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- W2018546041 abstract "Activity patterns and sleep-wake cycles are among the physiological processes that change most prominently as animals age, and are often good indicators of healthspan. In this study, we used the video-based high-resolution Behavioral Monitoring System (BMS) to monitor the daily activity cycle of tephritid fruit flies Anastrepha ludens over their lifetime. Surprisingly, there was no dramatic change in activity profile with respect to age if flies were consistently fed with a nutritionally balanced diet. However, if flies were fed with sugar-only diet, their activity profile decreased in amplitude at old age, suggesting that suboptimal diet affected activity patterns, and its detrimental effect may not manifest itself until the animal ages. Moreover, by simulating different modes of behavior monitoring with a range of resolution and comparing the resulting conclusions, we confirmed the superior performance of video-based monitoring using high-resolution BMS in accurately representing activity patterns in an insect model." @default.
- W2018546041 created "2016-06-24" @default.
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- W2018546041 date "2013-08-14" @default.
- W2018546041 modified "2023-09-26" @default.
- W2018546041 title "Correction: Corrigendum: Deleterious effect of suboptimal diet on rest-activity cycle in Anastrepha ludens manifests itself with age" @default.
- W2018546041 doi "https://doi.org/10.1038/srep02450" @default.
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