FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018569158> ?p ?o ?g. }

• W2018569158 endingPage "1443" @default.
• W2018569158 startingPage "1435" @default.
• W2018569158 abstract "Background. Previous studies in mice showed that respiratory syncytial virus (RSV) infection was associated with RSV RNA persistence. This study was designed to characterize the significance of RSV RNA persistence and its relation to RSV-induced chronic airway disease. Methods. Mice were inoculated with live RSV, UV light-treated RSV, heat-inactivated RSV, or medium. Bronchoalveolar lavage fluid samples were obtained and lung specimens were harvested on days 1, 5, and 42 after inoculation to assess lung inflammation, lung mRNA expression of interleukin (IL)-4, IL-5, IL-15, and interferon (IFN)-γ; RSV loads were assessed by culture and real-time polymerase chain reaction (PCR) and correlated with pulmonary function. Results. During the acute phase of infection, RSV loads as indicated by culture and PCR were significantly higher in mice inoculated with live RSV. On day 42, RSV RNA remained detectable only in mice inoculated with live or UV light-treated RSV. Lung inflammation, IFN-γ:IL-4 mRNA expression ratios, airway obstruction (AO), and airway hyperreactivity (AHR) were significantly increased in mice inoculated with live RSV. AO on day 5 and AHR on day 42 were significantly correlated with RSV RNA copy number in lung samples. Conclusions. Infection with live RSV induced acute and chronic airway disease that was associated with a predominantly Th-1 immune response and RSV RNA persistence that significantly correlated with pulmonary function abnormalities." @default.
• W2018569158 created "2016-06-24" @default.
• W2018569158 creator A5001794878 @default.
• W2018569158 creator A5002481881 @default.
• W2018569158 creator A5009464778 @default.
• W2018569158 creator A5024481748 @default.
• W2018569158 creator A5043310081 @default.
• W2018569158 creator A5049592946 @default.
• W2018569158 creator A5051740332 @default.
• W2018569158 creator A5053291711 @default.
• W2018569158 creator A5069122156 @default.
• W2018569158 creator A5075603631 @default.
• W2018569158 creator A5090552911 @default.
• W2018569158 creator A5090613517 @default.
• W2018569158 date "2008-11-15" @default.
• W2018569158 modified "2023-10-01" @default.
• W2018569158 title "Respiratory Syncytial Virus Persistence in the Lungs Correlates with Airway Hyperreactivity in the Mouse Model" @default.
• W2018569158 cites W1548012873 @default.
• W2018569158 cites W1790007141 @default.
• W2018569158 cites W1968766798 @default.
• W2018569158 cites W1975300426 @default.
• W2018569158 cites W1985593540 @default.
• W2018569158 cites W1991648511 @default.
• W2018569158 cites W1997745179 @default.
• W2018569158 cites W2005115634 @default.
• W2018569158 cites W2011042111 @default.
• W2018569158 cites W2019677652 @default.
• W2018569158 cites W2022259512 @default.
• W2018569158 cites W2027079842 @default.
• W2018569158 cites W2042387824 @default.
• W2018569158 cites W2049181225 @default.
• W2018569158 cites W2055312049 @default.
• W2018569158 cites W2056078604 @default.
• W2018569158 cites W2058607562 @default.
• W2018569158 cites W2062944553 @default.
• W2018569158 cites W2064791049 @default.
• W2018569158 cites W2071332592 @default.
• W2018569158 cites W2077831179 @default.
• W2018569158 cites W2078201105 @default.
• W2018569158 cites W2078706891 @default.
• W2018569158 cites W2087082234 @default.
• W2018569158 cites W2096445205 @default.
• W2018569158 cites W2097384942 @default.
• W2018569158 cites W2097772156 @default.
• W2018569158 cites W2106701493 @default.
• W2018569158 cites W2107277218 @default.
• W2018569158 cites W2112692443 @default.
• W2018569158 cites W2128507577 @default.
• W2018569158 cites W2129415799 @default.
• W2018569158 cites W2133624099 @default.
• W2018569158 cites W2140208397 @default.
• W2018569158 cites W2143485813 @default.
• W2018569158 cites W2145783587 @default.
• W2018569158 cites W2147216542 @default.
• W2018569158 cites W2147480427 @default.
• W2018569158 cites W2147516417 @default.
• W2018569158 cites W2152877910 @default.
• W2018569158 cites W2156857299 @default.
• W2018569158 cites W2166185793 @default.
• W2018569158 cites W2168919455 @default.
• W2018569158 cites W2192080449 @default.
• W2018569158 cites W2322654587 @default.
• W2018569158 cites W4235755408 @default.
• W2018569158 doi "https://doi.org/10.1086/592714" @default.
• W2018569158 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3689551" @default.
• W2018569158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18828742" @default.
• W2018569158 hasPublicationYear "2008" @default.
• W2018569158 type Work @default.
• W2018569158 sameAs 2018569158 @default.
• W2018569158 citedByCount "44" @default.
• W2018569158 countsByYear W20185691582012 @default.
• W2018569158 countsByYear W20185691582013 @default.
• W2018569158 countsByYear W20185691582014 @default.
• W2018569158 countsByYear W20185691582015 @default.
• W2018569158 countsByYear W20185691582016 @default.
• W2018569158 countsByYear W20185691582017 @default.
• W2018569158 countsByYear W20185691582018 @default.
• W2018569158 countsByYear W20185691582019 @default.
• W2018569158 countsByYear W20185691582021 @default.
• W2018569158 countsByYear W20185691582022 @default.
• W2018569158 countsByYear W20185691582023 @default.
• W2018569158 crossrefType "journal-article" @default.
• W2018569158 hasAuthorship W2018569158A5001794878 @default.
• W2018569158 hasAuthorship W2018569158A5002481881 @default.
• W2018569158 hasAuthorship W2018569158A5009464778 @default.
• W2018569158 hasAuthorship W2018569158A5024481748 @default.
• W2018569158 hasAuthorship W2018569158A5043310081 @default.
• W2018569158 hasAuthorship W2018569158A5049592946 @default.
• W2018569158 hasAuthorship W2018569158A5051740332 @default.
• W2018569158 hasAuthorship W2018569158A5053291711 @default.
• W2018569158 hasAuthorship W2018569158A5069122156 @default.
• W2018569158 hasAuthorship W2018569158A5075603631 @default.
• W2018569158 hasAuthorship W2018569158A5090552911 @default.
• W2018569158 hasAuthorship W2018569158A5090613517 @default.
• W2018569158 hasBestOaLocation W20185691582 @default.
• W2018569158 hasConcept C104317684 @default.
• W2018569158 hasConcept C126322002 @default.
• W2018569158 hasConcept C127413603 @default.

• next