FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018477213> ?p ?o ?g. }

• W2018477213 endingPage "1148" @default.
• W2018477213 startingPage "1144" @default.
• W2018477213 abstract "Abstract Psoriasis is a chronic disease characterized by keratinocyte hyperproliferation and inflammation. It has been demonstrated that the expression of calcitonin gene‐related peptide (CGRP) is elevated in psoriasis lesions and CGRP‐containing neuropeptide nerve fibers are denser in the psoriatic epidermis. CGRP has been previously described to influence proliferation of several cell types, such as Schwann cell, tracheal epithelial cells, and human gingival fibroblasts. In the present study, we determined the effect of CGRP on HaCaT keratinocyte proliferation and the role of mitogen‐activated protein kinases (MAPKs) in CGRP induced keratinocyte proliferation. Our data indicate CGRP increased [ 3 H]‐thymidine incorporation and MTT activity of HaCaT in a concentration‐dependent manner. CGRP also enhanced serum‐induced HaCaT cell proliferation. HaCaT cells cultured with CGRP had a significant increase in phosphorylated ERK1/2, p38 and JNK, and CGRP induced DNA synthesis was inhibited by PD 98059 or SB 203580, selective inhibitors of MAP kinase kinase (MEK, which is upstream from ERK) and p38, respectively. These findings suggest that HaCaT cell proliferate in response to CGRP, which is mediated by phosphorylation of ERK1/2 and p38 MAPK." @default.
• W2018477213 created "2016-06-24" @default.
• W2018477213 creator A5025206507 @default.
• W2018477213 creator A5027099198 @default.
• W2018477213 creator A5068885379 @default.
• W2018477213 creator A5069178263 @default.
• W2018477213 creator A5084402501 @default.
• W2018477213 date "2009-11-01" @default.
• W2018477213 modified "2023-10-15" @default.
• W2018477213 title "Calcitonin gene-related peptide increases proliferation of human HaCaT keratinocytes by activation of MAP kinases" @default.
• W2018477213 cites W1966393393 @default.
• W2018477213 cites W1967376453 @default.
• W2018477213 cites W1975275126 @default.
• W2018477213 cites W1987115540 @default.
• W2018477213 cites W1987498837 @default.
• W2018477213 cites W1988338105 @default.
• W2018477213 cites W1994809932 @default.
• W2018477213 cites W1997277570 @default.
• W2018477213 cites W2001413268 @default.
• W2018477213 cites W2007123442 @default.
• W2018477213 cites W2013316968 @default.
• W2018477213 cites W2020842224 @default.
• W2018477213 cites W2023954622 @default.
• W2018477213 cites W2036553065 @default.
• W2018477213 cites W2036792358 @default.
• W2018477213 cites W2052395782 @default.
• W2018477213 cites W2060630008 @default.
• W2018477213 cites W2064893229 @default.
• W2018477213 cites W2075554967 @default.
• W2018477213 cites W2094231516 @default.
• W2018477213 cites W2128730976 @default.
• W2018477213 cites W2133845446 @default.
• W2018477213 cites W2143464311 @default.
• W2018477213 cites W2150164895 @default.
• W2018477213 cites W2155124532 @default.
• W2018477213 cites W2161082279 @default.
• W2018477213 cites W2165310182 @default.
• W2018477213 doi "https://doi.org/10.1016/j.cellbi.2009.07.003" @default.
• W2018477213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19651223" @default.
• W2018477213 hasPublicationYear "2009" @default.
• W2018477213 type Work @default.
• W2018477213 sameAs 2018477213 @default.
• W2018477213 citedByCount "28" @default.
• W2018477213 countsByYear W20184772132012 @default.
• W2018477213 countsByYear W20184772132013 @default.
• W2018477213 countsByYear W20184772132014 @default.
• W2018477213 countsByYear W20184772132017 @default.
• W2018477213 countsByYear W20184772132020 @default.
• W2018477213 countsByYear W20184772132021 @default.
• W2018477213 countsByYear W20184772132022 @default.
• W2018477213 countsByYear W20184772132023 @default.
• W2018477213 crossrefType "journal-article" @default.
• W2018477213 hasAuthorship W2018477213A5025206507 @default.
• W2018477213 hasAuthorship W2018477213A5027099198 @default.
• W2018477213 hasAuthorship W2018477213A5068885379 @default.
• W2018477213 hasAuthorship W2018477213A5069178263 @default.
• W2018477213 hasAuthorship W2018477213A5084402501 @default.
• W2018477213 hasConcept C118303440 @default.
• W2018477213 hasConcept C118995209 @default.
• W2018477213 hasConcept C126322002 @default.
• W2018477213 hasConcept C132149769 @default.
• W2018477213 hasConcept C134018914 @default.
• W2018477213 hasConcept C153911025 @default.
• W2018477213 hasConcept C163170386 @default.
• W2018477213 hasConcept C170493617 @default.
• W2018477213 hasConcept C184235292 @default.
• W2018477213 hasConcept C185592680 @default.
• W2018477213 hasConcept C2777074287 @default.
• W2018477213 hasConcept C2779627488 @default.
• W2018477213 hasConcept C51551487 @default.
• W2018477213 hasConcept C54355233 @default.
• W2018477213 hasConcept C55493867 @default.
• W2018477213 hasConcept C57074206 @default.
• W2018477213 hasConcept C62112901 @default.
• W2018477213 hasConcept C71924100 @default.
• W2018477213 hasConcept C81885089 @default.
• W2018477213 hasConcept C86803240 @default.
• W2018477213 hasConcept C95444343 @default.
• W2018477213 hasConceptScore W2018477213C118303440 @default.
• W2018477213 hasConceptScore W2018477213C118995209 @default.
• W2018477213 hasConceptScore W2018477213C126322002 @default.
• W2018477213 hasConceptScore W2018477213C132149769 @default.
• W2018477213 hasConceptScore W2018477213C134018914 @default.
• W2018477213 hasConceptScore W2018477213C153911025 @default.
• W2018477213 hasConceptScore W2018477213C163170386 @default.
• W2018477213 hasConceptScore W2018477213C170493617 @default.
• W2018477213 hasConceptScore W2018477213C184235292 @default.
• W2018477213 hasConceptScore W2018477213C185592680 @default.
• W2018477213 hasConceptScore W2018477213C2777074287 @default.
• W2018477213 hasConceptScore W2018477213C2779627488 @default.
• W2018477213 hasConceptScore W2018477213C51551487 @default.
• W2018477213 hasConceptScore W2018477213C54355233 @default.
• W2018477213 hasConceptScore W2018477213C55493867 @default.
• W2018477213 hasConceptScore W2018477213C57074206 @default.
• W2018477213 hasConceptScore W2018477213C62112901 @default.
• W2018477213 hasConceptScore W2018477213C71924100 @default.
• W2018477213 hasConceptScore W2018477213C81885089 @default.
• W2018477213 hasConceptScore W2018477213C86803240 @default.

• next