FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018448511> ?p ?o ?g. }

• W2018448511 endingPage "122" @default.
• W2018448511 startingPage "113" @default.
• W2018448511 abstract "The present study uses an unique capillary electrophoresis (CE) approach, that we have termed ion-interaction capillary zone electrophoresis (II-CZE), for the separation of diastereomeric peptide pairs where a single site in the centre of the non-polar face of an 18-residue amphipathic alpha-helical peptide is substituted by the 19 L- or D-amino acids. Through the addition of perfluorinated acids at very high concentrations (up to 400 mM), such concentration levels not having been used previously in chromatography or CE, to the background electrolyte (pH 2.0), we have been able to achieve baseline resolution of all 19 diastereomeric peptide pairs with an uncoated capillary. Since each diastereomeric peptide pair has the same sequence, identical mass-to-charge ratio and identical intrinsic hydrophobicity, such a separation by CZE has previously been considered theoretically impossible. Excellent resolution was achieved due to maximum advantage being taken of even subtle disruption of peptide structure/conformation (due to the presence of D-amino acids) of the non-polar face of the amphipathic alpha-helix and its interaction with the hydrophobic anionic ion-pairing reagents. In addition, due to the excellent resolution of diastereomeric peptide pairs by this novel CZE approach, we have also been able to separate a mixture of these closely-related alpha-helical peptides." @default.
• W2018448511 created "2016-06-24" @default.
• W2018448511 creator A5034503474 @default.
• W2018448511 creator A5052295449 @default.
• W2018448511 creator A5086685010 @default.
• W2018448511 creator A5090133744 @default.
• W2018448511 date "2004-07-01" @default.
• W2018448511 modified "2023-10-10" @default.
• W2018448511 title "Capillary zone electrophoresis of α-helical diastereomeric peptide pairs with anionic ion-pairing reagents" @default.
• W2018448511 cites W134500059 @default.
• W2018448511 cites W1479986601 @default.
• W2018448511 cites W1982258330 @default.
• W2018448511 cites W1985363330 @default.
• W2018448511 cites W1986049988 @default.
• W2018448511 cites W2001350069 @default.
• W2018448511 cites W2004742488 @default.
• W2018448511 cites W2012953087 @default.
• W2018448511 cites W2024331436 @default.
• W2018448511 cites W2044294967 @default.
• W2018448511 cites W2048075789 @default.
• W2018448511 cites W2048790256 @default.
• W2018448511 cites W2055906852 @default.
• W2018448511 cites W2055970915 @default.
• W2018448511 cites W2056123667 @default.
• W2018448511 cites W2056914458 @default.
• W2018448511 cites W2070585675 @default.
• W2018448511 cites W2076070840 @default.
• W2018448511 cites W2080941120 @default.
• W2018448511 cites W2082861817 @default.
• W2018448511 cites W2084082061 @default.
• W2018448511 cites W2091115495 @default.
• W2018448511 cites W2092259583 @default.
• W2018448511 cites W2126521510 @default.
• W2018448511 cites W4230015884 @default.
• W2018448511 cites W4302200385 @default.
• W2018448511 cites W43730763 @default.
• W2018448511 doi "https://doi.org/10.1016/j.chroma.2004.04.029" @default.
• W2018448511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15317419" @default.
• W2018448511 hasPublicationYear "2004" @default.
• W2018448511 type Work @default.
• W2018448511 sameAs 2018448511 @default.
• W2018448511 citedByCount "17" @default.
• W2018448511 countsByYear W20184485112014 @default.
• W2018448511 crossrefType "journal-article" @default.
• W2018448511 hasAuthorship W2018448511A5034503474 @default.
• W2018448511 hasAuthorship W2018448511A5052295449 @default.
• W2018448511 hasAuthorship W2018448511A5086685010 @default.
• W2018448511 hasAuthorship W2018448511A5090133744 @default.
• W2018448511 hasConcept C121332964 @default.
• W2018448511 hasConcept C124668440 @default.
• W2018448511 hasConcept C138268822 @default.
• W2018448511 hasConcept C138716334 @default.
• W2018448511 hasConcept C154945302 @default.
• W2018448511 hasConcept C178790620 @default.
• W2018448511 hasConcept C185592680 @default.
• W2018448511 hasConcept C20621625 @default.
• W2018448511 hasConcept C2779281246 @default.
• W2018448511 hasConcept C2900643 @default.
• W2018448511 hasConcept C40875361 @default.
• W2018448511 hasConcept C41008148 @default.
• W2018448511 hasConcept C43617362 @default.
• W2018448511 hasConcept C515207424 @default.
• W2018448511 hasConcept C52703039 @default.
• W2018448511 hasConcept C55493867 @default.
• W2018448511 hasConcept C62520636 @default.
• W2018448511 hasConcept C71240020 @default.
• W2018448511 hasConcept C7602139 @default.
• W2018448511 hasConcept C8010536 @default.
• W2018448511 hasConceptScore W2018448511C121332964 @default.
• W2018448511 hasConceptScore W2018448511C124668440 @default.
• W2018448511 hasConceptScore W2018448511C138268822 @default.
• W2018448511 hasConceptScore W2018448511C138716334 @default.
• W2018448511 hasConceptScore W2018448511C154945302 @default.
• W2018448511 hasConceptScore W2018448511C178790620 @default.
• W2018448511 hasConceptScore W2018448511C185592680 @default.
• W2018448511 hasConceptScore W2018448511C20621625 @default.
• W2018448511 hasConceptScore W2018448511C2779281246 @default.
• W2018448511 hasConceptScore W2018448511C2900643 @default.
• W2018448511 hasConceptScore W2018448511C40875361 @default.
• W2018448511 hasConceptScore W2018448511C41008148 @default.
• W2018448511 hasConceptScore W2018448511C43617362 @default.
• W2018448511 hasConceptScore W2018448511C515207424 @default.
• W2018448511 hasConceptScore W2018448511C52703039 @default.
• W2018448511 hasConceptScore W2018448511C55493867 @default.
• W2018448511 hasConceptScore W2018448511C62520636 @default.
• W2018448511 hasConceptScore W2018448511C71240020 @default.
• W2018448511 hasConceptScore W2018448511C7602139 @default.
• W2018448511 hasConceptScore W2018448511C8010536 @default.
• W2018448511 hasIssue "1" @default.
• W2018448511 hasLocation W20184485111 @default.
• W2018448511 hasLocation W20184485112 @default.
• W2018448511 hasOpenAccess W2018448511 @default.
• W2018448511 hasPrimaryLocation W20184485111 @default.
• W2018448511 hasRelatedWork W1492863380 @default.
• W2018448511 hasRelatedWork W2010820983 @default.
• W2018448511 hasRelatedWork W2011681185 @default.
• W2018448511 hasRelatedWork W2036559059 @default.
• W2018448511 hasRelatedWork W2056730143 @default.

• next