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- W2018604037 abstract "Rabbits, cats and rats with chronically implanted electrodes were employed in the study of the EEG and behavioral actions of eserine following reserpinization. In reserpinized animals eserine induces what may be referred to as a pharmacological model of the paradoxical sleep. EEG desynchronization, hippocampal theta waves, ocular movements and complete relaxation of the muscles, particularly of the neck, were conspicuous, especially in the rabbit and cats. Tertiary, but not quaternary, atropine completely antagonized these phenomena. The action of eserine at various times after reserpinization was explored; the effectiveness of eserine in inducing the phenomena in question seemed to run parallel with the kinetics of the depleting actions of reserpine. Small, repeated doses of reserpine were effective in inducing, in conjunction with eserine, the phenomena described. The importance of the cholinergic system for the PS is envisaged; its interplay with other systems is discussed." @default.
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- W2018604037 title "A pharmacological model of paradoxical sleep: The role of cholinergic and monoamine systems" @default.
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- W2018604037 doi "https://doi.org/10.1016/0031-9384(70)90061-2" @default.
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