A5014769599 @default.
- W2018359500 hasAuthorship W2018359500A5061445584 @default.
- W2018359500 hasAuthorship W2018359500A5066397340 @default.
- W2018359500 hasAuthorship W2018359500A5088499837 @default.
- W2018359500 hasBestOaLocation W20183595002 @default.
- W2018359500 hasConcept C118303440 @default.
- W2018359500 hasConcept C141071460 @default.
- W2018359500 hasConcept C150903083 @default.
- W2018359500 hasConcept C170493617 @default.
- W2018359500 hasConcept C185592680 @default.
- W2018359500 hasConcept C207001950 @default.
- W2018359500 hasConcept C2778074680 @default.
- W2018359500 hasConcept C50156730 @default.
- W2018359500 hasConcept C55493867 @default.
- W2018359500 hasConcept C71924100 @default.
- W2018359500 hasConcept C86803240 @default.
- W2018359500 hasConceptScore W2018359500C118303440 @default.
- W2018359500 hasConceptScore W2018359500C141071460 @default.
- W2018359500 hasConceptScore W2018359500C150903083 @default.
- W2018359500 hasConceptScore W2018359500C170493617 @default.
- W2018359500 hasConceptScore W2018359500C185592680 @default.
- W2018359500 hasConceptScore W2018359500C207001950 @default.
- W2018359500 hasConceptScore W2018359500C2778074680 @default.
- W2018359500 hasConceptScore W2018359500C50156730 @default.
- W2018359500 hasConceptScore W2018359500C55493867 @default.
- W2018359500 hasConceptScore W2018359500C71924100 @default.
- W2018359500 hasConceptScore W2018359500C86803240 @default.
- W2018359500 hasIssue "1" @default.
- W2018359500 hasLocation W20183595001 @default.
- W2018359500 hasLocation W20183595002 @default.
- W2018359500 hasLocation W20183595003 @default.
- W2018359500 hasLocation W20183595004 @default.
- W2018359500 hasOpenAccess W2018359500 @default.
- W2018359500 hasPrimaryLocation W20183595001 @default.
- W2018359500 hasRelatedWork W1969002119 @default.
- W2018359500 hasRelatedWork W1972861168 @default.
- W2018359500 hasRelatedWork W2034057476 @default.
- W2018359500 hasRelatedWork W2051207867 @default.
- W2018359500 hasRelatedWork W2071775529 @default.
- W2018359500 hasRelatedWork W2129285568 @default.
- W2018359500 hasRelatedWork W2369156150 @default.
- W2018359500 hasRelatedWork W2378945660 @default.
- W2018359500 hasRelatedWork W2385749386 @default.
- W2018359500 hasRelatedWork W3099662680 @default.
- W2018359500 hasVolume "168" @default.
- W2018359500 isParatext "false" @default.
- W2018359500 isRetracted "false" @default.
- W2018359500 magId "2018359500" @default.
- W2018359500 workType "article" @default.