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- W2018392605 abstract "Retinopathy of prematurity (ROP) is a vasoproliferative retinal disorder in premature infants that can lead to blindness and the incidence is increasing with increased survival of infants born at very early gestational age and low birth weight. Majority of common diseases are complex and multifactorial resulting from the interplay of genetic components and environmental factors. As no single gene or genetic variant on its own can cause the disease pathology, complexities associated with common diseases present unique challenges for management and therapy. Genome wide association and resequencing projects together with gene environment interaction studies are expected to further define the causal relationships that connect genetic variants to ROP pathogenesis and should assist in better design of prevention and intervention. This review summarizes the recent literature on ROP with a special focus to recognize the genetic basis of the disease." @default.
- W2018392605 created "2016-06-24" @default.
- W2018392605 creator A5010504178 @default.
- W2018392605 date "2014-09-01" @default.
- W2018392605 modified "2023-09-26" @default.
- W2018392605 title "Genetic Susceptibility to Retinopathy of Prematurity: A Paradigm for Preterm Disease Traits" @default.
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- W2018392605 doi "https://doi.org/10.7869/djo.73" @default.
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