FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018536444> ?p ?o ?g. }

• W2018536444 endingPage "522" @default.
• W2018536444 startingPage "515" @default.
• W2018536444 abstract "BACKGROUND. Dilatation of the ascending aorta (AA) is affected by extra-cellular matrix modifications and inflammation. A disintegrin and metalloproteases (ADAMs) may reveal differences between AA and ascending aortic dissection (AD). We characterized the inflammatory histology of AD and AA and examined the role of ADAM8 and -15 in these diseases. MATERIAL AND METHODS. Aortic wall histology and immunohistochemistry for leukocytes, T- and B-lymphocytes, plasma cells, macrophages, endothelial cells, smooth muscle cells, cell proliferation, elastase and Van-Gieson-staining were performed to 40 consecutive patients that underwent surgery for AA or AD. The expressions of ADAM8 and -15 mRNA and proteins were evaluated using QRT-PCR and immunohistochemistry. RESULTS. Thirty-four patients were enrolled, of which 29 had AA and five had AD of the ascending aorta. B-cells throughout the aortic wall and intimal plasma cells were more numerous during AD as compared with AA (p < 0.05). The gene expressions for ADAM8 and -15 were notably lower in AA as compared with AD. The median for down-regulation of ADAM8 and -15 in AA was -2.7 and -1.8, respectively. ADAM8 and -15 were mainly found in the media layer in patients with AD. Two of the patients with AA and increased ADAMs developed AD of the remaining aorta. CONCLUSIONS. The involvement of ADAM8 and -15 together with inflammation consisting of B-cells may indicate active remodelling of the aortic wall leading to AD." @default.
• W2018536444 created "2016-06-24" @default.
• W2018536444 creator A5020219839 @default.
• W2018536444 creator A5051078137 @default.
• W2018536444 creator A5052111584 @default.
• W2018536444 creator A5064884790 @default.
• W2018536444 creator A5070875834 @default.
• W2018536444 creator A5073029734 @default.
• W2018536444 creator A5080553980 @default.
• W2018536444 creator A5081986241 @default.
• W2018536444 creator A5083465668 @default.
• W2018536444 creator A5084986778 @default.
• W2018536444 date "2011-07-06" @default.
• W2018536444 modified "2023-10-18" @default.
• W2018536444 title "A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection" @default.
• W2018536444 cites W1543694559 @default.
• W2018536444 cites W1963754832 @default.
• W2018536444 cites W1971194086 @default.
• W2018536444 cites W1976065407 @default.
• W2018536444 cites W1976250864 @default.
• W2018536444 cites W1980191945 @default.
• W2018536444 cites W1980338551 @default.
• W2018536444 cites W1983995459 @default.
• W2018536444 cites W1985259009 @default.
• W2018536444 cites W2004055642 @default.
• W2018536444 cites W2016724941 @default.
• W2018536444 cites W2021989452 @default.
• W2018536444 cites W2026323415 @default.
• W2018536444 cites W2048356493 @default.
• W2018536444 cites W2053603627 @default.
• W2018536444 cites W2054216018 @default.
• W2018536444 cites W2057183833 @default.
• W2018536444 cites W2058778127 @default.
• W2018536444 cites W2059330089 @default.
• W2018536444 cites W2060937867 @default.
• W2018536444 cites W2061041332 @default.
• W2018536444 cites W2065646518 @default.
• W2018536444 cites W2078301727 @default.
• W2018536444 cites W2081929579 @default.
• W2018536444 cites W2107277218 @default.
• W2018536444 cites W2116474615 @default.
• W2018536444 cites W2119882682 @default.
• W2018536444 cites W2134112682 @default.
• W2018536444 cites W2144098617 @default.
• W2018536444 cites W2145544026 @default.
• W2018536444 cites W2150675666 @default.
• W2018536444 cites W2152205876 @default.
• W2018536444 cites W2153921909 @default.
• W2018536444 cites W2155248983 @default.
• W2018536444 cites W2158687967 @default.
• W2018536444 cites W2160578379 @default.
• W2018536444 cites W2160618519 @default.
• W2018536444 cites W2170735043 @default.
• W2018536444 cites W2416103545 @default.
• W2018536444 doi "https://doi.org/10.3109/00365513.2011.591939" @default.
• W2018536444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21728902" @default.
• W2018536444 hasPublicationYear "2011" @default.
• W2018536444 type Work @default.
• W2018536444 sameAs 2018536444 @default.
• W2018536444 citedByCount "17" @default.
• W2018536444 countsByYear W20185364442012 @default.
• W2018536444 countsByYear W20185364442013 @default.
• W2018536444 countsByYear W20185364442014 @default.
• W2018536444 countsByYear W20185364442015 @default.
• W2018536444 countsByYear W20185364442016 @default.
• W2018536444 countsByYear W20185364442017 @default.
• W2018536444 countsByYear W20185364442018 @default.
• W2018536444 countsByYear W20185364442020 @default.
• W2018536444 countsByYear W20185364442021 @default.
• W2018536444 countsByYear W20185364442022 @default.
• W2018536444 countsByYear W20185364442023 @default.
• W2018536444 crossrefType "journal-article" @default.
• W2018536444 hasAuthorship W2018536444A5020219839 @default.
• W2018536444 hasAuthorship W2018536444A5051078137 @default.
• W2018536444 hasAuthorship W2018536444A5052111584 @default.
• W2018536444 hasAuthorship W2018536444A5064884790 @default.
• W2018536444 hasAuthorship W2018536444A5070875834 @default.
• W2018536444 hasAuthorship W2018536444A5073029734 @default.
• W2018536444 hasAuthorship W2018536444A5080553980 @default.
• W2018536444 hasAuthorship W2018536444A5081986241 @default.
• W2018536444 hasAuthorship W2018536444A5083465668 @default.
• W2018536444 hasAuthorship W2018536444A5084986778 @default.
• W2018536444 hasConcept C109523444 @default.
• W2018536444 hasConcept C125473707 @default.
• W2018536444 hasConcept C126322002 @default.
• W2018536444 hasConcept C142724271 @default.
• W2018536444 hasConcept C204232928 @default.
• W2018536444 hasConcept C2778249958 @default.
• W2018536444 hasConcept C2778259572 @default.
• W2018536444 hasConcept C2779980429 @default.
• W2018536444 hasConcept C55728118 @default.
• W2018536444 hasConcept C64837602 @default.
• W2018536444 hasConcept C71924100 @default.
• W2018536444 hasConceptScore W2018536444C109523444 @default.
• W2018536444 hasConceptScore W2018536444C125473707 @default.
• W2018536444 hasConceptScore W2018536444C126322002 @default.
• W2018536444 hasConceptScore W2018536444C142724271 @default.
• W2018536444 hasConceptScore W2018536444C204232928 @default.

• next