FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018604879> ?p ?o ?g. }

• W2018604879 endingPage "4079" @default.
• W2018604879 startingPage "4075" @default.
• W2018604879 abstract "The major surface glycoprotein (G) of human respiratory syncytial (RS) virus has an estimated mature Mr of 84,000-90,000. Among a library of cDNA clones prepared from RS virus mRNAs, we identified clones that hybridized to a message that encoded a Mr 36,000 polypeptide that was specifically immunoprecipitated with anti-G antiserum. The amino acid sequence of the G protein backbone was determined by nucleotide sequence analysis of several of the cDNA clones. It contains a combination of structural features that make it unique among the known viral glycoproteins. The G mRNA is 918 nucleotides long and contains a single major open reading frame that encodes a polypeptide having 298 amino acid residues with a Mr of 32,587, a finding consistent with the Mr 36,000 estimate for the in vitro translation product of the G mRNA. This suggests that greater than 50% of the molecular weight of the mature glycoprotein may be contributed by carbohydrate. Glycosylation of G is largely resistant to tunicamycin, an inhibitor of the attachment of N-linked oligosaccharides, suggesting that the majority of the carbohydrate residues are attached via O-glycosidic bonds. In accordance with this, serine and threonine residues, the acceptor sites for O-linked oligosaccharides, comprise 30.6% of the total amino acid composition. There are also four potential acceptor sites for N-linked oligosaccharides. The amino acid sequence lacks both an NH2-terminal hydrophobic signal sequence and a COOH-terminal hydrophobic region. Instead, a strongly hydrophobic region is located between amino acid residues 38 and 66. This region may serve as both the signal to insert the nascent polypeptide through the membrane and as the membrane anchor site." @default.
• W2018604879 created "2016-06-24" @default.
• W2018604879 creator A5026357113 @default.
• W2018604879 creator A5027582911 @default.
• W2018604879 creator A5057682074 @default.
• W2018604879 creator A5062294703 @default.
• W2018604879 creator A5064173141 @default.
• W2018604879 creator A5079225835 @default.
• W2018604879 date "1985-06-01" @default.
• W2018604879 modified "2023-10-18" @default.
• W2018604879 title "Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein." @default.
• W2018604879 cites W14212766 @default.
• W2018604879 cites W1497259627 @default.
• W2018604879 cites W1544598568 @default.
• W2018604879 cites W1551098567 @default.
• W2018604879 cites W1558516755 @default.
• W2018604879 cites W1691660207 @default.
• W2018604879 cites W1812041296 @default.
• W2018604879 cites W1884088573 @default.
• W2018604879 cites W1983468246 @default.
• W2018604879 cites W1984352452 @default.
• W2018604879 cites W1998022671 @default.
• W2018604879 cites W2009105413 @default.
• W2018604879 cites W2027407556 @default.
• W2018604879 cites W2039816194 @default.
• W2018604879 cites W2039979335 @default.
• W2018604879 cites W2053418558 @default.
• W2018604879 cites W2057518954 @default.
• W2018604879 cites W2074987972 @default.
• W2018604879 cites W2084872132 @default.
• W2018604879 cites W2094478767 @default.
• W2018604879 cites W2124932154 @default.
• W2018604879 cites W2130119165 @default.
• W2018604879 cites W2146273181 @default.
• W2018604879 cites W2173897585 @default.
• W2018604879 cites W2328944885 @default.
• W2018604879 doi "https://doi.org/10.1073/pnas.82.12.4075" @default.
• W2018604879 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/397937" @default.
• W2018604879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3858865" @default.
• W2018604879 hasPublicationYear "1985" @default.
• W2018604879 type Work @default.
• W2018604879 sameAs 2018604879 @default.
• W2018604879 citedByCount "277" @default.
• W2018604879 countsByYear W20186048792012 @default.
• W2018604879 countsByYear W20186048792013 @default.
• W2018604879 countsByYear W20186048792014 @default.
• W2018604879 countsByYear W20186048792015 @default.
• W2018604879 countsByYear W20186048792016 @default.
• W2018604879 countsByYear W20186048792017 @default.
• W2018604879 countsByYear W20186048792018 @default.
• W2018604879 countsByYear W20186048792019 @default.
• W2018604879 countsByYear W20186048792020 @default.
• W2018604879 countsByYear W20186048792021 @default.
• W2018604879 countsByYear W20186048792022 @default.
• W2018604879 crossrefType "journal-article" @default.
• W2018604879 hasAuthorship W2018604879A5026357113 @default.
• W2018604879 hasAuthorship W2018604879A5027582911 @default.
• W2018604879 hasAuthorship W2018604879A5057682074 @default.
• W2018604879 hasAuthorship W2018604879A5062294703 @default.
• W2018604879 hasAuthorship W2018604879A5064173141 @default.
• W2018604879 hasAuthorship W2018604879A5079225835 @default.
• W2018604879 hasBestOaLocation W20186048792 @default.
• W2018604879 hasConcept C104317684 @default.
• W2018604879 hasConcept C10858879 @default.
• W2018604879 hasConcept C108625454 @default.
• W2018604879 hasConcept C11960822 @default.
• W2018604879 hasConcept C153911025 @default.
• W2018604879 hasConcept C167625842 @default.
• W2018604879 hasConcept C187882448 @default.
• W2018604879 hasConcept C2775880066 @default.
• W2018604879 hasConcept C2776414213 @default.
• W2018604879 hasConcept C2777313579 @default.
• W2018604879 hasConcept C515207424 @default.
• W2018604879 hasConcept C55493867 @default.
• W2018604879 hasConcept C84148353 @default.
• W2018604879 hasConcept C86803240 @default.
• W2018604879 hasConceptScore W2018604879C104317684 @default.
• W2018604879 hasConceptScore W2018604879C10858879 @default.
• W2018604879 hasConceptScore W2018604879C108625454 @default.
• W2018604879 hasConceptScore W2018604879C11960822 @default.
• W2018604879 hasConceptScore W2018604879C153911025 @default.
• W2018604879 hasConceptScore W2018604879C167625842 @default.
• W2018604879 hasConceptScore W2018604879C187882448 @default.
• W2018604879 hasConceptScore W2018604879C2775880066 @default.
• W2018604879 hasConceptScore W2018604879C2776414213 @default.
• W2018604879 hasConceptScore W2018604879C2777313579 @default.
• W2018604879 hasConceptScore W2018604879C515207424 @default.
• W2018604879 hasConceptScore W2018604879C55493867 @default.
• W2018604879 hasConceptScore W2018604879C84148353 @default.
• W2018604879 hasConceptScore W2018604879C86803240 @default.
• W2018604879 hasIssue "12" @default.
• W2018604879 hasLocation W20186048791 @default.
• W2018604879 hasLocation W20186048792 @default.
• W2018604879 hasLocation W20186048793 @default.
• W2018604879 hasLocation W20186048794 @default.
• W2018604879 hasOpenAccess W2018604879 @default.
• W2018604879 hasPrimaryLocation W20186048791 @default.
• W2018604879 hasRelatedWork W1481240978 @default.

• next