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- W2018608826 abstract "Signal amplification in conventional enzyme-based biosensors is not high enough to achieve the ultrasensitive detection of biomolecules. In recent years, signal amplification has been improved by combining enzymatic reactions with redox cycling or employing multienzyme labels per detection probe. Electrochemical–chemical redox cycling and electrochemical–chemical–chemical redox cycling allow ultrasensitive detection simply by including one or two more chemicals in a solution without the use of an additional enzyme and/or electrode. Multiple horseradish peroxidase labels on magnetic bead carriers provide high signal enhancement along with a multiplex detection possibility. In both cases, the detection procedures are the same as those in conventional enzyme-based electrochemical sensors." @default.
- W2018608826 created "2016-06-24" @default.
- W2018608826 creator A5090892663 @default.
- W2018608826 date "2012-08-01" @default.
- W2018608826 modified "2023-09-30" @default.
- W2018608826 title "Enzyme-based ultrasensitive electrochemical biosensors" @default.
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- W2018608826 doi "https://doi.org/10.1016/j.cbpa.2012.03.015" @default.
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