Matches in SemOpenAlex for { <https://semopenalex.org/work/W201862730> ?p ?o ?g. }
- W201862730 endingPage "34" @default.
- W201862730 startingPage "17" @default.
- W201862730 abstract "About 25 years ago the observation that neuropeptides serve as signalling molecules in the nervous system generated great expectations for drug industry. In this article the progress made since then in exploiting neuropeptide systems pharmacologically in psychiatry is highlighted. In affective disorders a number of neuropeptides seem to be causally involved in development and course of illness, especially corticotropin releasing hormone (CRH), vasopressin (AVP) and substance P, whose receptors are now targeted with small molecules designed to reduce depressive and anxiety symptoms. Although not exactly neuropeptides, also neurotrophins, may have a distinct role in antidepressant action and possibly also in causation of depression. Schizophrenia-like symptoms are caused by neurotensin (NT), supporting the notion that drugs interfering with NT systems are potential antipsychotics. Finally, sleep disorders, currently treated with hypnotics, that have serious adverse effects can be targeted with neuropeptides. According to the work by Axel Steiger several neuropeptides even if peripherally administered produce improvements of quality of sleep. All these observations call for intensified application of novel research tools necessary to exploit the potential of neuropeptide systems as psychopharmaceutical targets." @default.
- W201862730 created "2016-06-24" @default.
- W201862730 creator A5044329719 @default.
- W201862730 date "2003-01-01" @default.
- W201862730 modified "2023-10-17" @default.
- W201862730 title "The Role of Peptides in Treatment of Psychiatric Disorders" @default.
- W201862730 cites W1527225576 @default.
- W201862730 cites W1531005638 @default.
- W201862730 cites W1572525448 @default.
- W201862730 cites W1623788409 @default.
- W201862730 cites W1710423957 @default.
- W201862730 cites W1914011667 @default.
- W201862730 cites W1964125304 @default.
- W201862730 cites W1968271989 @default.
- W201862730 cites W1973994559 @default.
- W201862730 cites W1976727298 @default.
- W201862730 cites W1980055778 @default.
- W201862730 cites W1980498739 @default.
- W201862730 cites W1988230174 @default.
- W201862730 cites W1989142763 @default.
- W201862730 cites W1992731869 @default.
- W201862730 cites W1993003470 @default.
- W201862730 cites W1995005137 @default.
- W201862730 cites W1995277808 @default.
- W201862730 cites W1995556701 @default.
- W201862730 cites W1996405087 @default.
- W201862730 cites W2003547326 @default.
- W201862730 cites W2005254595 @default.
- W201862730 cites W2007135601 @default.
- W201862730 cites W2009548865 @default.
- W201862730 cites W2012850984 @default.
- W201862730 cites W2014207939 @default.
- W201862730 cites W2019316537 @default.
- W201862730 cites W2023800668 @default.
- W201862730 cites W2024839669 @default.
- W201862730 cites W2027593853 @default.
- W201862730 cites W2028521746 @default.
- W201862730 cites W2029277771 @default.
- W201862730 cites W2032395354 @default.
- W201862730 cites W2032947885 @default.
- W201862730 cites W2034456670 @default.
- W201862730 cites W2035860685 @default.
- W201862730 cites W2036604474 @default.
- W201862730 cites W2038073160 @default.
- W201862730 cites W2039567064 @default.
- W201862730 cites W2039702376 @default.
- W201862730 cites W2040727780 @default.
- W201862730 cites W2047295469 @default.
- W201862730 cites W2048178217 @default.
- W201862730 cites W2057792489 @default.
- W201862730 cites W2058523218 @default.
- W201862730 cites W2061730652 @default.
- W201862730 cites W2067609807 @default.
- W201862730 cites W2071070948 @default.
- W201862730 cites W2071783417 @default.
- W201862730 cites W2072023643 @default.
- W201862730 cites W2074698464 @default.
- W201862730 cites W2092655383 @default.
- W201862730 cites W2093484024 @default.
- W201862730 cites W2095836476 @default.
- W201862730 cites W2097408153 @default.
- W201862730 cites W2101758314 @default.
- W201862730 cites W2107195919 @default.
- W201862730 cites W2107337535 @default.
- W201862730 cites W2109452045 @default.
- W201862730 cites W2117560547 @default.
- W201862730 cites W2121878996 @default.
- W201862730 cites W2140178312 @default.
- W201862730 cites W2140471733 @default.
- W201862730 cites W2140799285 @default.
- W201862730 cites W2145981956 @default.
- W201862730 cites W2152390421 @default.
- W201862730 cites W2154989101 @default.
- W201862730 cites W2156994072 @default.
- W201862730 cites W2284345796 @default.
- W201862730 cites W2337178257 @default.
- W201862730 cites W2342828918 @default.
- W201862730 cites W241037007 @default.
- W201862730 doi "https://doi.org/10.1007/978-3-7091-6020-6_2" @default.
- W201862730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12830927" @default.
- W201862730 hasPublicationYear "2003" @default.
- W201862730 type Work @default.
- W201862730 sameAs 201862730 @default.
- W201862730 citedByCount "31" @default.
- W201862730 countsByYear W2018627302012 @default.
- W201862730 countsByYear W2018627302014 @default.
- W201862730 countsByYear W2018627302016 @default.
- W201862730 crossrefType "book-chapter" @default.
- W201862730 hasAuthorship W201862730A5044329719 @default.
- W201862730 hasConcept C118303440 @default.
- W201862730 hasConcept C118552586 @default.
- W201862730 hasConcept C126322002 @default.
- W201862730 hasConcept C15744967 @default.
- W201862730 hasConcept C169760540 @default.
- W201862730 hasConcept C170493617 @default.
- W201862730 hasConcept C2776412080 @default.
- W201862730 hasConcept C2778976297 @default.
- W201862730 hasConcept C2779177272 @default.