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- W2018395911 abstract "Objectives: To compare and quantify the presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aac) and Porphyromonas gingivalis (Pg) in Down's syndrome (DS) and systemically healthy subjects with periodontitis and gingivitis. Materials and Methods: Fifty‑nine age‑matched subjectswere categorized into four groups; Group I: DS subjects with gingivitis, Group II: DS subjects with periodontitis, Group III: Systemically healthy subjects with gingivitis and Group IV: Systemically healthy subjects with periodontitis.Plaque samples from all the four groups were collected and analyzed to evaluate the presence of Aac and Pg using real time polymerase chain reaction. The indices used were oral hygiene index simplified, community periodontalindex for treatment needs and plaque index. Results: This study showed a statistically significant detection inthe levels of both Aac (<0.001) and Pg (<0.001) in DS subjects with periodontitis when compared with the healthycontrols with periodontitis; moreover, there was a statistically significant increase in Pg levels compared to Aac inDS gingivitis group. Conclusion: There was a statistically significant presence of Pg and Aac in both DS gingivitisand DS periodontitis over control groups with increased levels of Pg compared with Aac in DS gingivitis group." @default.
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- W2018395911 date "2014-01-01" @default.
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- W2018395911 title "Assessment of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in Down′s syndrome subjects and systemically healthy subjects: A comparative clinical trial" @default.
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- W2018395911 doi "https://doi.org/10.4103/0972-124x.147408" @default.
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