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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018448695> ?p ?o ?g. }

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• W2018448695 startingPage "2097" @default.
• W2018448695 abstract "The carboxyl-terminal domain of colicin E5 was shown to inhibit protein synthesis of Escherichia coli. Its target, as revealed through in vivo and in vitro experiments, was not ribosomes as in the case of E3, but the transfer RNAs (tRNAs) for Tyr, His, Asn, and Asp, which contain a modified base, queuine, at the wobble position of each anticodon. The E5 carboxyl-terminal domain hydrolyzed these tRNAs just on the 3' side of this nucleotide. Tight correlation was observed between the toxicity of E5 and the cleavage of intracellular tRNAs of this group, implying that these tRNAs are the primary targets of colicin E5." @default.
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• W2018448695 date "1999-03-26" @default.
• W2018448695 modified "2023-10-01" @default.
• W2018448695 title "A Cytotoxic Ribonuclease Targeting Specific Transfer RNA Anticodons" @default.
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• W2018448695 doi "https://doi.org/10.1126/science.283.5410.2097" @default.
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