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- W2018587181 abstract "<h3>Objective.</h3> —To determine if iodine tincture is a more effective skin antiseptic for blood culture collection than povidone-iodine, an iodophor. <h3>Design.</h3> —Pairwise comparisons across phases. In phases 1 and 3, blood culture skin preparation was performed with the iodophor; in phases 2 and 4, skin preparation was performed with iodine tincture. <h3>Setting.</h3> —Emergency department of a large urban teaching hospital. <h3>Patients.</h3> —All adult patients seen in the emergency department who had blood cultures collected because a systemic bacterial infection was suspected. <h3>Main Outcome Measure.</h3> —The blood culture contamination rate for the iodophor and iodine tincture skin preparations. <h3>Results.</h3> —A total of 8467 blood cultures were collected during the study, and 421 (4.97%) were classified as contaminated. The contamination rate for the blood cultures collected using the iodophor was 6.25%, and the contamination rate for the cultures using iodine tincture was 3.74%; this difference is statistically significant (<i>P</i><.00001). <h3>Conclusions.</h3> —The effectiveness of the skin antiseptic may be an important factor in determining contamination rate in blood culturing. If these results are confirmed by others, then institutions that have a high blood culture contamination rate when using an iodophor for skin preparation should consider changing to iodine tincture. (<i>JAMA</i>. 1993;269:1004-1006)" @default.
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- W2018587181 date "1993-02-24" @default.
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- W2018587181 title "Effect of lodophor vs Iodine Tincture Skin Preparation on Blood Culture Contamination Rate" @default.
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- W2018587181 doi "https://doi.org/10.1001/jama.1993.03500080052031" @default.
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