Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018474558> ?p ?o ?g. }
- W2018474558 endingPage "6390" @default.
- W2018474558 startingPage "6386" @default.
- W2018474558 abstract "A chromatin protein, A24, a conjugate of histone H2A and evolutionally conserved ubiquitin, was virtually the only structural polypeptide that was present in interphase but missing in mitosis of a Chinese hamster cell line (DON). Because a 10% increase in the H2A/DNA ratio observed in interphase-mitosis transition explained the stoichiometric conversion of A24 to H2A, it appears that ubiquitin bound to H2A of nucleosomal surfaces in interphase is released at mitosis whereas the total H2A remains as a structural component of nucleosomes. Regardless of protein synthesis, ubiquitin was again bound to H2A when cells entered the G1 phase. Based on the electrostatic nature of the COOH-terminal region of H2A, where ubiquitin binds, and the mitosis-specific rise of covalently linked phosphates in histones H1 and H3, we propose that an ionic interaction between the positively charged H2A COOH-terminal regions on fibers and negatively charged phosphates linked to serine or threonine of H1 and H3 molecules on adjacent fibers could generate an assembly of chromatin fibers in mitosis." @default.
- W2018474558 created "2016-06-24" @default.
- W2018474558 creator A5057299622 @default.
- W2018474558 creator A5087302389 @default.
- W2018474558 creator A5090688677 @default.
- W2018474558 date "1979-12-01" @default.
- W2018474558 modified "2023-09-26" @default.
- W2018474558 title "Disappearance of a structural chromatin protein A24 in mitosis: implications for molecular basis of chromatin condensation." @default.
- W2018474558 cites W1520616376 @default.
- W2018474558 cites W1555044868 @default.
- W2018474558 cites W1559385063 @default.
- W2018474558 cites W1563004320 @default.
- W2018474558 cites W1565988507 @default.
- W2018474558 cites W1570759257 @default.
- W2018474558 cites W1596325941 @default.
- W2018474558 cites W1914441096 @default.
- W2018474558 cites W1988232414 @default.
- W2018474558 cites W1995527354 @default.
- W2018474558 cites W1996555564 @default.
- W2018474558 cites W2001274114 @default.
- W2018474558 cites W2002223314 @default.
- W2018474558 cites W2011364690 @default.
- W2018474558 cites W2018289835 @default.
- W2018474558 cites W2018626566 @default.
- W2018474558 cites W2027871922 @default.
- W2018474558 cites W2028895755 @default.
- W2018474558 cites W2029209415 @default.
- W2018474558 cites W2033299243 @default.
- W2018474558 cites W2037059281 @default.
- W2018474558 cites W2042203056 @default.
- W2018474558 cites W2044825578 @default.
- W2018474558 cites W2049268233 @default.
- W2018474558 cites W2050199365 @default.
- W2018474558 cites W2051237347 @default.
- W2018474558 cites W2054609805 @default.
- W2018474558 cites W2059722081 @default.
- W2018474558 cites W2065362756 @default.
- W2018474558 cites W2066088183 @default.
- W2018474558 cites W2069469862 @default.
- W2018474558 cites W2076562349 @default.
- W2018474558 cites W2077712685 @default.
- W2018474558 cites W2080858768 @default.
- W2018474558 cites W2087527932 @default.
- W2018474558 cites W2100837269 @default.
- W2018474558 cites W2240726600 @default.
- W2018474558 cites W2322149866 @default.
- W2018474558 cites W2324590100 @default.
- W2018474558 cites W2338600139 @default.
- W2018474558 cites W960593359 @default.
- W2018474558 cites W1679935457 @default.
- W2018474558 doi "https://doi.org/10.1073/pnas.76.12.6386" @default.
- W2018474558 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/411869" @default.
- W2018474558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/293727" @default.
- W2018474558 hasPublicationYear "1979" @default.
- W2018474558 type Work @default.
- W2018474558 sameAs 2018474558 @default.
- W2018474558 citedByCount "174" @default.
- W2018474558 countsByYear W20184745582012 @default.
- W2018474558 countsByYear W20184745582013 @default.
- W2018474558 countsByYear W20184745582015 @default.
- W2018474558 countsByYear W20184745582016 @default.
- W2018474558 countsByYear W20184745582019 @default.
- W2018474558 countsByYear W20184745582020 @default.
- W2018474558 countsByYear W20184745582021 @default.
- W2018474558 countsByYear W20184745582022 @default.
- W2018474558 crossrefType "journal-article" @default.
- W2018474558 hasAuthorship W2018474558A5057299622 @default.
- W2018474558 hasAuthorship W2018474558A5087302389 @default.
- W2018474558 hasAuthorship W2018474558A5090688677 @default.
- W2018474558 hasBestOaLocation W20184745581 @default.
- W2018474558 hasConcept C104317684 @default.
- W2018474558 hasConcept C12554922 @default.
- W2018474558 hasConcept C148196450 @default.
- W2018474558 hasConcept C178108356 @default.
- W2018474558 hasConcept C185592680 @default.
- W2018474558 hasConcept C29452124 @default.
- W2018474558 hasConcept C45413362 @default.
- W2018474558 hasConcept C552990157 @default.
- W2018474558 hasConcept C55493867 @default.
- W2018474558 hasConcept C64927066 @default.
- W2018474558 hasConcept C83640560 @default.
- W2018474558 hasConcept C84772758 @default.
- W2018474558 hasConcept C86803240 @default.
- W2018474558 hasConcept C93304396 @default.
- W2018474558 hasConcept C95444343 @default.
- W2018474558 hasConceptScore W2018474558C104317684 @default.
- W2018474558 hasConceptScore W2018474558C12554922 @default.
- W2018474558 hasConceptScore W2018474558C148196450 @default.
- W2018474558 hasConceptScore W2018474558C178108356 @default.
- W2018474558 hasConceptScore W2018474558C185592680 @default.
- W2018474558 hasConceptScore W2018474558C29452124 @default.
- W2018474558 hasConceptScore W2018474558C45413362 @default.
- W2018474558 hasConceptScore W2018474558C552990157 @default.
- W2018474558 hasConceptScore W2018474558C55493867 @default.
- W2018474558 hasConceptScore W2018474558C64927066 @default.
- W2018474558 hasConceptScore W2018474558C83640560 @default.
- W2018474558 hasConceptScore W2018474558C84772758 @default.
- W2018474558 hasConceptScore W2018474558C86803240 @default.