FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018654772> ?p ?o ?g. }

• W2018654772 endingPage "614" @default.
• W2018654772 startingPage "605" @default.
• W2018654772 abstract "Biologic scaffolds composed of extracellular matrix (ECM) are utilized in numerous regenerative medicine applications to facilitate the constructive remodeling of tissues and organs. The mechanisms by which the host remodeling response occurs are not fully understood, but recent studies suggest that both constituent growth factors and biologically active degradation products derived from ECM play important roles. The objective of the present study was to determine if degradation of ECM scaffold materials in vitro by methods that are biochemically and physiologically relevant can yield products that possess chemotactic and/or mitogenic activities for fully differentiated mammalian endothelial cells and undifferentiated multipotential progenitor cells. ECM harvested from porcine urinary bladder was degraded enzymatically with pepsin/hydrochloric acid or papain. The ECM degradation products were tested for chemoattractant properties utilizing either 48-well chemotaxis filter migration microchambers or fluorescence-based filter migration assays, and were tested for mitogenic properties in cell proliferation assays. Results showed that ECM degradation products possessed chemotactic and mitogenic activities for multipotential progenitor cells and that the same degradation products inhibited both chemotaxis and proliferation of differentiated endothelial cells. These findings support the concept that degradation products of ECM bioscaffolds are important modulators of the recruitment and proliferation of appropriate cell types during the process of ECM scaffold remodeling." @default.
• W2018654772 created "2016-06-24" @default.
• W2018654772 creator A5017770880 @default.
• W2018654772 creator A5019847998 @default.
• W2018654772 creator A5027498069 @default.
• W2018654772 creator A5032202587 @default.
• W2018654772 creator A5040936050 @default.
• W2018654772 creator A5056570665 @default.
• W2018654772 creator A5066716873 @default.
• W2018654772 creator A5069636370 @default.
• W2018654772 creator A5073097748 @default.
• W2018654772 creator A5080254142 @default.
• W2018654772 creator A5036984968 @default.
• W2018654772 date "2009-03-01" @default.
• W2018654772 modified "2023-10-09" @default.
• W2018654772 title "Degradation Products of Extracellular Matrix Affect Cell Migration and Proliferation" @default.
• W2018654772 cites W1971950350 @default.
• W2018654772 cites W1986172289 @default.
• W2018654772 cites W1989238977 @default.
• W2018654772 cites W1991445463 @default.
• W2018654772 cites W1994495261 @default.
• W2018654772 cites W1995373597 @default.
• W2018654772 cites W2002246826 @default.
• W2018654772 cites W2006079390 @default.
• W2018654772 cites W2006139915 @default.
• W2018654772 cites W2017335231 @default.
• W2018654772 cites W2017429680 @default.
• W2018654772 cites W2024015130 @default.
• W2018654772 cites W2026778488 @default.
• W2018654772 cites W2031013234 @default.
• W2018654772 cites W2035790993 @default.
• W2018654772 cites W2037241293 @default.
• W2018654772 cites W2038747440 @default.
• W2018654772 cites W2047999162 @default.
• W2018654772 cites W2054556155 @default.
• W2018654772 cites W2055228395 @default.
• W2018654772 cites W2058014017 @default.
• W2018654772 cites W2061186377 @default.
• W2018654772 cites W2062051261 @default.
• W2018654772 cites W2064528501 @default.
• W2018654772 cites W2068465081 @default.
• W2018654772 cites W2077204544 @default.
• W2018654772 cites W2080825616 @default.
• W2018654772 cites W2081479208 @default.
• W2018654772 cites W2090502291 @default.
• W2018654772 cites W2091498007 @default.
• W2018654772 cites W2091782658 @default.
• W2018654772 cites W2093871975 @default.
• W2018654772 cites W2094322840 @default.
• W2018654772 cites W2101134052 @default.
• W2018654772 cites W2104753126 @default.
• W2018654772 cites W2111066407 @default.
• W2018654772 cites W2115363380 @default.
• W2018654772 cites W2127099066 @default.
• W2018654772 cites W2127383554 @default.
• W2018654772 cites W2129182120 @default.
• W2018654772 cites W2150538563 @default.
• W2018654772 cites W2150605894 @default.
• W2018654772 cites W2151838922 @default.
• W2018654772 cites W2168218089 @default.
• W2018654772 cites W2404483120 @default.
• W2018654772 cites W4241591217 @default.
• W2018654772 doi "https://doi.org/10.1089/ten.tea.2007.0425" @default.
• W2018654772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18652541" @default.
• W2018654772 hasPublicationYear "2009" @default.
• W2018654772 type Work @default.
• W2018654772 sameAs 2018654772 @default.
• W2018654772 citedByCount "339" @default.
• W2018654772 countsByYear W20186547722012 @default.
• W2018654772 countsByYear W20186547722013 @default.
• W2018654772 countsByYear W20186547722014 @default.
• W2018654772 countsByYear W20186547722015 @default.
• W2018654772 countsByYear W20186547722016 @default.
• W2018654772 countsByYear W20186547722017 @default.
• W2018654772 countsByYear W20186547722018 @default.
• W2018654772 countsByYear W20186547722019 @default.
• W2018654772 countsByYear W20186547722020 @default.
• W2018654772 countsByYear W20186547722021 @default.
• W2018654772 countsByYear W20186547722022 @default.
• W2018654772 countsByYear W20186547722023 @default.
• W2018654772 crossrefType "journal-article" @default.
• W2018654772 hasAuthorship W2018654772A5017770880 @default.
• W2018654772 hasAuthorship W2018654772A5019847998 @default.
• W2018654772 hasAuthorship W2018654772A5027498069 @default.
• W2018654772 hasAuthorship W2018654772A5032202587 @default.
• W2018654772 hasAuthorship W2018654772A5036984968 @default.
• W2018654772 hasAuthorship W2018654772A5040936050 @default.
• W2018654772 hasAuthorship W2018654772A5056570665 @default.
• W2018654772 hasAuthorship W2018654772A5066716873 @default.
• W2018654772 hasAuthorship W2018654772A5069636370 @default.
• W2018654772 hasAuthorship W2018654772A5073097748 @default.
• W2018654772 hasAuthorship W2018654772A5080254142 @default.
• W2018654772 hasConcept C10854531 @default.
• W2018654772 hasConcept C137738243 @default.
• W2018654772 hasConcept C1491633281 @default.
• W2018654772 hasConcept C170493617 @default.
• W2018654772 hasConcept C185592680 @default.
• W2018654772 hasConcept C189165786 @default.

• next