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• W2018488830 abstract "Metabotropic glutamate receptor activation has been shown to be essential for establishment of long-term potentiation, a phenomenon increasingly thought to be associated with the laying down of permanent memory. However, these receptors may also play a part in the initiation of protein kinase C activity, which has been demonstrated to be involved in prelong-term memory processes. Blockade of the metabotropic glutamate receptors by the specific antagonist, (RS)-α-Methyl-4-carboxyphenylgycine (500 μM) is shown to induce amnesia during a long-term memory stage in day-old chicks trained on a passive avoidance task, and to have no effect on prelong-term stages. The results suggest a specific role for these receptors in a possibly LTP associated mechanism of memory processing." @default.
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• W2018488830 date "1995-01-01" @default.
• W2018488830 modified "2023-10-07" @default.
• W2018488830 title "Blockade of metabotropic glutamate receptors prevents long-term memory consolidation" @default.
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• W2018488830 doi "https://doi.org/10.1016/0361-9230(94)00222-m" @default.
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