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- W2018461502 abstract "We have studied the architecture of parallel beta-sheets in proteins and focused on the residues that initiate and terminate the beta-strands. These beta-breaker residues are at the origin of the kink between the beta-strand and the turn that precedes or follows it. beta-Breakers can be located automatically using a consensus approach based on algorithmic secondary structure assignment, solvent accessibility and backbone dihedral angles. These beta-breakers are conformationally homogeneous with respect to side-chain solvent accessibility and backbone dihedral angle profile. A sequence-structure correlation is noted: a restricted subset of amino acids is observed at these positions. Analysis of homologous protein sequences shows that these residues are more highly conserved than other residues in the loop. We conclude that beta-breakers are the structural analogs of the N and C-terminal caps of alpha-helices. The identification of this aperiodic substructure suggests a strategy for improving secondary structure prediction and may guide site-directed mutagenesis experiments." @default.
- W2018461502 created "2016-06-24" @default.
- W2018461502 creator A5047643991 @default.
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- W2018461502 date "1991-09-01" @default.
- W2018461502 modified "2023-10-15" @default.
- W2018461502 title "β-Breakers: An aperiodic secondary structure" @default.
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- W2018461502 cites W1606011614 @default.
- W2018461502 cites W1773127169 @default.
- W2018461502 cites W1875021313 @default.
- W2018461502 cites W1938076748 @default.
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- W2018461502 doi "https://doi.org/10.1016/0022-2836(91)80075-6" @default.
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