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- W2018563755 abstract "Polybrominated diphenyl ethers (PBDEs) are ubiquitous environmental contaminants due to their long half-life and widespread use as flame retardants in several consumer products, including plastics. In addition to other actions, these compounds are characterized as thyroid hormone disruptors. Thyroid hormones affect the function of nearly all tissues via their effects on cellular metabolism and the essential roles they play in differentiation and growth. Interference with thyroid hormone homeostasis by these environmental compounds, therefore, has the potential to impact development and every system in the body. Their presence in human breast milk is particularly troubling due to exposure of nursing children. The last trimester of pregnancy up to 2 years of age corresponds to a time of rapid neurodevelopment and represents a period of vulnerability to environmental insults. Rodent studies indicate that PBDEs may act as developmental neurotoxicants and effects on the reproductive system have been reported as well. Concerns exist regarding possible impacts of exposure, in particular ones which occur during development, on human health. This paper is part of a series of articles regarding contaminants in plastic and provides an overview regarding PBDEs, a class of flame-retardant additives to plastic. PBDEs possess a similar structure to the polychlorinated biphenyls (PCBs) previously used as lubricants in electrical generators and transformers until production was prohibited approximately 25 years ago. Parallels between the two compounds will be briefly made and in particular, as more epidemiological studies on PCBs are available than on PBDEs, a few examples concerning thyroid homeostasis, cognitive function and sexually dimorphic behavior in humans will be mentioned." @default.
- W2018563755 created "2016-06-24" @default.
- W2018563755 creator A5089743628 @default.
- W2018563755 date "2008-10-01" @default.
- W2018563755 modified "2023-10-14" @default.
- W2018563755 title "Overview of toxicological aspects of polybrominated diphenyl ethers: A flame-retardant additive in several consumer products" @default.
- W2018563755 cites W1655226046 @default.
- W2018563755 cites W1963688170 @default.
- W2018563755 cites W1970006572 @default.
- W2018563755 cites W1970357224 @default.
- W2018563755 cites W1970618773 @default.
- W2018563755 cites W1971425761 @default.
- W2018563755 cites W1974584868 @default.
- W2018563755 cites W1977337002 @default.
- W2018563755 cites W1979153690 @default.
- W2018563755 cites W1982071978 @default.
- W2018563755 cites W1984747222 @default.
- W2018563755 cites W1987227107 @default.
- W2018563755 cites W1988836111 @default.
- W2018563755 cites W1989634621 @default.
- W2018563755 cites W1995028694 @default.
- W2018563755 cites W1995239116 @default.
- W2018563755 cites W1996281342 @default.
- W2018563755 cites W1996718340 @default.
- W2018563755 cites W1997131093 @default.
- W2018563755 cites W1999853913 @default.
- W2018563755 cites W2003052366 @default.
- W2018563755 cites W2004637227 @default.
- W2018563755 cites W2005149088 @default.
- W2018563755 cites W2008235055 @default.
- W2018563755 cites W2008654117 @default.
- W2018563755 cites W2010773835 @default.
- W2018563755 cites W2014465432 @default.
- W2018563755 cites W2015707313 @default.
- W2018563755 cites W2017427536 @default.
- W2018563755 cites W2019007589 @default.
- W2018563755 cites W2019320153 @default.
- W2018563755 cites W2020213679 @default.
- W2018563755 cites W2024320576 @default.
- W2018563755 cites W2025175568 @default.
- W2018563755 cites W2028067582 @default.
- W2018563755 cites W2028156764 @default.
- W2018563755 cites W2028357583 @default.
- W2018563755 cites W2029092129 @default.
- W2018563755 cites W2029962071 @default.
- W2018563755 cites W2030625412 @default.
- W2018563755 cites W2032943366 @default.
- W2018563755 cites W2033423771 @default.
- W2018563755 cites W2034531454 @default.
- W2018563755 cites W2035389048 @default.
- W2018563755 cites W2035841034 @default.
- W2018563755 cites W2036976420 @default.
- W2018563755 cites W2037863743 @default.
- W2018563755 cites W2039105495 @default.
- W2018563755 cites W2041186805 @default.
- W2018563755 cites W2042896209 @default.
- W2018563755 cites W2043228024 @default.
- W2018563755 cites W2043482823 @default.
- W2018563755 cites W2046542973 @default.
- W2018563755 cites W2046752722 @default.
- W2018563755 cites W2049971492 @default.
- W2018563755 cites W2049978132 @default.
- W2018563755 cites W2051242813 @default.
- W2018563755 cites W2051934006 @default.
- W2018563755 cites W2052045922 @default.
- W2018563755 cites W2052394575 @default.
- W2018563755 cites W2053413857 @default.
- W2018563755 cites W2057881071 @default.
- W2018563755 cites W2059530652 @default.
- W2018563755 cites W2060990597 @default.
- W2018563755 cites W2061206887 @default.
- W2018563755 cites W2062257143 @default.
- W2018563755 cites W2064309637 @default.
- W2018563755 cites W2066646121 @default.
- W2018563755 cites W2070956362 @default.
- W2018563755 cites W2073717245 @default.
- W2018563755 cites W2074195698 @default.
- W2018563755 cites W2076158001 @default.
- W2018563755 cites W2076573331 @default.
- W2018563755 cites W2076994772 @default.
- W2018563755 cites W2079168199 @default.
- W2018563755 cites W2081225531 @default.
- W2018563755 cites W2083628030 @default.
- W2018563755 cites W2086420769 @default.
- W2018563755 cites W2087666593 @default.
- W2018563755 cites W2092337736 @default.
- W2018563755 cites W2094611776 @default.
- W2018563755 cites W2097063456 @default.
- W2018563755 cites W2100492886 @default.
- W2018563755 cites W2103282761 @default.
- W2018563755 cites W2104125840 @default.
- W2018563755 cites W2107608797 @default.
- W2018563755 cites W2109030521 @default.
- W2018563755 cites W2109561093 @default.
- W2018563755 cites W2109890295 @default.
- W2018563755 cites W2110611073 @default.
- W2018563755 cites W2111715758 @default.
- W2018563755 cites W2111909451 @default.