FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018432471> ?p ?o ?g. }

• W2018432471 endingPage "4717" @default.
• W2018432471 startingPage "4705" @default.
• W2018432471 abstract "The aim of this study is to investigate the gene–environment interactions between the G48A polymorphism in the alcohol dehydrogenase-2 (ADH2) gene and environmental factors in determining the risk of esophageal cancer (EC). A literature search was conducted in the PubMed, Embase, Web of Science, Cochrane Library, and Google Scholar databases to indentify eligible studies published before November 1, 2013. We performed a meta-analysis of 18 case–control studies with a total of 8,906 EC patients and 13,712 controls. The overall analysis suggested that individuals with the GG genotype were associated with a 2.77-fold increased risk of EC, compared with carriers of the GA and AA genotypes. In a stratified analysis by ethnic group, Japanese, Mainland Chinese, and Taiwan Chinese with the GG genotype had a significantly higher risk of EC, compared with Thai and Iranian populations, indicating ethnic variance in EC susceptibility. An analysis of combined effect indicated that GG genotype of ADH2 G48A was associated with the highest risk of EC in heavy drinkers and smokers. A striking difference was found to exist between males and females, showing gender variance for the association between ADH2 G48A and EC risk. This meta-analysis shows that the GG genotype of ADH2 G48A may be associated with an increased risk of EC in Asian populations. In addition, significant gene–environment interactions were found. Heavy drinkers, smokers, and males with the GG genotype may have a higher EC risk. Thus, our results shed new light on the complex gene–environment interactions that exist between environmental factors and ADH2 G48A polymorphism in EC risk." @default.
• W2018432471 created "2016-06-24" @default.
• W2018432471 creator A5007396568 @default.
• W2018432471 creator A5023185995 @default.
• W2018432471 creator A5033941190 @default.
• W2018432471 creator A5047234646 @default.
• W2018432471 creator A5053204257 @default.
• W2018432471 creator A5054651477 @default.
• W2018432471 creator A5059556029 @default.
• W2018432471 creator A5069448029 @default.
• W2018432471 creator A5069590387 @default.
• W2018432471 date "2014-01-21" @default.
• W2018432471 modified "2023-10-17" @default.
• W2018432471 title "Gene–environment interactions on the risk of esophageal cancer among Asian populations with the G48A polymorphism in the alcohol dehydrogenase-2 gene: a meta-analysis" @default.
• W2018432471 cites W1529058556 @default.
• W2018432471 cites W1551600243 @default.
• W2018432471 cites W1593002469 @default.
• W2018432471 cites W1979757186 @default.
• W2018432471 cites W1987466914 @default.
• W2018432471 cites W1992220669 @default.
• W2018432471 cites W1992837744 @default.
• W2018432471 cites W1995249037 @default.
• W2018432471 cites W1995560522 @default.
• W2018432471 cites W1997828131 @default.
• W2018432471 cites W2002733346 @default.
• W2018432471 cites W2006612367 @default.
• W2018432471 cites W2007801750 @default.
• W2018432471 cites W2009827958 @default.
• W2018432471 cites W2015452353 @default.
• W2018432471 cites W2015764936 @default.
• W2018432471 cites W2025753332 @default.
• W2018432471 cites W2030048339 @default.
• W2018432471 cites W2033299471 @default.
• W2018432471 cites W2057846398 @default.
• W2018432471 cites W2062009962 @default.
• W2018432471 cites W2075079870 @default.
• W2018432471 cites W2082377575 @default.
• W2018432471 cites W2091851010 @default.
• W2018432471 cites W2100770142 @default.
• W2018432471 cites W2102141030 @default.
• W2018432471 cites W2106787323 @default.
• W2018432471 cites W2110283622 @default.
• W2018432471 cites W2111674123 @default.
• W2018432471 cites W2114615906 @default.
• W2018432471 cites W2114715773 @default.
• W2018432471 cites W2116475791 @default.
• W2018432471 cites W2121110695 @default.
• W2018432471 cites W2125386601 @default.
• W2018432471 cites W2126930838 @default.
• W2018432471 cites W2126945850 @default.
• W2018432471 cites W2131602863 @default.
• W2018432471 cites W2133467689 @default.
• W2018432471 cites W2134852288 @default.
• W2018432471 cites W2138288952 @default.
• W2018432471 cites W2153043827 @default.
• W2018432471 cites W2157823046 @default.
• W2018432471 cites W2160284047 @default.
• W2018432471 cites W2160612502 @default.
• W2018432471 cites W2163812116 @default.
• W2018432471 cites W2178697278 @default.
• W2018432471 cites W2318048476 @default.
• W2018432471 cites W4241577617 @default.
• W2018432471 doi "https://doi.org/10.1007/s13277-014-1616-7" @default.
• W2018432471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24446180" @default.
• W2018432471 hasPublicationYear "2014" @default.
• W2018432471 type Work @default.
• W2018432471 sameAs 2018432471 @default.
• W2018432471 citedByCount "16" @default.
• W2018432471 countsByYear W20184324712015 @default.
• W2018432471 countsByYear W20184324712016 @default.
• W2018432471 countsByYear W20184324712017 @default.
• W2018432471 countsByYear W20184324712018 @default.
• W2018432471 countsByYear W20184324712019 @default.
• W2018432471 countsByYear W20184324712023 @default.
• W2018432471 crossrefType "journal-article" @default.
• W2018432471 hasAuthorship W2018432471A5007396568 @default.
• W2018432471 hasAuthorship W2018432471A5023185995 @default.
• W2018432471 hasAuthorship W2018432471A5033941190 @default.
• W2018432471 hasAuthorship W2018432471A5047234646 @default.
• W2018432471 hasAuthorship W2018432471A5053204257 @default.
• W2018432471 hasAuthorship W2018432471A5054651477 @default.
• W2018432471 hasAuthorship W2018432471A5059556029 @default.
• W2018432471 hasAuthorship W2018432471A5069448029 @default.
• W2018432471 hasAuthorship W2018432471A5069590387 @default.
• W2018432471 hasConcept C104317684 @default.
• W2018432471 hasConcept C121608353 @default.
• W2018432471 hasConcept C126322002 @default.
• W2018432471 hasConcept C135763542 @default.
• W2018432471 hasConcept C143998085 @default.
• W2018432471 hasConcept C187960798 @default.
• W2018432471 hasConcept C2776478404 @default.
• W2018432471 hasConcept C2777344606 @default.
• W2018432471 hasConcept C2779742542 @default.
• W2018432471 hasConcept C2781066024 @default.
• W2018432471 hasConcept C54355233 @default.
• W2018432471 hasConcept C55493867 @default.
• W2018432471 hasConcept C71924100 @default.
• W2018432471 hasConcept C86803240 @default.

• next