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- W2018654005 abstract "Isoprinosine and Imuthiol are non mitogenic immunomodulators active on T cell differentiation. In ARC patients, they modulate the circulating T cell receptor complex in terms of OKT4+ phenotype induction. This effect is not responsible for any expansion of the target population but for a partial inhibition of in vitro infection with LAV/HTLV III viral particles. At a clinical level, this means that these drugs may prove helpful in ARC patients when the virus has infected only a few helper cells." @default.
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- W2018654005 date "1986-01-01" @default.
- W2018654005 modified "2023-09-27" @default.
- W2018654005 title "Influence of immunomodulators on T lymphocyte differentiation in arc patients and resistance to LAV/HTLV III infection" @default.
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- W2018654005 doi "https://doi.org/10.1016/0147-9571(86)90020-2" @default.
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