FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018400501> ?p ?o ?g. }

• W2018400501 endingPage "141" @default.
• W2018400501 startingPage "134" @default.
• W2018400501 abstract "The neuraminidase of influenza viruses is the target of the inhibitors oseltamivir and zanamivir. Recent reports on influenza viruses with reduced susceptibility to neuraminidase inhibitors (NAI) are a cause for concern. Several amino acid substitutions, each as a consequence of one single nucleotide mutation, are known to confer resistance to NAI. An increase of NAI-resistant viruses appears to be likely as a result of a wider application of NAI for treatment and prophylaxis of seasonal influenza infections. Monitoring the occurrence and spread of resistant viruses is an important task. Therefore, RT-PCR assays were developed with subsequent pyrosequencing analysis (PSQ-PCR). These assays allow a rapid, high-throughput and cost-effective screening of subtype A/H1N1, A/H3N2, and A/H5N1 viruses. Various specimens such as respiratory swabs, allantoic fluid, or cell-propagated viruses can be used and results are available within hours. Several A/H1N1, A/H3N2, and A/H5N1 viruses isolated from human and avian specimens were tested to evaluate the method. Positive controls encoding resistance-associated mutations were created using site-directed mutagenesis. The results obtained with these controls showed that the assay can discriminate clearly the wild-type virus from a mutant virus. The detection limit of minor virus variants within the viral quasispecies amounts to 10%." @default.
• W2018400501 created "2016-06-24" @default.
• W2018400501 creator A5029808844 @default.
• W2018400501 creator A5042686464 @default.
• W2018400501 date "2008-11-01" @default.
• W2018400501 modified "2023-10-16" @default.
• W2018400501 title "A new and rapid genotypic assay for the detection of neuraminidase inhibitor resistant influenza A viruses of subtype H1N1, H3N2, and H5N1" @default.
• W2018400501 cites W1994057432 @default.
• W2018400501 cites W1994644330 @default.
• W2018400501 cites W2001734810 @default.
• W2018400501 cites W2032308407 @default.
• W2018400501 cites W2042995083 @default.
• W2018400501 cites W2046745698 @default.
• W2018400501 cites W2075704126 @default.
• W2018400501 cites W2086035737 @default.
• W2018400501 cites W2103337073 @default.
• W2018400501 cites W2104397822 @default.
• W2018400501 cites W2104814883 @default.
• W2018400501 cites W2107176682 @default.
• W2018400501 cites W2110421864 @default.
• W2018400501 cites W2111155300 @default.
• W2018400501 cites W2112318650 @default.
• W2018400501 cites W2117004115 @default.
• W2018400501 cites W2126078732 @default.
• W2018400501 cites W2130441728 @default.
• W2018400501 cites W2138198678 @default.
• W2018400501 cites W2147247273 @default.
• W2018400501 cites W2148249666 @default.
• W2018400501 cites W2149087734 @default.
• W2018400501 cites W2153232301 @default.
• W2018400501 cites W2155447554 @default.
• W2018400501 cites W2157177671 @default.
• W2018400501 cites W2159812729 @default.
• W2018400501 cites W2164368077 @default.
• W2018400501 cites W2165202620 @default.
• W2018400501 cites W41880533 @default.
• W2018400501 doi "https://doi.org/10.1016/j.jviromet.2008.07.017" @default.
• W2018400501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18725246" @default.
• W2018400501 hasPublicationYear "2008" @default.
• W2018400501 type Work @default.
• W2018400501 sameAs 2018400501 @default.
• W2018400501 citedByCount "47" @default.
• W2018400501 countsByYear W20184005012012 @default.
• W2018400501 countsByYear W20184005012013 @default.
• W2018400501 countsByYear W20184005012014 @default.
• W2018400501 countsByYear W20184005012015 @default.
• W2018400501 countsByYear W20184005012016 @default.
• W2018400501 countsByYear W20184005012017 @default.
• W2018400501 countsByYear W20184005012022 @default.
• W2018400501 countsByYear W20184005012023 @default.
• W2018400501 crossrefType "journal-article" @default.
• W2018400501 hasAuthorship W2018400501A5029808844 @default.
• W2018400501 hasAuthorship W2018400501A5042686464 @default.
• W2018400501 hasConcept C104317684 @default.
• W2018400501 hasConcept C134164806 @default.
• W2018400501 hasConcept C135763542 @default.
• W2018400501 hasConcept C142724271 @default.
• W2018400501 hasConcept C14500911 @default.
• W2018400501 hasConcept C156719811 @default.
• W2018400501 hasConcept C159047783 @default.
• W2018400501 hasConcept C182707283 @default.
• W2018400501 hasConcept C2522874641 @default.
• W2018400501 hasConcept C2776408679 @default.
• W2018400501 hasConcept C2777538117 @default.
• W2018400501 hasConcept C2777546802 @default.
• W2018400501 hasConcept C2778692840 @default.
• W2018400501 hasConcept C2779134260 @default.
• W2018400501 hasConcept C2780374985 @default.
• W2018400501 hasConcept C2781416681 @default.
• W2018400501 hasConcept C2781442963 @default.
• W2018400501 hasConcept C3008058167 @default.
• W2018400501 hasConcept C49105822 @default.
• W2018400501 hasConcept C519248777 @default.
• W2018400501 hasConcept C524204448 @default.
• W2018400501 hasConcept C54355233 @default.
• W2018400501 hasConcept C71924100 @default.
• W2018400501 hasConcept C82988372 @default.
• W2018400501 hasConcept C86803240 @default.
• W2018400501 hasConcept C89423630 @default.
• W2018400501 hasConceptScore W2018400501C104317684 @default.
• W2018400501 hasConceptScore W2018400501C134164806 @default.
• W2018400501 hasConceptScore W2018400501C135763542 @default.
• W2018400501 hasConceptScore W2018400501C142724271 @default.
• W2018400501 hasConceptScore W2018400501C14500911 @default.
• W2018400501 hasConceptScore W2018400501C156719811 @default.
• W2018400501 hasConceptScore W2018400501C159047783 @default.
• W2018400501 hasConceptScore W2018400501C182707283 @default.
• W2018400501 hasConceptScore W2018400501C2522874641 @default.
• W2018400501 hasConceptScore W2018400501C2776408679 @default.
• W2018400501 hasConceptScore W2018400501C2777538117 @default.
• W2018400501 hasConceptScore W2018400501C2777546802 @default.
• W2018400501 hasConceptScore W2018400501C2778692840 @default.
• W2018400501 hasConceptScore W2018400501C2779134260 @default.
• W2018400501 hasConceptScore W2018400501C2780374985 @default.
• W2018400501 hasConceptScore W2018400501C2781416681 @default.
• W2018400501 hasConceptScore W2018400501C2781442963 @default.
• W2018400501 hasConceptScore W2018400501C3008058167 @default.
• W2018400501 hasConceptScore W2018400501C49105822 @default.

• next