FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018620137> ?p ?o ?g. }

• W2018620137 endingPage "2195" @default.
• W2018620137 startingPage "2191" @default.
• W2018620137 abstract "Apoptosis was detected in Vero cell cultures expressing transfected dengue virus type 2 (DENV-2) genes. Approximately 17·5 and 51·5 % of cells expressing NS3 serine protease and NS2B-NS3185 serine protease precursor protein [NS2B-NS3185(pro)] genes, respectively, were apoptotic. The percentage of apoptotic cells was significantly higher in cell cultures expressing NS2B-NS3185(pro). NS2B-NS3185(pro) was detected as NS2B-NS3185(pro)-EGFP fusion protein in cytoplasmic vesicular structures in the apoptotic cells. Site-directed mutagenesis which replaced His51 with Ala within the protease catalytic triad significantly reduced the ability of the expressed NS3 and NS2B-NS3185(pro) to induce apoptosis. Results from the present study showed that DENV-2-encoded NS3 serine protease induces apoptosis, which is enhanced in cells expressing its precursor, NS2B-NS3185(pro). These findings suggest the importance of NS2B as a cofactor to NS3 protease-induced apoptosis." @default.
• W2018620137 created "2016-06-24" @default.
• W2018620137 creator A5007181259 @default.
• W2018620137 creator A5081218230 @default.
• W2018620137 date "2003-08-01" @default.
• W2018620137 modified "2023-10-14" @default.
• W2018620137 title "Dengue virus type 2 NS3 protease and NS2B-NS3 protease precursor induce apoptosis" @default.
• W2018620137 cites W1574175588 @default.
• W2018620137 cites W1618299283 @default.
• W2018620137 cites W1865324159 @default.
• W2018620137 cites W1957753312 @default.
• W2018620137 cites W2020942480 @default.
• W2018620137 cites W2021201659 @default.
• W2018620137 cites W2036093440 @default.
• W2018620137 cites W2037279384 @default.
• W2018620137 cites W2042409437 @default.
• W2018620137 cites W2060148547 @default.
• W2018620137 cites W2062725625 @default.
• W2018620137 cites W2079930944 @default.
• W2018620137 cites W2079949399 @default.
• W2018620137 cites W2101494056 @default.
• W2018620137 cites W2101573640 @default.
• W2018620137 cites W2102443458 @default.
• W2018620137 cites W2124279506 @default.
• W2018620137 cites W2124483903 @default.
• W2018620137 cites W2125525079 @default.
• W2018620137 cites W2147787249 @default.
• W2018620137 cites W2148230692 @default.
• W2018620137 cites W2149270925 @default.
• W2018620137 cites W2150029541 @default.
• W2018620137 cites W2153689486 @default.
• W2018620137 cites W2162653594 @default.
• W2018620137 cites W2164082417 @default.
• W2018620137 doi "https://doi.org/10.1099/vir.0.19022-0" @default.
• W2018620137 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12867651" @default.
• W2018620137 hasPublicationYear "2003" @default.
• W2018620137 type Work @default.
• W2018620137 sameAs 2018620137 @default.
• W2018620137 citedByCount "58" @default.
• W2018620137 countsByYear W20186201372012 @default.
• W2018620137 countsByYear W20186201372013 @default.
• W2018620137 countsByYear W20186201372014 @default.
• W2018620137 countsByYear W20186201372015 @default.
• W2018620137 countsByYear W20186201372016 @default.
• W2018620137 countsByYear W20186201372017 @default.
• W2018620137 countsByYear W20186201372018 @default.
• W2018620137 countsByYear W20186201372019 @default.
• W2018620137 countsByYear W20186201372020 @default.
• W2018620137 countsByYear W20186201372021 @default.
• W2018620137 countsByYear W20186201372022 @default.
• W2018620137 crossrefType "journal-article" @default.
• W2018620137 hasAuthorship W2018620137A5007181259 @default.
• W2018620137 hasAuthorship W2018620137A5081218230 @default.
• W2018620137 hasBestOaLocation W20186201371 @default.
• W2018620137 hasConcept C132379496 @default.
• W2018620137 hasConcept C140704245 @default.
• W2018620137 hasConcept C142462285 @default.
• W2018620137 hasConcept C153911025 @default.
• W2018620137 hasConcept C159047783 @default.
• W2018620137 hasConcept C181199279 @default.
• W2018620137 hasConcept C190283241 @default.
• W2018620137 hasConcept C2522874641 @default.
• W2018620137 hasConcept C2776408679 @default.
• W2018620137 hasConcept C2776714187 @default.
• W2018620137 hasConcept C2777807008 @default.
• W2018620137 hasConcept C2779635636 @default.
• W2018620137 hasConcept C2781143361 @default.
• W2018620137 hasConcept C2993143319 @default.
• W2018620137 hasConcept C55493867 @default.
• W2018620137 hasConcept C82553315 @default.
• W2018620137 hasConcept C83100098 @default.
• W2018620137 hasConcept C86803240 @default.
• W2018620137 hasConceptScore W2018620137C132379496 @default.
• W2018620137 hasConceptScore W2018620137C140704245 @default.
• W2018620137 hasConceptScore W2018620137C142462285 @default.
• W2018620137 hasConceptScore W2018620137C153911025 @default.
• W2018620137 hasConceptScore W2018620137C159047783 @default.
• W2018620137 hasConceptScore W2018620137C181199279 @default.
• W2018620137 hasConceptScore W2018620137C190283241 @default.
• W2018620137 hasConceptScore W2018620137C2522874641 @default.
• W2018620137 hasConceptScore W2018620137C2776408679 @default.
• W2018620137 hasConceptScore W2018620137C2776714187 @default.
• W2018620137 hasConceptScore W2018620137C2777807008 @default.
• W2018620137 hasConceptScore W2018620137C2779635636 @default.
• W2018620137 hasConceptScore W2018620137C2781143361 @default.
• W2018620137 hasConceptScore W2018620137C2993143319 @default.
• W2018620137 hasConceptScore W2018620137C55493867 @default.
• W2018620137 hasConceptScore W2018620137C82553315 @default.
• W2018620137 hasConceptScore W2018620137C83100098 @default.
• W2018620137 hasConceptScore W2018620137C86803240 @default.
• W2018620137 hasIssue "8" @default.
• W2018620137 hasLocation W20186201371 @default.
• W2018620137 hasLocation W20186201372 @default.
• W2018620137 hasOpenAccess W2018620137 @default.
• W2018620137 hasPrimaryLocation W20186201371 @default.
• W2018620137 hasRelatedWork W1979477181 @default.
• W2018620137 hasRelatedWork W2015939628 @default.
• W2018620137 hasRelatedWork W2032176260 @default.

• next